7 research outputs found
Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs
- Publication venue
- Publication date
- 01/01/2005
- Field of study
No full textDrug design for G-protein-coupled receptors by a ligand-based NMR method.
- Author
- Publication venue
- Publication date
- 18/01/2010
- Field of study
No full textAcyl Ureas as Human Liver Glycogen Phosphorylase Inhibitors for the Treatment of Type 2 Diabetes
- Author
- Brunger A. T.
- Brunger A. T.
- Catalyst
- Defossa E.
- Defossa E.
- Defossa E.
- Drueckes P.
- Ekstrom J. L.
- Fischer E. H.
- Gregoriou M.
- Halgren T. A. MMFF VII
- Herling A. W.
- Hoover D. J.
- Jones T. A.
- Kabsch W
- Kristiansen M.
- Kruszynska Y. T.
- Landau B. R.
- Lu Z.
- Martin W. H.
- Mohamadi F.
- Newgard C. B.
- Oikonomakos N. G.
- Oikonomakos N. G.
- Oikonomakos N. G.
- Oikonomakos N. G.
- Otwinowski Z.
- Rath V. L.
- Rath V. L.
- Schoenafinger K.
- Schroth W.
- Schwab D.
- Speziale A. J.
- Speziale A. J.
- SYBYL
- Treadway J. L.
- Weikert R. J.
- Wiley P. F
- Zographos S. E.
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study
No full textStructural basis for GPR40 allosteric agonism and incretin stimulation
- Author
- A Jazayeri
- A Srivastava
- AI Alexandrov
- AS Jensen
- BJ Eastwood
- C Vonrhein
- C Yabuki
- C Zheng
- CF Burant
- CP Briscoe
- D Wootten
- D Zhang
- DC Lin
- E Defossa
- GN Murshudov
- J Luo
- J Lutten
- JA Ballesteros
- JA Barker
- KR Watterson
- L Onsager
- LA Stoddart
- M Caffrey
- M Hauge
- MD Winn
- ML Connolly
- O Moro
- P Emsley
- P Evans
- PR Gerber
- S Edfalk
- SG Rasmussen
- V Poitout
- VB Chen
- W Kabsch
- Y Itoh
- Y Sugimoto
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
No full textCombiphore (Structure and Ligand Based Pharmacophore) - Approach for the Design of GPR40 Modulators in the Management of Diabetes
- Author
- Al-Balas Q.
- Anuradha K. Gajjar
- Bhatt H.
- Cao G.P.
- Chen X.
- Cooke R.M.
- Defossa E.
- Dhoke G.V.
- Goodford P.J.
- Huang D.
- Huang-Sheng L.
- Jain V.
- Kaku K.
- Kaveeshwar S.A.
- Krishna A. Gajjar
- Kumar R.
- Lu H.
- Lu S.
- Lu S.H.
- Ma Y.
- Maganti L.
- Mason J.
- Meganathan C.
- Milligan G.
- Niu M.
- Niu M.M.
- Niu Miaomiao
- Pandey R.
- Pavadai E
- Raj K.K.
- Rollinger JM
- Sahoo G.C.
- Sakkiah S.
- Sakkiah S.
- Sakkiah S.
- Sakkiah S.
- Sakkiah S.Venkatesh
- Sathishkumar N.
- Shahlaei M.
- Singh A.
- Sugunadevi S.
- Takano R.
- Watterson K.R.
- Zahanich I.
- Publication venue
- 'Bentham Science Publishers Ltd.'
