Evaluation of occupational exposure to different levels of mixed organic solvents and cognitive function in the painting unit of an automotive industry

Background: The cognitive function could be affected following exposure to organic solvents.The purpose of this study was to examine the cognitive performance of workers exposed to different levels of organic solvents in a painting unit of an automotive industry.Methods: This case-control study was conducted, in 2017, on 121 and 111 workers from the painting and assembly units of an automotive industry as the case and control groups,respectively. Exposure of workers to organic solvents were determined according to National Institute for Occupational Safety and Health (NIOSH) method. The cognitive performance of the studied population was evaluated by the computerized tests.Results: The obtained scores of the N-Back in 1 and 2 blocks and the simple reaction time tests(SRTTs) were significantly differed in the exposed group (p 0.05). Moreover, a significant relationship between the hazard quotient and the cognitive function test scores were observed except the Stroop test.Conclusion: Exposure to organic solvents affect the cognitive functions even below the Occupational Exposure Limits (OELs). Moreover, workers with high exposure levels of organic solvents had highest risk of poor memory and reaction time

The Relationship Between Perception of Disease and Quality of Life in Patients with Acne Vulgaris from 2013 to 2014

Background: Acne vulgaris is a common skin disease that can affect people in any ages. The development of acne have adverse effects on life quality. Psychological disorders increased in these patients and their psycho social activities have been affected. Since few studies have been done regarding illness perception in people with acne in Iran, this study aimed to investigate the association of perception of acne disease and quality of life in central of IranMethods: we analyzed 200 patients Acne Vulgaris referred to Khatam-Al Anbia in 2013-14 by questionnaire of perception of disease (Brief IPQ) and quality of life (DLQL. the data was analyzed using t-test and Chi-square by SPSS-16Results: Mean age of patients was 24.3 years and 158 people (79%) were women and 42 people (21 %) were men. Mean quality life score in women was 8.79±5.3 and in men was 8.69±5.18. Most patients had moderate acne and duration of their disease was between 1 to 5 years. 136 people were 18 to 25 years old and 64 persons were higher than 25 years. The mean perception scores in men and women were 51.83 and 53.26 respectively In this study, there was a relation between sex (P=0.03), Acne severity and duration with quality of life score.Conclusion: Women and patients with severe acne and longer duration of symptoms had higher quality life score that had more disorder in life.. There was relation between perception and sex and duration of symptoms

The Effects of Whole Word Reading Program on Expressive Vocabulary of Persian-Speaking Children with Down Syndrome

Objectives: Reading is a language skill based on visual modality which recently is addressed as a facilitator of expressive language in children with Down syndrome. The aim was designing a whole word reading protocol and examining its effects on the language skills of children with Down syndrome. Methods: A whole word reading protocol was developed and was examined through a single-subject study with time-series design. The protocol was made up of 50 pictures of nouns which were used through assessment and treatment. The vocabulary stimuli were selected from the receptive lexicon of each child. Three children with Down syndrome (trisomy 21) participated in the study (3 Females, mean age=6.1 years, mean IQ=44), and each participant received an individualized treatment up to 20 sessions. Visual graphs and C-statistic test were used for data analysis. Results: As a result of the treatment, naming ability of treated words was increased statistically in all children (Z=2.46>1.64 Z=1.75>1.6 and Z=2.37>1.64). Discussion: Whole word reading protocol seems to be effective in improving expressive vocabulary in children with Down syndrome

Familial Amyloidosis Cutis Dyschromica: a Case Report

Amyloidosis cutis dyschromica (ACD) is a rare form of macular amyloidosis characterized by hypo and hyperpigmented macules. Here we described a 20 year old girl with diffuse hypo and hyperpigmentation since she was four years old. Five other members of her family are also involved. Biopsy of hyperpigmented lesions revealed increase of melanin in the basal layer, pigment incontinence and amorphous eosinophilic masses stained positive with Congo red in the papillary dermis. The histopathologic findings were consistent with amyloidosis cutis dyschromica. Other investigations were normal. Dermatologists should consider amyloidosis cutis dyschromica when visit a patient with diffuse hypo and hyperpigmentation

The interaction between CRY1 Polymorphism and Alternative Healthy Eating Index (AHEI) on cardiovascular risk factors in overweight women and women with obesity: a cross-sectional study

