Sex differences in the associations between L-arginine pathway metabolites, skeletal muscle mass and function, and their responses to resistance exercise, in old age

This work was supported by the Biotechnology and Biological Sciences Research Council (BB/J015911/1) and was registered at clinicaltrials.gov (ClinicalTrials. gov Identifier: NCT02843009). Supplementary email included with articlePeer reviewedPostprin

Towards a definition of sarcopenia--results from epidemiologic studies

The age-related loss of muscle mass, also called sarcopenia, is receiving increasing attention in aging research. While the concept is frequently being used in research settings and introduced to clinical settings, thus far no consensus on its definition has been established. This article provides an overview of the history of sarcopenia definitions proposed in the literature thus far. It will describe the methodology used to develop the cutpoints for low muscle mass (or strength) in large epidemiological studies, how sarcopenia based on these cutpoints relates to functional outcomes, and the advantages and disadvantages of the different definitions. This overview will contribute to the current need to develop a consensus definition of sarcopenia which can be used in all relevant settings. The Journal of Nutrition, Health & Aging©

Police posing as juveniles online to catch sex offenders: Is it working?

Abstract This paper explores the extent and effectiveness of proactive investigations in which investigators pose as minors on the Internet to catch potential sex offenders. It utilizes a subsample of cases from the National Juvenile Online Victimization Survey, which concerned persons arrested for Internet sex crimes against minors in the year beginning July 1, 2000. Results suggest proactive investigations represented a significant proportion (25%) of all arrests for Internet sex crimes against minors. Such investigations were being conducted at all levels of law enforcement. The online personas assumed by investigators paralleled the ages and genders of real youth victimized in sex crimes that started as online encounters. These proactive investigations accessed an offender group that appeared somewhat less deviant in terms of adult sexual behavior and arrest history but equally deviant as other online offenders in terms of possession of child pornography. Prosecution of these cases produced high rates of guilty pleas and low rates of dismissed or dropped cases. The entrapment, fantasy or role-playing, and factual impossibility defenses were used but not successfully. Findings suggest that the Internet sometimes allows law enforcement to interdict before a youth is victimized, gather solid evidence of offenses, and find and track some offenders