Experimental Study on Flow and Bank Erosion in Steep and Curved Trapezoidal Channels

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

Logic of alternative-I

This paper aims to construct a logic of alternative-I that provides a proper conceptual framework for talk of possible-I in decision-making context, and thereby solves what we call the paradox of possible-I. The model of our logic, Alt-I model, is an adaptation of N. Belnap’s branching-time model, and the STIT (see to it that) operator defined on the model serves to represent choices and decisions made by actual and counterfactual agents. We conclude this paper by discussing the application of Alt-I model to the case of digital twins, digital copies of a person

N,N'-Diphenylperylene Diimide Functioning as a Sensitizing Light Absorber for Organic Thin-Film Solar Cells

ArticleORGANIC ELECTRONICS. 14(2):464-468 (2013)journal articl

Influence of lifestyle choices on risks of CYP1B1 polymorphisms for prostate cancer.

Cytochrome P450 1B1 (CYP1B1) converts xenobiotics to carcinogens and how lifestyle choices may interact with CYP1B1 polymorphisms and affect prostate cancer risk was assessed. Blood genomic DNA from a Caucasian population was analysed at polymorphic sites of the 5' untranslated region of CYP1B1 using TaqMan genotyping assays. Overall, drinker status and minor alleles at rs2551188, rs2567206 and rs10175368 were associated with prostate cancer. Linkage was observed between rs2551188, rs2567206, rs2567207 and rs10175368, and the G-C-T-G haplotype (major allele at respective sites) was decreased in cancer. Interestingly when classified by lifestyle factors, no associations of genotypes were found for non-smokers and non-drinkers, whereas on the contrary, minor type at rs2567206 and rs10175368 increased and major G-C-T-G decreased risk for cancer among smokers and drinkers. Interestingly, rs2551188, rs2567206 and rs10175368 minor genotypes correlated with increased tissue CYP1B1 as determined by immunohistochemistry. Further, rs10175368 enhanced luciferase activity and mobility shift show stronger binding of nuclear factor for the minor allele. These results demonstrate smoking and alcohol consumption to modify the risks of CYP1B1 polymorphisms for prostate cancer which may be through rs10175368, and this is of importance in understanding their role in the pathogenesis and as a biomarker for this disease