1 research outputs found
Influence of aluminum salts on COVID-19 infected patients
Background/aim: Based on the antiviral and antibacterial properties of
aluminum salts, we aimed to find out the influence of aluminum salts on
COVID-19 infected patients.
Materials and methods: We performed an observational retrospective
cohort study which includes the patients diagnosed as COVID-19 and
received aluminum salts in addition to actual treatments during
hospitalization as the treatment group (Alum Group). Patients who
received standard COVID-19 treatment protocols in the Infectious
Diseases Clinics were included as the Control Group. Clinical findings,
laboratory parameters, length of stay, survival, radiological follow-up,
intensive care and mechanical ventilation needs, the presence of
comorbidity, polymerase chain reaction (PCR) tests, symptoms, symptom
recovery times, hospital stay times, treatment protocols, and clinical
presence of pneumonia were examined in all patients. Advanced chemical
composition analyzes of existing aluminum salts were also performed.
Results: A total of 109 patients, 54 in the alum group and 55 in the
control group, were included in the study. None of the patients in the
aluminum group developed side effects due to the intake of aluminum
salt. Survival status was significantly different between the two groups
as there were 5 loss in the Control Group and none in the Alum Group (P
= 0.023). The symptom recovery time was significantly shorter in the
Alum Group; 2 (1-3) vs. 1 (1-2) days, P= 0.003. According to the paired
samples analyses of the comparison between hospitalization and
discharge, CRP levels significantly drops in the Alum Group (from 54.09
to 27, P = 0.001) but not in the Control Group. The drop was
significantly same for the lactate dehydrogenase (LDH) and procalcitonin
levels with P = 0.001.
Conclusion: It has been observed that aluminum salts have beneficial
effects in COVID-19 infected cases. Considering the low systemic
toxicity of intermittent oral intake of aluminum salts as food
supplements and the fact that pandemic control is still not achieved,
the use of aluminum salts is promising