910 research outputs found

    Dual-PEEC Modeling of a Two-Port TEM Cell for VHF Applications

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    Two-port TEM cells with rectangular cross section are commonly used to produce plane electromagnetic waves with high electric field. The non-uniform structure makes the use of numerical methods extremely useful in the design phase in order to achieve a very good behavior of the TEM cell over a wide frequency range of operation. In this paper an extended version of PEEC is used to study a real device and results are compared with experimental ones

    Wittgenstein on Aesthetics / Aesthetics on Wittgenstein

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    Low temperature upcycling of vitreous byproduct of the MSW plasma processing into multifunctional porous glass-ceramics

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    Mixtures of glass residues, deriving from the plasma processing of municipal solid waste (\u2018Plasmastone\u2019), and recycled glasses have been already converted into highly porous glass-ceramics by application of an inorganic gel casting technique (foaming, by intensive mechanical stirring, of alkali activated slurries) followed by sintering at 1000\ub0C. The full potential of recycled glass, however, has not been disclosed yet. The present investigation, in fact, demonstrates that boro-alumino-silicate glass, from discarded pharmaceutical vials, may allow for sintering of cellular glass-ceramics at particularly low temperature, i.e. at 800\ub0C. The full stabilisation of heavy metals from Plasmastone (already assessed for treatments at 1000\ub0C) is not compromised, whereas the low processing temperatures favour the separation of magnetite, in turn imparting new functionalities (e.g. electromagnetic shielding) to waste-derived glass-ceramic foams

    An energy saving solution applied to the final use of electrical and lighting systems of school buildings managed by Perugia Province

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    In this paper, a study and design of energy conservation actions and the obtention of Energy Efficiency Titles, according to the Italian Ministerial Decree 20th July 2004, applied to lighting and electrical systems in a school district managed by Perugia Province (Italy), is presented. Specifically, the analysis regarded the replacement of neon lamps with high efficiency ones, and the power factor correction of the electrical system with a lower value. The work was carried out through an energy audit of some school buildings. From the results of this energy audit, project solutions were developed and a technical and economical feasibility study was made. This study was then extended to the whole school building fleet managed by Perugia Province. The results of this work were validated by a commercial feasibility assessment through an ESCo

    Natural compounds as therapeutic agents: The case of human topoisomerase ib

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    Natural products are widely used as source for drugs development. An interesting example is represented by natural drugs developed against human topoisomerase IB, a ubiquitous enzyme involved in many cellular processes where several topological problems occur due the formation of supercoiled DNA. Human topoisomerase IB, involved in the solution of such problems relaxing the DNA cleaving and religating a single DNA strand, represents an important target in anticancer therapy. Several natural compounds inhibiting or poisoning this enzyme are under investigation as possible new drugs. This review summarizes the natural products that target human topoisomerase IB that may be used as the lead compounds to develop new anticancer drugs. Moreover, the natural compounds and their derivatives that are in clinical trial are also commented on

    Feasibility study and design of a low-energy residential unit in Sagarmatha park for environmental impact reduction of high altitude buildings

