19 research outputs found
VUELTA CICLISTA A ESPAÑA [Material gráfico]
Copia digital. Madrid : Ministerio de Educación, Cultura y Deporte, 201
Variation of IC<sub>50</sub> against Dd2 with exposure time.
<p>IC<sub>50</sub> after 24 hours in blue; IC50 after 48 hours in red. The IC50 values presented were obtained from two distinct experiments run in duplicate each.</p
2D structures of the isolated compounds.
<p>DES1-Quercitrin, DES2-Afzelin, DES3-Quercetin, DES4-methyl 3,4,5-trihydroxybenzoate ; DES5-Sitosterol 3-O-β-D-glucopyranoside sterol .</p
Additional file 1: of Heterogeneity in the in vitro susceptibility of Loa loa microfilariae to drugs commonly used in parasitological infections
Table S1. Effects of different drug concentrations on the motility of L. loa mf. (DOCX 33 kb
A principal component analysis (PCA) plot, showing the comparison of the chemical space defined by the NPs in AfroDb (green) and the chemical space represented by NPs in the ChemBridge Diversity (red) databases.
<p>A principal component analysis (PCA) plot, showing the comparison of the chemical space defined by the NPs in AfroDb (green) and the chemical space represented by NPs in the ChemBridge Diversity (red) databases.</p
Distribution curves for #stars within the AfroDb library, along with the standard “drug-like”, “lead-like” and “fragment-like” subsets.
<p>Blue = AfroDb library, red = “drug-like” subset, green = “lead-like” subset and violet = “fragment-like” subset.</p
Bar chart showing the distribution of the compounds within AfroDb by region of collection.
<p>Bar chart showing the distribution of the compounds within AfroDb by region of collection.</p
Distibution curves for some computed ADME parameters.
<p>(A) logB/B, (B) log<i>K</i><sub>HSA</sub>, (C) logHERG. For subfigure B, the <i>x</i>-axis label is the lower limit of binned data, e.g. −2 is equivalent to −2 to −1. The colour codes are according to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0078085#pone-0078085-g005" target="_blank">Figure 5</a>.</p
MCSS panel in AfroDb, featuring the most common cyclic structures included in the database.
<p>MCSS panel in AfroDb, featuring the most common cyclic structures included in the database.</p
2D structures of selected promising compounds derived from the African flora and included in AfroDb.
<p>2D structures of selected promising compounds derived from the African flora and included in AfroDb.</p