Level of motion sickness based on heart rate variability when reading inside a fully automated vehicle

This study investigates the level of experienced motion sickness when performing reading while being driven in fully automated driving under three different conditions. One condition was without any intervention while the other two conditions were with the visual (VPIS) and haptic (HPIS) peripheral information system. Both systems provided the upcoming navigational information in the lateral direction three seconds before the turning/cornering was done. It was hypothesized that with the peripheral information systems, the experienced motion sickness would be reduced compared to the condition where a peripheral information system was not present. Eighteen participants with severe motion sickness susceptibility were carefully chosen to undergo the conditions using an instrumented vehicle with the Wizard-of-Oz approach. The participants were required to read from a tablet during the whole 15-minutes of automated driving. Results from the heart rate variability (beats per minute, root means square of successive differences, and high-frequency component) indicated no statistically significant changes (p &lt; 0.05) in motion sickness found with the presence of HPIS and VPIS when performing reading when being driven in automated mode. However, results from this study were mixed and inconclusive, but overall findings indicated mild motion sickness was found in both VPIS and HPIS conditions.</p

Gaining Situation Awareness Through A Vibrotactile Display To Mitigate Motion Sickness In Fully-Automated Driving Cars

Many previous studies mention that passive drivers or passengers of fullyautomated driving cars have less awareness of the surrounding and more experience to motion sickness symptoms when engaging in non-driving tasks. This occurrence is especially magnified when riding in an urban area with lots of junctions and corners. The aim of the current study is to investigate the effects of peripheral information about upcoming manoeuvres through a vibrotactile display in increasing the fully-automated driving car passengers’ awareness of situations and mitigating their motion sickness level. Twenty participants took part in the experiment which used a Wizard of Oz method to simulate autonomous driving, and the experiment was conducted in an instrumented car on a real road environment. Objective and subjective measurements were gathered. The results show that the implementation of the vibrotactile display increased situation awareness but failed to reduce the motion sickness. This study concludes that in order to mitigate motion sickness inside a fully-automated driving car, more specific information need to be included in the peripheral information. In addition, a device that can actively help in controlling the posture movements should also be implemented in the vehicle

Development of a Clinical Simulation Protocol for the Transfer of a Premature Fetal Manikin to the Perinatal-Life-Support System

Introduction:At present, Perinatal-Life-Support (PLS) research is progressing to offer extreme premature infants an extracorporeal environment for extended growth that mimics the natural womb closely. During the early phase development of this novel life-support technology, validation and training could be facilitated by the use of a medical simulation. By doing so, the need for animal testing can be greatly reduced. Within this abstract, the development to realize a wellorchestrated clinical simulation protocol is described, tailored to the specific needs of novel procedure(s) regarding the transfer of a premature fetus from the maternal uterus to the PLS system.Materials &amp; Methods:Throughout protocol development an iterative approach is used, initiated with a literature analysis and a review of existing obstetrics guidelines for premature births. Next, co-creation sessions and interviews with medical and engineering experts led to a holistic understanding of fetal physiology, patient and specialist needs, current procedures, task divisions, hospital resources and drug specifications. Expert feedback on drafts, checklists and an explanatory step-by-step video, led to multiple re-designs as unforeseen procedural difficulties arose. Verified with available data from literature, multiple perspectives and options were analyzed and weighed to ensure the advancement of a safe, hygienic, effective, and user-friendly simulation protocol.Results:We describe the development process of a simulation protocol and showcase an overview of the current protocol design through an infographic, outlining the different phases and tasks during a transfer procedure and the planning of involved medical experts within the operating theatre. We demonstrate that an iterative approach to protocol development for an unprecedented procedure allows for a comprehensive understanding of the challenges that a transfer to the PLS-system could bring.Conclusions:Using medical simulation during the early phase development process of the PLS-system allows us to train and validate novel practices, in particular the transfer procedure. With the demonstrated approach we aim to establish a thorough simulation protocol by providing a step-by-step plan, informed by literature and expert consultation. We expect to offer a realistic simulation training whilst also informing requirements for the future development of PLS-related devices and their validation

Transfer Of A Preterm Baby From A Natural Womb

The present invention relates to a transfer assembly for transferring a preterm baby from a natural womb of a pregnant mammal to a transfer bag. The present invention further relates to a kit-of-parts for assembling a transfer assembly. Also the present invention relates to a transfer device and/or a birth canal retractor for use in a transfer assembly of the present invention. An alternative transfer device is provided as well. Further, the present invention relates to a method for transferring a preterm baby from a natural womb of a pregnant mammal to a transfer bag

Simulation-based development: shaping clinical procedures for extra-uterine life support technology