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    The project presented in this paper is geographically set within Sagarmatha National Park, a wide area located on the Nepalese mountainside of Everest and declared as World Heritage Site since 1979. In recent years the park was the focus of several studies and initiatives, aimed at improving the management of its many-sided ecosystem, significantly influenced by climate change and increase of human activities and tourism, which occurred from the end of the 1970s, as well as by practices that are harmful both to human health and to our environment (e.g. burn up kerosene or animal excrements in order to obtain heat). Research work has focused on designing a residential unit that meets population needs, in terms of simplicity of realization, replicability, use of local materials, environmental compatibility and exploitation of available renewable energies. For this purpose a thorough analysis was conducted to identify the housing standard characteristic of reference context and Sherpa people, concerning indoor thermal comfort conditions, construction techniques, availability and skills of local workforce. Data necessary for the design phase were obtained through a collaboration with researchers of Ev-K2-CNR center, active at 5,050 meters a.s.l. in Nepal at the base of Mount Everest with a laboratory/observatory (known as the "Pyramid") for highaltitude meteorological studies since 1989. Climate conditions were registered by specific monitoring stations at certain times (2002-2008); during preliminary stage, these values were considered representative of the local context chosen for the project, that is Namche Bazar, a village located within the park, in a central point both from the logistic and altimetric/weather points of view. For the residential unit under investigation, two different constructive approaches were selected and compared: earthbags and straw bales. Both techniques have several advantages, in particular availability of raw material (jute bags, soil, straw), simplicity (e.g. earthbag constructions are realized using the ancient technique of pisé, combined with flexible bags or tubes), durability, insulation performance, costeffectiveness. Through a specific software for calculation of winter/summer thermal loads, different combinations of selections of structure and insulation were examined for both solutions, in order to achieve the optimum for the case study. Furthermore on the base of data monitored on site, a specific assessment was carried out to evaluate the potential of solar and wind resources. Aiming at entirely covering the heat and electric energy needs by exploiting renewable energy sources, various plant configurations were finally assumed. Every single choice was made to reduce human influence on land resources, such as timber, and to improve internal and external environmental quality

    Techno-economic assessment of an industrial carbon capture hub sharing a cement rotary kiln as sorbent regenerator

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    The concept of CCS cluster brings together multiple CO2 industrial emitters using shared capture and/or transportation infrastructure and offers several advantages for network partners compared with point-to-point individual projects. It reduces costs for CCS, and enables CO2 capture from small volume industrial facilities. The proposed concept connects a cluster of industrial sites with significant heat demands with a cement plant through the implementation of a Ca-looping CCS system. This system treats the flue gas from all the industrial emitters in independent boiler/carbonators while uses the kiln furnace as calciner for the cement and the capture plant. The carbonator reactors located in each one of the industry sites are fed by CaO from the cement plant to capture the CO2 content of their own flue gas. After carbonation reaction, the exhaust sorbent is transported back to the cement plant for regeneration in the kiln furnace. The aim of this work is to analyse the techno-economic feasibility of the proposed Ca-looping CCS cluster. The economic assessment, assuming 20 euro/ton CaO and carbon market 30 euro/ton CO2 points out the feasibility of this kind of centralized carbon capture system to handle the carbon from small emitters. Results show that the operating costs of small companies that use coal or natural gas reduce from 21.3 Meuro to 18.8 Meuro or from 25.5 to 23.0 Meuro. For the cement industry this income lessens its operating costs 1.9 Meuro lower than a reference situation where CCS is only implemented in cement plant

    Zinc ion coordination as a modulating factor of the ZnuA histidine-rich loop flexibility: a molecular modeling and fluorescence spectroscopy study

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    ZnuA is the soluble component of the high-affinity ZnuABC zinc transporter belonging to the ATP-binding cassette-type periplasmic Zn-binding proteins. The zinc transporter ZnuABC is composed by three proteins: ZnuB, the membrane permease, ZnuC, the ATPase component and ZnuA, the soluble periplasmic metal-binding protein which captures Zn and delivers it to ZnuB. The ZnuA protein contains a charged flexible loop, rich in histidines and acidic residues, showing significant species-specific differences. Various studies have established that this loop contributes to the formation of a secondary zinc binding site, which has been proposed to be important in the acquisition of periplasmic Zn for its delivery to ZnuB or for regulation of zinc uptake. Due to its high mobility the structure of the histidine-rich loop has never been solved by X-ray diffraction studies. In this paper, through a combined use of molecular modeling, mutagenesis and fluorescence spectroscopy, we confirm the presence of two zinc binding sites characterized by different affinities for the metal ion and show that the flexibility of the loop is modulated by the binding of the zinc ions to the protein. The data obtained by fluorescence spectroscopy have then be used to validate a 3D model including the unsolved histidine-rich loop
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