3,114 research outputs found

    Give the Boys a Trade : Gender and Job Choice in the 1890s

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    [Excerpt] It seems redundant (but is unfortunately not unnecessary) to say that this response emphasizes the gendered nature of the famed manliness of turn-of-the-century skilled workers. Davis Montgomery has described how the workers\u27 code celebrated individual self-assertion, but for the collective good, rather than for self-advancement. The process by which these skilled workers chose their jobs suggests an intermediate step: between the collective good of the union and the self-advancement\u27 of the individual stood the smaller collective unit of the male-headed household. The sense of what it meant to be a man thus not only holds the potential of explicating workers\u27 relationships with their employers and supervisors but also redounds back to their original choices of occupations, and in so doing prefigures family roles and relationships. These examples only begin to touch on the ways in which exploring male workers\u27 job decisions may open up new areas for research. Just as it has done for women\u27s labor history, raising these issues holds the potential of uncovering new insights into the connections between men\u27s workplace concerns and their family and community experiences. A labor history that fully takes gender into account in this way will be that much richer and, perhaps, that much more true to the realities of working-class life in the past

    1945-05-13, Greeting Card

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    https://digitalcommons.chapman.edu/fdevault_collection/1003/thumbnail.jp

    Satisfaction conjugale de la mère et relation au sein de la fratrie

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    Regulation Of Natural Killer T Cell Subset Development And Function By Slam Family Receptors

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    Semi-invariant natural killer T (iNKT) cells are critical components of the host immune response in peripheral tissues such as the lung, liver, and gut, and they play important roles in cancer, bacterial infections, autoimmunity, wound repair, and atherosclerosis. Tissue-resident iNKT cells exert their effects early in the developing immune response by rapidly producing a wide variety of cytokines and chemokines, and it was recently discovered that different tissues possess iNKT cell subsets that preferentially produce IFN-Îł (NKT1), IL-4 (NKT2), or IL-17 (NKT17). Despite their critical role in the immune response, the mechanisms that regulate iNKT cell function in the periphery remain unclear. Signaling lymphocyte activation marker (SLAM) proteins are cell surface-expressed molecular switches that are expressed on all hematopoietic cells. The nine SLAM family receptors serve a variety of functions including promotion of cell-cell adhesion, regulation of cytokine production, co-stimulation, and inhibition. Importantly, SLAM family receptors are critical for the development of iNKT cells. Yet, numerous efforts to ascribe discrete roles of SLAM family receptors in iNKT cell function has proven difficult. We conducted a comprehensive analysis of SLAM family receptor co-expression on iNKT cell subsets in the lung, spleen, liver, and thymus and identified co-expression profiles that varied in a tissue and strain-dependent manner. Interestingly, we found that SLAM family receptor expression profiles varied among different iNKT cell subsets. In particular, we noted a close association of SLAMf6 expression with the NKT2 and NKT17 subsets in both the periphery and in the thymus. Further investigation using SLAMf6-deficient mice revealed a critical role for SLAMf6 in NKT2 and NKT17 subset development, and in iNKT IL-4 and IL-17 cytokine production in the periphery. This investigation also revealed that the SLAMf6high NKT2 and NKT17 subsets exhibited significantly higher proliferative capacity than the NKT1 subset and the NKT2 and NKT17 proliferation was dependent, in part, on SLAMf6 expression. Since Slam family genes are highly polymorphic, we next investigated whether these polymorphisms regulated iNKT function. We employed a B6.129 congenic mouse exhibiting impaired NKT cell function, in which a 6.6 Mbp 129/SvJ locus encompassing Slam genes was introgressed onto the C57BL/6 background. To test the hypothesis that Slam gene polymorphisms regulate iNKT cell function, we refined this genetic interval by generating B6.129 subcongenic lines and assessing iNKT cell function. Unexpectedly, we found that while Slam gene polymorphisms in this model do regulate iNKT cell function, the dominant regulator was in a 0.14 Mbp interval centromeric to the Slam genes. Further experimentation revealed that impaired iNKT cell development and function was associated with changes in the expression of Fcgr3 (Fc gamma receptor III) on iNKT cells, suggesting it as a novel candidate gene regulating iNKT cell function. Taken together, these data reveal for the first time a specific role for SLAMf6 on NKT2 and NKT17 subset development and function. In addition, these data identify Fcgr3 as a novel candidate gene that regulates iNKT cell subset development and cytokine production. Cumulatively, these data reveal the presence of discrete regulatory mechanisms at work in different iNKT subsets, a finding that has broad implications for our understanding of iNKT-cell mediated immunity

    1945-05-02, Franz to Isa

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    https://digitalcommons.chapman.edu/fdevault_collection/1001/thumbnail.jp

    Beauty and the Beast Lighting Design

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    For Ohio Northern’s production of Beauty and the Beast, the director Matt Simpkins wanted to make a new aesthetic for the show: ominous, mysterious and dramatic yet still enchanting. This was not to be your typical Beauty and the Beast. Because of the director’s film background, the scenery was to act as film set where projections set the environment for each section. Lighting was to highlight the dark mood of the piece while also acting as the “close up” for the intimate nature many of the scenes have. Backlight was very important for separating the actors from the projections/scenery but also because of the desire to see the shafts of light coming thru the space. Between fog, dry ice and/or haze, one was always running during the show. Seeing actors in silhouette with the contrasts of light and dark was integral to the mood of the piece. Even during “Be Our Guest” the quintessential musical theatre extravaganza, Bella and Lumiere were the only two characters completely visible, the others were lit with sidelight, backlight or footlights

    1945-05-04, Franz to Family

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    https://digitalcommons.chapman.edu/fdevault_collection/1002/thumbnail.jp

    1944-10-27, Franz to Family

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    https://digitalcommons.chapman.edu/fdevault_collection/1000/thumbnail.jp

    The Raman Spectrum of Boron Trifluoride Gas

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    The Raman spectrum of BF3 was photographed using a purified preparation obtained from the thermal decomposition of C6H5N2BF4. Of the lines observed, that with the frequency 888 cm^—1 is certainly, and the band at 439–513 cm^—1 is probably due to BF3. The Raman frequencies and the infra-red results of Bailey et al. are assigned to the fundamental modes of vibrations
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