1 research outputs found
Nickel Phosphite/Phosphine-Catalyzed C–S Cross-Coupling of Aryl Chlorides and Thiols
A method for the coupling of aryl
chlorides and thiophenols using
an air-stable nickel(0) catalyst is described. This thioetherification
procedure can be effectively applied to a range of electronically
diverse aryl/heteroaryl chlorides without more expensive metal catalysts
such as palladium, iridium, or ruthenium. This investigation also
illustrates both, a variety of thiol coupling partners and, in certain
cases, the use of Cs<sub>2</sub>CO<sub>3</sub>