79 research outputs found
Pioneers in biomedical optics: special section honoring professor Frans F. Jobsis of Duke University.
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Pioneers in Biomedical Optics: Special Section Honoring Professor Frans F. Jöbsis of Duke University
Assessment of an in situ temporal calibration method for time-resolved optical tomography
A 32-channel time-resolved optical imaging device is de- veloped at University College London to produce functional images of the neonatal brain and the female breast. Reconstruction of images using time-resolved measurements of transmitted light requires careful calibration of the temporal characteristics of the measurement system. Since they can often vary over a period of time, it is desirable to evaluate these characteristics immediately after, or prior to, the acqui- sition of image data. A calibration technique is investigated that is based on the measurement of light back-reflected from the surface of the object being imaged. This is facilitated by coupling each detector channel with an individual source fiber. A Monte Carlo model is em- ployed to investigate the influence of the optical properties of the object on the back-reflected signal. The results of simulations indicate that their influence may be small enough to be ignored in some cases, or could be largely accounted for by a small adjustment to the cali- brated data. The effectiveness of the method is briefly demonstrated by imaging a solid object with tissue-equivalent optical properties
Spatiotemporal variations of zooplankton community in a shallow tropical brackish lagoon (Sontecomapan, Veracruz, Mexico)
A validation method for near-infrared spectroscopy based tissue oximeters for cerebral and somatic tissue oxygen saturation measurements
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