Antibody responses to <i>Ae</i>. <i>aegypti</i> and <i>Ae</i>. <i>polynesiensis</i> SGE from cohorts from different contexts of exposure.

<p>The figure presents the individual IgG responses (ΔOD) against <i>Ae</i>. <i>aegypti</i> (A) and <i>Ae</i>. <i>polynesiensis</i> (B) SGE of residents from Martinique (n = 46), New-Caledonia (n = 19), Bolivia (n = 30) and Reunion (n = 33). The horizontal bars indicate the median value in each group and the dotted lines correspond to the positivity thresholds calculated from the cohort of metropolitan French residents. The percentage of responders in each cohort is shown above the plot. Residents from Martinique, New Caledonia and Bolivia, are typically exposed to <i>Ae</i>. <i>aegypti</i> bites. In Reunion island, <i>Ae</i>. <i>albopictus</i> is the main <i>Aedes</i> species while <i>Ae</i>. <i>aegypti</i> is cryptic. <i>Ae</i>. <i>polynesiensis</i> is not present in these islands or countries.</p

Antibody responses to <i>Ae</i>. <i>aegypti</i> and <i>Ae</i>. <i>polynesiensis</i> SGE in French Polynesian residents.

<p>The figure presents the individual IgG responses (ΔOD) against <i>Ae</i>. <i>aegypti</i> (A) and <i>Ae</i>. <i>polynesiensis</i> (B) SGE in metropolitan France (n = 66) and in Tahiti and Moorea islands (French Polynesia, n = 47) residents. Each triangle or dot represents an individual sample and the horizontal bar indicates the median value. The dotted lines correspond to the positivity thresholds calculated from the cohort of metropolitan French residents, not exposed to these <i>Aedes</i> species (0.16 for <i>Ae</i>. <i>aegypti</i> and 0.13 for <i>Ae</i>. <i>polynesiensis</i>). The percentage of responders (positive samples) in the Tahiti-Moorea cohort is shown above the plot. The non-parametric Mann-Whitney test was used to compare groups.</p

Evolution of antibody responses to <i>Ae</i>. <i>aegypti</i> and <i>Ae</i>. <i>polynesiensis</i> SGE in military personnel.

<p>The figure presents individual IgG responses (ΔOD) to <i>Ae</i>. <i>aegypti</i> (A) and <i>Ae</i>. <i>polynesiensis</i> (B) SGE of French military personnel (n = 13) assigned in Tahiti island (French Polynesia). Blood from the same individual was sampled two weeks after arrival and one year later (paired data). Each triangle or dot represents an individual serum and the horizontal bar indicates the median value. The dotted lines correspond to the positivity thresholds calculated from the cohort of metropolitan French residents (0.16 and 0.13 for <i>Ae</i>. <i>aegypti</i> and <i>Ae</i>. <i>polynesiensis</i>, respectively). Percentages of responders are shown above each plot. The non-parametric Wilcoxon test was used to compare the paired groups.</p

Amino-acid sequence of gSG6 Peptides.

<p>Amino-acid sequence of the SG6 protein of <i>Anopheles gambiae</i> (gi:13537666) is presented and sequences of the selected peptides, gSG6-P1 to gSG6-P5, are underlined. Signal peptide (SP) sequence is indicating by dotted underline.</p