- Publication date
- Field of study
No full textPancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis
- Author
- A Dov
- A Gresset
- A Jovic
- A Sassmann
- A Tengholm
- A Varadi
- A Wuttke
- AA Alousi
- AA Gerencser
- AC Kruse
- AD Mancini
- AH Rosengren
- AR Meloni
- AV Smrcka
- B Ahren
- B Ahren
- B Ahren
- B Colsoul
- B Hille
- B Roger
- BE Peercy
- BE Peercy
- BH Falkenburger
- BH Falkenburger
- BH Falkenburger
- BJ Lamont
- C Gonelle-Gispert
- C Hoffmann
- C Schofl
- C Widmann
- CA Syme
- CF Burant
- CH McIntosh
- CJ Barker
- CJ Brinkerhoff
- CM Vines
- CW Dessauer
- CW Lin
- D Delmeire
- D Gautam
- D Heitzler
- D Jacobson
- D Mears
- D Porte Jr
- D Schelshorn
- D Steiner
- D Tornehave
- D Yabe
- DA Fruman
- DA Jacobson
- DE Logothetis
- DJ Drucker
- DM Cooper
- E Cognard
- E Defossa
- E Degerman
- E Heimann
- FM Ashcroft
- FM Ashcroft
- FS Willard
- G Lemon
- G Milligan
- G Pacini
- G Sanchez-Fernandez
- GG Holz
- GG Holz
- GJ Felix-Martinez
- GM Bokoch
- GM Whitaker
- H Kaneto
- H Tsuga
- H Yamazaki
- HC Fehmann
- HG Holzhutter
- HM Sauro
- I Azpiazu
- I Ruiz de Azua
- II Moraru
- J de Heer
- J Gromada
- J Gromada
- J Hamann
- J Jakubik
- J Molina
- J Qian
- J Selway
- J Wagner
- JC Henquin
- JC Henquin
- JC Miguel
- JJ Holst
- JJ Saucerman
- JL Dyer
- JL Selway
- JM Guettier
- JP Vilardaga
- JP Vilardaga
- JW Putney
- K Fujiwara
- K Nagasumi
- K Nakajima
- KC Kong
- L Shu
- L Storlien
- LA Swayne
- LD Shea
- LE Fridlyand
- LE Fridlyand
- LE Fridlyand
- LE Fridlyand
- LE Fridlyand
- LE Fridlyand
- LE Fridlyand
- LE Fridlyand
- Leonid E. Fridlyand
- LH Xie
- LL Baggio
- Louis H. Philipson
- LR Landa Jr
- M Dolz
- M Ferdaoussi
- M Kim
- M Kruse
- M Pan
- M Prentki
- M Raoux
- M Seed Ahmed
- MA Nauck
- MA Nauck
- MA Ravier
- MB Wheeler
- MC Garcia
- ME Doyle
- ME Kimple
- MG Latour
- MG Pedersen
- MJ Berridge
- MJ Berridge
- MJ Kim
- MS Islam
- MS Winzell
- N Li
- N Ziegler
- NA Tamarina
- NA Tamarina
- NA Tamarina
- NG Morgan
- NJ Pyne
- NM Doliba
- NM Doliba
- NM Doliba
- NM Whalley
- O Dyachok
- O Dyachok
- P Beguin
- P Cazzaniga
- P Gilon
- P Gilon
- P Gilon
- P Hein
- P Hein
- P Nadkarni
- P Rorsman
- P Rorsman
- P Smolen
- PE Light
- PJ Woodroffe
- PJ Woolf
- PM Dean
- R Bertram
- R Bertram
- R Ekanger
- R Fiume
- R Jain
- R Nakashima
- R Seifert
- RK Benninger
- RK Sunahara
- RM Luik
- RR Gainetdinov
- RV Iancu
- S Amisten
- S Calanna
- S Del Guerra
- S Gopel
- S Jain
- S Mohammad
- S Rajan
- S Rajan
- S Schnell
- S Seino
- S Seino
- S Seino
- S Srinivasan
- S Thore
- S Thore
- S Vollert
- SA Hinke
- SE Kahn
- SG Straub
- SK Shenoy
- SL Shyng
- SN Sreenath
- SR Hoare
- T Baukrowitz
- T Haga
- T Just
- T Kitaguchi
- T Liang
- T Manninen
- T MH Hashimoto
- T Tsalkova
- T Yada
- Tao Cai
- TK Harden
- TN Litvin
- U Klingmuller
