The role of response selection and input monitoring in solving simple arithmetical products

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Membrane recycling after endocytosis of cationized ferritin in cultured rat hepatocytes

SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Studies on the liver galactose and fucose recognition systems in cultured and isolated adult rat hepatocytes

SCOPUS: NotDefined.jFLWNOinfo:eu-repo/semantics/publishe

Galactose-specific adsorptive endocytosis: An ultrastructural qualitative and quantitative study in cultured rat hepatocytes

Using galactosylated bovine serum albumin coupled to colloidal gold (galBSA-CG) as a probe, the receptor-mediated endocytosis pathway has been analyzed qualitatively and quantitatively at the ultrastructural level in cultured rat hepatocytes. The results showed that galBSA-CG was specifically recognized by the asialoglycoprotein receptor of the hepatocytes, thus confirming biochemical findings. The probe was preferentially bound in coated pits of the cell surface. When bound elsewhere on the plasma membrane, it apparently moved towards coated regions. In both cases, it was then internalized via coated vesicles. The galBSA-CG passed through pleiomorphic tubular structures and in endosomes, a pool of smooth-surfaced vesicles of various size (50-350 nm), before transiently accumulating in multivesicular bodies. The latter then fused with lysosomes where the glycoproteinic moiety of the probe was degraded, as judged by the flocculated aspect of the accumulated gold particles. About 10% of the internalized ligand was recycled back to the cell surface via secreting vesicles containing lipoprotein-like particles without having apparently passed through lysosomes, which suggests the existence of a pre-lysosomal sorting mechanism of the endocytosed material. Functional recovery of the morphologically restored biliary polarity of hepatocytes in culture was indicated by the fact that galBSA-CG finally appeared in the reconstituted bile canaliculi.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Ultrastructural and biochemical properties of isolated hepatocytes and hyperplastic nodules from diethylnitrosamine-treated livers

SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

Input monitoring and response selection as components of executive control in pro-saccades and anti-saccades

Several studies have shown that anti-saccades, more than pro-saccades, are executed under executive control. It is argued that executive control subsumes a variety of controlled processes. The present study tested whether some of these underlying processes are involved in the execution of anti-saccades. An experiment is reported in which two such processes were parametrically varied, namely input monitoring and response selection. This resulted in four selective interference conditions obtained by factorially combining the degree of input monitoring and the presence of response selection in the interference task. The four tasks were combined with a primary task which required the participants to perform either pro-saccades or anti-saccades. By comparison of performance in these dual-task conditions and performance in single-task conditions, it was shown that anti-saccades, but not pro-saccades, were delayed when the secondary task required input monitoring or response selection. The results are discussed with respect to theoretical attempts to deconstruct the concept of executive control