48 research outputs found
Low temperature and cost-effective growth of vertically aligned carbon nanofibers using spin-coated polymer-stabilized palladium nanocatalysts
We describe a fast and cost-effective process for the growth of carbon nanofibers (CNFs) at a temperature compatible with complementary metal oxide semiconductor technology, using highly stable polymer-Pd nanohybrid colloidal solutions of palladium catalyst nanoparticles (NPs). Two polymer-Pd nanohybrids, namely poly(lauryl methacrylate)-block-poly((2-acetoacetoxy) ethyl methacrylate)/Pd (LauMA(x)-b-AEMA(y)/Pd) and polyvinylpyrrolidone/Pd were prepared in organic solvents and spin-coated onto silicon substrates. Subsequently, vertically aligned CNFs were grown on these NPs by plasma enhanced chemical vapor deposition at different temperatures. The electrical properties of the grown CNFs were evaluated using an electrochemical method, commonly used for the characterization of supercapacitors. The results show that the polymer-Pd nanohybrid solutions offer the optimum size range of palladium catalyst NPs enabling the growth of CNFs at temperatures as low as 350 degrees C. Furthermore, the CNFs grown at such a low temperature are vertically aligned similar to the CNFs grown at 550 degrees C. Finally the capacitive behavior of these CNFs was similar to that of the CNFs grown at high temperature assuring the same electrical properties thus enabling their usage in different applications such as on-chip capacitors, interconnects, thermal heat sink and energy storage solutions
Early Neurodegeneration Progresses Independently of Microglial Activation by Heparan Sulfate in the Brain of Mucopolysaccharidosis IIIB Mice
BACKGROUND: In mucopolysaccharidosis type IIIB, a lysosomal storage disease causing early onset mental retardation in children, the production of abnormal oligosaccharidic fragments of heparan sulfate is associated with severe neuropathology and chronic brain inflammation. We addressed causative links between the biochemical, pathological and inflammatory disorders in a mouse model of this disease. METHODOLOGY/PRINCIPAL FINDINGS: In cell culture, heparan sulfate oligosaccharides activated microglial cells by signaling through the Toll-like receptor 4 and the adaptor protein MyD88. CD11b positive microglial cells and three-fold increased expression of mRNAs coding for the chemokine MIP1alpha were observed at 10 days in the brain cortex of MPSIIIB mice, but not in MPSIIIB mice deleted for the expression of Toll-like receptor 4 or the adaptor protein MyD88, indicating early priming of microglial cells by heparan sulfate oligosaccharides in the MPSIIIB mouse brain. Whereas the onset of brain inflammation was delayed for several months in doubly mutant versus MPSIIIB mice, the onset of disease markers expression was unchanged, indicating similar progression of the neurodegenerative process in the absence of microglial cell priming by heparan sulfate oligosaccharides. In contrast to younger mice, inflammation in aged MPSIIIB mice was not affected by TLR4/MyD88 deficiency. CONCLUSIONS/SIGNIFICANCE: These results indicate priming of microglia by HS oligosaccharides through the TLR4/MyD88 pathway. Although intrinsic to the disease, this phenomenon is not a major determinant of the neurodegenerative process. Inflammation may still contribute to neurodegeneration in late stages of the disease, albeit independent of TLR4/MyD88. The results support the view that neurodegeneration is primarily cell autonomous in this pediatric disease
Low-temperature growth of nitrogen-doped carbon nanofibers by acetonitrile catalytic CVD using Ni-based catalysts
ALMA Band 5 receiver cartridge. Design, performance, and commissioning
We describe the design, performance, and commissioning results for the new ALMA Band 5 receiver channel, 163–211 GHz, which is in the final stage of full deployment and expected to be available for observations in 2018. This manuscript provides the description of the new ALMA Band 5 receiver cartridge and serves as a reference for observers using the ALMA Band 5 receiver for observations. At the time of writing this paper, the ALMA Band 5 Production Consortium consisting of NOVA Instrumentation group, based in Groningen, NL, and GARD in Sweden have produced and delivered to ALMA Observatory over 60 receiver cartridges. All 60 cartridges fulfil the new more stringent specifications for Band 5 and demonstrate excellent noise temperatures, typically below 45 K single sideband (SSB) at 4 K detector physical temperature and below 35 K SSB at 3.5 K (typical for operation at the ALMA Frontend), providing the average sideband rejection better than 15 dB, and the integrated cross-polarization level better than –25 dB. The 70 warm cartridge assemblies, hosting Band 5 local oscillator and DC bias electronics, have been produced and delivered to ALMA by NRAO. The commissioning results confirm the excellent performance of the receivers
FABRICATION AND CHARACTERIZATION OF SUBMICRON FABRICATION AND CHARACTERIZATION OF SUBMICRON AlGaN/GaN HEMTS
ABSTRACT Using our in-house 0.3 µm mushroom gate process, AlGaN/GaN high electron mobility transistors (HEMTs) with total gate periphery up to 0.6 mm were fabricated and characterized. The transistors were processed on an AlGaN/GaN heterostructure grown by MBE on sapphire. Output current densities up to 1 A/mm and extrinsic DC-transconductances (g m ) of 240 mS/mm were measured. Extrinsic cut-off frequencies (f t ) of 35 GHz, maximum frequencies of oscillation (f max ) of 75 GHz, were calculated from S-parameters measurements. On wafer Load-Pull measurements were performed without any active cooling on HEMTs of different sizes. Continuous wave (CW) output power densities up to 3.2 W/mm at 6 dB compression and 1.9 W/mm at 3 dB compression at 6 GHz were achieved
Spectral domain simulation of SIS frequency multiplication
In this paper, we compare simulations to experimental results for a new SIS frequency multiplier. To simulate these devices, we developed software based on spectral-domain analysis, which is ideal for simulating higherorder harmonics such as those present in a multiplier. In addition, we included the embedding circuit and interpolated the experimental I-V curve to allow the simulation to capture the experimental system as closely as possible. For the experimental data, results were taken from a new SIS frequency multiplier that has recently been developed at the Chalmers University of Technology. Previously, these experimental results were compared to simulations based on Tucker theory. Here, we compare these results to spectraldomain simulations. Qualitatively, the inclusion of embedding impedances and the use of spectral-domain analysis improves the agreement between simulation and experiment. The software can now be used to design multipliers with high output power and high conversion efficiency