Exploring the Impact of Mindfulness on Adolescents: A Mixed Methods Approach

As social emotional learning gains greater focus, identifying effective interventions for high-risk students, such as students with Emotional/ Behavioral Disorder (EBD), becomes a priority. Mindfulness, as an intervention, offers a unique set of skills to increase emotional awareness and regulation, while also teaching key social emotional skills (Singh et al, 2007). Mindfulness, or the nonjudgmental observation of one\u27s thoughts, feelings, and emotions, has roots in Buddhist philosophy, but is used secularly in the fields of psychology, medicine, and education (Baer, 2003). In this mixed methods study, the researcher aims to examine the experiences of adolescents who have EBD at an alternative high school as they participate in a mindfulness curriculum taught in their PE/Health class. Data was collected before, during, and after the teaching of the mindfulness intervention, vis-à-vis interviews, journal entries, mindfulness measures, and behavioral trackers. The researcher shows the applicability of mindfulness to the students\u27 lives

A Multiyear Investigation of Combating Bullying in Middle School: Stakeholder Perspectives

Working collaboratively to address bullying among middle school students is an ongoing challenge. This study used participatory action research to collaborate with key stakeholders within a middle school to identify needs and implement more effective practices. Extensive qualitative and quantitative data are presented, along with process recommendations for bringing different stakeholders together for a sustained change effort

Role of Drug Repurposing in Cancer Treatment and Liposomal Approach of Drug Targeting

Cancer is the leading cause of death, and incidences are increasing significantly and patients suffering from it desperately need a complete cure from it. The science of using an already-invented drug that has been approved by the FDA for a new application is known as “drug repurposing.” Currently, scientists are drawn to drug repositioning science in order to investigate existing drugs for newer therapeutic uses and cancer treatment. Because of their unique ability to target cancer cells, recently repurposed drugs and the liposomal approach are effective in the treatment of cancer. Liposomes are nanovesicles that are drastically flexible, rapidly penetrate deeper layers of cells, and enhance intracellular uptake. More importantly, liposomes are biocompatible, biodegradable; entrap both hydrophobic and hydrophilic drugs. This chapter summarizes various approaches to drug repurposing, as well as drug repurposing methods, advantages and limitations of drug repurposing, and a liposomal approach to using repurposed drugs in cancer targeting. This chapter also summarizes liposomal structure, drug loading, and the mechanism of liposomes in targeted cancer treatment. The lipid-based liposomal approach is emerging as a powerful technique for improving drug solubility, bioavailability, reducing side effects, and improving the therapeutic efficacy of repurposed drugs for cancer treatment

Atypical Ischemic Optic Neuropathy in a Patient With Ophthalmic Artery Calcification

The clinical presentation of ischemic optic neuropathy (ION) often follows a certain pattern which allows it to be categorized as arteritic or non-arteritic, and anterior or posterior ION. Here we report a unique case of ION associated with ophthalmic artery (OA) calcification, which does not follow any typical pattern of ION subtypes

Sugar β-ketoesers: new chirons in the synthesis of 6-deoxyheptulosurono-7,4-lactones

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