Background Research into Artificial Placenta and Artifcial Womb (APAW) technology for extremely premature infants (born &lt; 28 weeks of gestation) is currently being conducted in animal studies and shows promising results. Because of the unprecedented nature of a potential treatment and the high-risk and low incidence of occurrence, translation to the human condition is a complex task. Consequently, the obstetric procedure, the act of transferring the infant from the pregnant woman to the APAW system, has not yet been established for human patients. The use of simulation-based user-centered development allows for a safe environment in which protocols and devices can be conceptualized and tested. Our aim is to use participatory design principles in a simulation context, to gain and inte‑ grate the user perspectives in the early design phase of a protocol for this novel procedure.Methods Simulation protocols and prototypes were developed using an iterative participatory design approach; usability testing, including general and task specifc feedback, was obtained from participants with clinical expertise from a range of disciplines. The procedure made use of fetal and maternal manikins and included animations and protocol task cards.Results Physical simulation with the active participation of clinicians led to the difusion of tacit knowledge and an iteratively formed shared understanding of the requirements and values that needed to be implemented in the procedure. At each sequel, participant input was translated into simulation protocols and design adjustments.Conclusion This work demonstrates that simulation-based participatory design can aid in shaping the future of clinical procedure and product development and rehearsing future implementation with healthcare professional

Simulation-based development: shaping clinical procedures for extra-uterine life support technology

Background Research into Artificial Placenta and Artifcial Womb (APAW) technology for extremely premature infants (born &lt; 28 weeks of gestation) is currently being conducted in animal studies and shows promising results. Because of the unprecedented nature of a potential treatment and the high-risk and low incidence of occurrence, translation to the human condition is a complex task. Consequently, the obstetric procedure, the act of transferring the infant from the pregnant woman to the APAW system, has not yet been established for human patients. The use of simulation-based user-centered development allows for a safe environment in which protocols and devices can be conceptualized and tested. Our aim is to use participatory design principles in a simulation context, to gain and inte‑ grate the user perspectives in the early design phase of a protocol for this novel procedure.Methods Simulation protocols and prototypes were developed using an iterative participatory design approach; usability testing, including general and task specifc feedback, was obtained from participants with clinical expertise from a range of disciplines. The procedure made use of fetal and maternal manikins and included animations and protocol task cards.Results Physical simulation with the active participation of clinicians led to the difusion of tacit knowledge and an iteratively formed shared understanding of the requirements and values that needed to be implemented in the procedure. At each sequel, participant input was translated into simulation protocols and design adjustments.Conclusion This work demonstrates that simulation-based participatory design can aid in shaping the future of clinical procedure and product development and rehearsing future implementation with healthcare professional

An efficient automatic tool path generator for 2 1/2D free-form pockets

This paper describes an efficient tool path generator, capable of automatically generating the NC code needed to manufacture arbitrarily shaped pockets with constant depth. The pockets are defined by contours consisting of line-segments and arcs, and may contain islands of unremoved material (also defined by contours of line-segments and arcs). The algorithm used to construct the contour parallel tool path is based on Voronoi diagrams and has an O(n log(n)) complexity, where n denotes the number of contour-segments defining the pocket's boundary

Exploration of Contributory Factors to an Unpleasant Bracing Experience of Adolescent Idiopathic Scoliosis Patients: a Quantitative and Qualitative Research

Background: To obtain a better understanding of the wearing habits and preferences of Adolescent Idiopathic Scoliosis (AIS) patients undergoing rigid brace treatment, we examine what factors contribute to patients’ perceived discomfort during the treatment. Methods: Seventeen AIS patients treated with a rigid brace were recruited. We asked them to complete a questionnaire and participate in an interview study. Finally, we measure the interface corrective force and perceived discomfort with the participants for different positions and assess the correlation. Results: Our survey reveals that participants scored the lowest in the domains of environmental factors, psycho-spiritual factors, satisfaction, and self-image. Appearance anxiety, physical and psychological discomfort and inconvenience were the three most frequently mentioned problems in the interviews on participants’ daily bracing experiences. A significant, moderately positive relationship between corrective force and discomfort level was found only when participants were lying on their left side, but not in any of the other positions. No significant correlation between treatment length and perceived discomfort was found. Conclusions: Future work should focus on reducing the psychological burden and the inconvenience of wearing a brace, rather than on reducing physical discomfort resulting from the corrective force

Towards A Premature Fetal Manikin For Model-driven Simulation To Validate Perinatal Life Support Technologies

Background and Aims Perinatal-Life-Support (PLS) research is progressing to provide extreme premature infants a safe extracorporeal environment for further growth. A crucial step before being accepted into healthcare is the careful validation of life-support technology. However, clinical trials with living subjects yields great ethical concerns and limits testing and training of early-stage concepts. A promising alternative can be found in manikins, which can resemble infants on an anatomical and even physiological level. Methods An analysis was performed defining the design framework for the manikin to function as a validation model for PLS-technologies. A scientific literature review was conducted to identify parameters involved in the physiologic events that need to be prevented when transferring a perinate into a PLS-system, avoiding neonatal transition and maintaining fetal status. Results In our proposed framework, output of embedded sensors is compared to parameter threshold values as set in a linked computational model. The manikin’s embedded actuators could display symptoms, serving as a feedback loop during testing and training. The parameters include temperature, lung aeration, liquid clearance of lungs, umbilical cord compression, heart rate, blood pressure and flow. Symptoms include chest expansion, gasp reflex, cyanosis, vasospasm, and decreased fetal movement. Lastly, based on MRI scans, a 3D manikin prototype was developed that contains space for hardware integration. Conclusions The development of a simulation to validate a life-support system, not yet tested on humans, is unprecedented. With the proposed framework and requirements, we expect improved feedback during dimensional testing and training, allowing for design improvements and eventually promote success of future clinical trials