- V Fagerholm
- V Sunil
- V Vanderheyden
- VA Gault
- WP Hausdorff
- WS Zawalich
- X Jia
- XQ Dai
- Y Itoh
- Y Okuma
- Y Seino
- Y Suzuki
- Y Takeda
- Y Tian
- YJ Zhou
- Z Xia
- ZF Kang
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
No full textG protein-coupled receptors as targets for anti-diabetic therapeutics
- Author
- A Bonnefond
- A Chawla
- A Claing
- A Hicks
- A Hirasawa
- A Hirasawa
- A Ichimura
- A Inoue
- A Kavelaars
- A Peters
- A Périz
- A Secher
- A Stonehouse
- A Vella
- A Zernecke
- AD Lucas
- AD Mancini
- AD Mancini
- AE Cardona
- AM Johnson
- AR Saltiel
- AS Barnes
- AT Hill
- AT Suckow
- B Ahren
- B Ahren
- B Samuelsson
- BD Hudson
- BJ Lamont
- BK Kobilka
- BM Moran
- C Combadiere
- C Gotoh
- C Hundhausen
- C Orskov
- CA Haskell
- CF Burant
- CF Deacon
- CJ Nolan
- CM Yates
- CN Lumeng
- CP Briscoe
- CP Tan
- D Dicker
- D Ma
- D Sirois-Gagnon
- DA Raptis
- DA Winer
- Da Young Oh
- DC Lin
- DC Lin
- DE Cintra
- DH van Raalte
- DJ Drucker
- DJ Drucker
- DJ Drucker
- DT Stein
- DX Brown
- DY Oh
- E Christiansen
- E Defossa
- E Flodgren
- EJ Freyse
- EM Migoya
- F Reimann
- F Tacke
- G Folco
- G Grunberger
- GC Yaney
- GG Sokos
- H Kim
- H Lan
- H Lan
- H Shapiro
- H Xu
- H Yashiro
- HA Overton
- HC Fehmann
- HE Parker
- HJ Showell
- HM Yusof
- HS Hansen
- J Buteau
- J Cuthbertson
- J Dupuis
- J Luo
- J Zhang
- JA Ehses
- JA Rankin
- JB Buse
- Jerrold M. Olefsky
- JJ Holst
- JJ Meier
- JM Olefsky
- JR Unger
- JW Sijben
- K Eguchi
- K Fujiwara
- K Kaku
- K Kazafeos
- K Nagasumi
- K Nakamoto
- KB Hansen
- KC Baynes
- KC de Git
- KE Bornfeldt
- KJ Garton
- KL Pierce
- KM Beeh
- L Gronke
- L Hansen
- L Lauffer
- L Wang
- L Wellhauser
- LA Nikolaidis
- LA Stoddart
- LS Doshi
- LS Sorensen
- LS Sorensen
- M Berger
- M Chen
- M Cnop
- M Ferdaoussi
- M Kalis
- M Kebede
- M Kebede
- M Milanski
- M Peters-Golden
- M Prentki
- M Spite
- M Stumvoll
- M Tzefos
- M Zander
- MA McArdle
- ME Cerf
- ME Doyle
- MG Latour
- MM Yore
- MY Donath
- N Negoro
- N Sonoda
- O Radmark
- P Li
- P Li
- P Montuschi
- P Richards
- P Stranges
- PA Read
- PC Calder
- PV Afonso
- Q Wang
- R Farre
- R Shah
- R Vettor
- R Wagner
- RA Dixon
- RA Hall
- RM Jones
- RN Burns
- RN Burns
- RP Robertson
- RR Gerner
- S Brunton
- S Edfalk
- S Madsbad
- S Nancey
- S Sisley
- S Talukdar
- S Xu
- SE Kahn
- SE Shoelson
- SJ Watson
- SM Proudman
- SP Weisberg
- SR Crespin
- SW Crooks
- T Alquier
- T Aoyama
- T Imai
- T Soga
- T Soga
- T Vilsboll
- T Yokomizo
- T Yokomizo
- U Gether
- U Shah
- V Katritch
- V Poitout
- V Wieser
- VA Fonseca
- VT Samuel
- W Tian
- WG Tong
- X Li
- Y Imai
- Y Itoh
- Y Li
- Y Liu
- Y Oh da
- Y Tsujihata
- Y Williams-Bey
- Y Xiong
- Y Yan
- YS Lee
- Z Liu
- ZL Chu
- ZL Chu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
No full text
