Cumulative Loss of Body Weight, Body Fat, and Lean Body Mass According to Study Group.

<p>(A) average cumulative weight loss (kg); (B) average cumulative fat loss (kg); (C) average cumulative loss of lean mass (kg) as a function of time. Values are means ± SEM. LC, low carbohydrate. LF, low fat.</p

Percent change in Initial Body Weight According to Intervention Arm by Month of Weight Loss.

<p>Detailed information on individual success in each intervention arm, box plots of the percent change from initial weight by intervention arm at each of the 6 times points were constructed in a format into which a symmetrical dot density plot was integrated. The box plots show each participant’s data as well as indicating the 25^th, 50^th and 75^th percentiles for weight change achieved. These plots show the progressive increments in change in body weight over time by intervention arm and permit a comprehensive view of the magnitude of variation in response.</p

Time-to-Event Analysis for Weight Loss Success According to Intervention Arm.

<p>Kaplan-Meier plots were constructed in order to quantify the time frame over which participants in each intervention arm achieved at least a 5%, or 10% reduction in body weight relative to initial body weight. Each plot shows the percent of women in each arm that achieved at least the stated percent weight loss by month. (A) greater than 90% of all women in both intervention arms achieved at least 5% weight loss with a median time to achieving this goal of 2 months (95% CI = 1 to 3 months). Change occurred more rapidly in the low carbohydrate intervention arm but the differences were not statistically significant, tested using a Cox proportional hazard model controlling for BMI, RMR, steps, and elapsed time from end of treatment. (B) median time to loss of ≥ 10% of initial body weight was 4 months (95% CI = 3 to 5 months). LC, low carbohydrate. LF, low fat.</p

Weight Loss Success by Intervention Arm.

<p>Values are n (% of total). The differences between intervention arms were not statistically significant.</p><p>Weight Loss Success by Intervention Arm.</p

Flow diagram for screening, assignment, and follow-up of the study participants.

<p>Flow diagram for screening, assignment, and follow-up of the study participants.</p