Abstract Background According to some studies, diet can be interaction with CRY1 polymorphism and may be related to obesity and the risk of cardiovascular diseases (CVD). So, this study examined the interaction between CRY1 polymorphism and AHEI on cardiovascular risk factors in overweight women and women with obesity. Methods This cross-sectional study was performed on 377 Iranian women with overweight and obesity aged 18–48(BMI ≥ 25 kg/m2). Dietary intake was evaluated by the use of a food frequency questionnaire (FFQ) with 147 items. The AHEI was calculated based on previous studies. Anthropometric and biochemical measurements were assessed and the bioelectrical impedance analysis method was used for body analysis. The rs2287161 was genotyped by the restriction fragment length polymorphism (PCR-RFLP) method. Objects were divided into three groups based on rs2287161 genotypes. Results Our findings determined that the prevalence of the C allele was 51.9% and the G allele was 48.0%. The mean age and BMI were 36.6 ± 9.1years and 31 ± 4 kg/m2 respectively. After controlling for confounders (BMI, age, total energy intake, and physical activity), this study demonstrated that there was a significant interaction between CC genotype and adherence to AHEI on odds of hyper LDL (OR = 1.94, 95% CI = 1.24–3.05, P for interaction = 0.004), hypertension (OR = 1.80, 95% CI = 1.11–2.93, P for interaction = 0.01) and hyperglycemia (OR = 1.56, 95% CI = 0.98–2.47, P for interaction = 0.05). Conclusions This study indicated that adherence to AHEI can reduce the odds of hyper LDL, hypertension, and hyperglycemia in the CC genotype of rs2287161

Assessment of clinical diagnostic accuracy compared with pathological diagnosis of basal cell carcinoma

Background: Basal cell carcinoma (BCC) is the most common type of skin cancer, afflicting light skin more than dark skin people. This malignancy metastasizes rarely and has unique histological properties. Aims and Objectives: We focused on the accuracy of clinical diagnoses of BCC by specialists. Materials and Methods: Patients′ information for 4-year period between 2007 and 2011 was extracted from files at a Pathology Department. The results were analyzed using the Chi-square method and SPSS software. Results: From 367 referred cases dermatologists diagnosed 41% as direct BCC cases, 43.4% through excluding other skin diseases, 4% incorrectly and 1.11% unidentified. For other specialists (including plastic surgeons, ophthalmologists, general surgeons, and general practitioners) these were respectively 47.8%, 22.4%, 6.3% and 23.5%. Dermatologists had diagnosed 107 cases of all skin diseases as BCC through clinical examination of which 78.5% were correctly and 21.5% incorrectly diagnosed. The same parameters for all other specialists were respectively 77.36% and 22.64%. Diagnostic sensitivity, positive reportability, clinical conjecture indicator (CCI) and clinical diagnostic indicator were respectively 84.4%, 78.5%, 121.5% and 75.6%; whereas for other specialists these indicators were 70 among cases diagnosed by dermatologists as BCC, where pathological results showed other causes. The most common diagnosis by pathologists and other specialists was reported as squamous cell carcinoma (SCC). Among cases not diagnosed by dermatologists as BCC, where pathological results indicated BCC, the most common clinical diagnosis was malignant melanoma by dermatologists and SCC by other specialists. Conclusion: Dermatologists diagnosed BCC with higher sensitivity and positive reportability; also, CCIs and clinical diagnostic correctness was higher among dermatologists. The necessity for consulting with dermatologists and referring all skin diseases samplings to pathologist is thus clearly visible

Evaluation Eucalyptus camaldulensis Contaminations with Cryptococcus gattii in Tehran

Background and Aims: Cryptococcosis is an infection caused by Cryptococcus species. Cryptococcus gattii is mostly isolated from Eucalyptus trees and is acquired via inhalation of basidiospores. The present study was performed to isolate Cryptococcus sp. from Eucalyptus trees and evaluate C. gatti contamination of the Eucalyptus camaldulensis trees in some parks of Tehran and Varamin. Materials and Methods: 88 trees (leaves, stalk, fruit and soil) were collected from different areas of Tehran, Varamin and Shahr Ray in 2014-2015 during spring and fall. Identification of Cryptococcus sp. were performed based on colony color on niger seed agar medium, urease production, india ink test and pseudohyphae formation on corn meal agar with tween 80. Specific differentiation of Cryptococcus sp. were performed using sugar assimilation by API 20C AUX, disk approaches, colony color on Canavanine Glycine Bromothymol Blue and Cycloheximide-Phenol Red Agar medium. Results and Conclusions: 6 out of 88 samples of Eucalyptus trees were identified as Cryptococcus sp. Accordingly, four species were identified as Cryptococcus albidus while species of two other isolates were not detectable by used methods. Although Cryptococcus gattii was not isolated from the collected samples, this does not mean that Eucalyptus trees of Tehran are not contaminated