606 research outputs found

    Modulation of Circumstellar Extinction in a Young Binary System with a Low-Mass Companion in a Noncoplanar Orbit

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    The cyclic activity model of a young star with the low-mass secondary component (q = M2/M1 <= 0.1) accreting a matter from circumbinary disk is considered. It is assumed that the orbit is circular and the disk and orbital planes are non-coplanar. Sets of hydrodynamics models of such a system have been calculated by the SPH method and then the variations of the circumstellar extinction and phase light curves were determined. The calculations showed that depending on the model parameters and orientation of the system in regards to an observer the different in shape and amplitude light curves can be observed. An important property of the considered models is also the dependence of the mass accretion rate onto the components on the phase of the orbital period. The results of the calculation can be used for analysis of the cyclic activity of UX Ori stars and young stars with the long-lasting eclipses.Comment: 14 pages, 7 figure

    Assessment of pharmacological activity and bioavailability of the new derivative 1,3,4-thiadiazole

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    Acexazolamide is a new derivative of 1,3,4-thiadiazole and acexamic acid. In animal experiments, acute toxicity, pharmacological activity and bioavailability of acexazolamide were evaluate

    Some Aspects of Political Leadership on the Example of Historical Persona

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    The article is dedicated to analysis of influence of Hong Xiuquan’s on the course of Taiping Rebellion. The main focus of the work is directed on the issue of how the given historical persona has been shaped as a leader of low-income layers of Chinese population. In order to illuminate this question, the author observes the central socio-political ideas implemented by Hong Xiuquan during the Taiping Rebellion as well as his religious views, which had a fundamental role in Taiping’s movement ideology. In the course of the article, the author scrutinizes historical data which indicates such qualities of Hong Xiuquan as striving to achieve the highest outcomes, his persistence in realization of set tasks and ability to lead millions of Chinese peasants purposing on the radical reformation in Chinese state, which had experienced a deep crisis. On the other hand, the article demonstrates Hong Xiuquan’s qualities which have negatively affected the course of the revolutionary movement. To be precise, in the article are presented disadvantages of applying principles of mystical worldview and self-deification to the process of administration. In conclusion, the author, relying on the historical sources, highlights the significance of Hong Xiuquan’s personality and peculiarities of his leadership style in the context of their imprint on the Chinese revolutionary processes in the middle of the XIX century

    BANKRUPTCY LAW AS AN INSTRUMENT OF REDISTRIBUTION OF CORPORATE CONTROL: A RETROSPECTIVE ANALYSIS

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    The authors trace the stages of improvement of the Russian legislation on bankruptcy from the perspective of the redistribution and even interception of corporate control in the course of arbitration proceedings. The presented analysis shows the retrospective logic of formation of legal mechanisms and current areas of concern, the understanding of which can prevent irreversible situation on change of corporate control in the company

    Effect of cell-photosensitizer binding and cell density on microbial photoinactivation, Antimicrob

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    Photodynamic therapy involves the use of nontoxic dyes called photosensitizers and visible light to produce reactive oxygen species and cell killing. It is being studied as an alternative method of killing pathogens in localized infections due to the increasing problem of multiantibiotic resistance. Although much has been learned about the mechanisms of microbial killing, there is still uncertainty about whether dyes must bind to and penetrate various classes of microbe in order to produce effective killing after illumination. In this report, we compare the interactions of three antimicrobial photosensitizers: rose bengal (RB), toluidine blue O (TBO), and a poly-L-lysine chlorin(e6) conjugate (pL-ce6) with representative members of three classes of pathogens; Escherichia coli (gram-negative bacteria), Staphylococcus aureus (gram-positive bacteria), Candida albicans (yeast). We compared fluence-dependent cell survival after illumination with the appropriate wavelengths of light before and after extracellular dye had been washed out and used three 10-fold dilutions of cell concentration. pL-ce6 was overall the most powerful photosensitizer, was equally effective with and without washing, and showed a strong dependence on cell concentration. TBO was less effective in all cases after washing, and the dependence on cell concentration was less pronounced. RB was ineffective after washing (except for S. aureus) but still showed a dependence on cell concentration. The overall order of susceptibility was S. aureus &gt; E. coli &gt; C. albicans, but C. albicans cells were 10 to 50 times bigger than the bacteria. We conclude that the number and mass of the cells compete both for available dye binding and for extracellularly generated reactive oxygen species
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