Testing Efficacy in Determination of Recurrent Supraventricular Tachycardia among Subjectively Symptomatic Children Following “Successful” Ablation

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108265/1/pace12373.pd

Musculoskeletal manifestations in type 2 diabetes mellitus

Background: Musculoskeletal complications of diabetes have been generally ignored and poorly treated as compared to other complications. Hence we carried out this study to find the prevalence of musculoskeletal manifestations in type II diabetes mellitus and its correlation with age, BMI, duration of diabetes, and control of diabetes.Methods: 100 consecutive patients of type II diabetes were studied. Duration of diabetes, control of diabetes, and any musculoskeletal complaints were noted. Complete examination with special reference to BMI, waist circumference and waist hip ratio was done. Fasting and postprandial blood sugar and HbA1c was estimated. Correlation of musculoskeletal manifestations with age, BMI, duration of diabetes, and control of diabetes was evaluated and statistical analysis was done.Results: Study shows that the prevalence of musculoskeletal manifestations was 42%. Difficulty with stairs (73 cases) and joint pain (87cases) were the commonest difficulties patients experienced. Most common affected joint was shoulder joint (56%). Adhesive capsulitis (28 cases), tendonitis (15 cases), limited joint mobility (3 cases) were commonest musculoskeletal manifestations. There was a statistically significant positive correlation between musculoskeletal manifestations and age (odds ratio: 4.4), BMI (odds ratio: 9.6), and control of diabetes (odds ratio: 2.61). There was a positive correlation between duration of diabetes and the presence of musculoskeletal manifestations; however it was not statistically significant.Conclusions: Musculoskeletal manifestations are frequent in Type 2 diabetics and have a positive correlation with age, duration of diabetes, control of diabetes, and BMI

ELECTROCHEMICAL BEHAVIOR OF XANTHENE FOOD DYE ERYTHROSINE AT GLASSY CARBON ELECTRODE AND ITS ANALYTICAL APPLICATIONS

Erythrosine is a xanthene food dye used in the food industries to enhance the appearance of the food. The electrochemical behavior of erythrosine at glassy carbon electrode was investigated by cyclic and differential pulse voltammetry. The oxidation peak of erythrosine was observed in phosphate buffer of pH 5.0. The influence of different pH, scan rate and concentration were evaluated. The probable reaction mechanism involved in the oxidation of erythrosine was also proposed. Differential pulse voltammetric method with good precision and accuracy was developed for the determination of erythrosine dye in real samples. The peak currents were found to be linearly dependent on the concentration range of 1 x 10-5 to 6 x 10-4 M. The limit of detection (LOD) and limit of quantification (LOQ) were noticed to be 1.9 x 10-7 and 6.6 x 10-7 M respectively

Determination of the trape depth of (ZnS) 1-x (MnTe)X Using theromoluminescence.

Thermoluminescence (TL) is a thermally stimulated light emission following the removal of excitation from an insulator or semiconductor. For luminescence emission,excitation is provided by irradiating the sample with X-ray or other ionizing radiation like α,β and ÎŽ –ray.  It should be noted that once heated to excite the light emission, the material can not be made to emit the thermoluminescence again by simply cooling the specimen and reheating

Wireless Multichannel Multipoint Broadcast Service for Mobile Stations

In wireless Multicast Broadcast Service (MBS), the common channel is used to multicast the MBS content to the Mobile Stations (MSs) on the MBS calls within the coverage area of a Base Station (BS), which causes interference to the dedicated channels serving the traditional calls, and degrades the system capacity. The MBS zone technology is proposed in Mobile Communications Network (MCN) standards to improve system capacity and reduce the handoff delay for the wireless MBS calls. In the MBS zone technology, a group of BSs form an MBS zone, where the macro diversity is applied in the MS, the BSs synchronize to transmit the MBS content on the same common channel, interference caused by the common channel is reduced, and the MBS MSs need not perform handoff while moving between the BSs in the same MBS zone. However, when there is no MBS MS in a BS with the MBS zone technology, the transmission on the common channel wastes the bandwidth of the BS. It is an important issue to determine the condition for the MBS Controller (MBSC) to enable the MBS zone technology by considering the Quality of Services (QoS) for traditional calls and MBS calls are used to reduce the dependency over the common channel and also it is going to reduce the delay over the network. By enabling Dynamic Channel Allocation (DCA) and Enhance Dynamic Channel Allocation (EDCA) we are going to overcome these problems

Wireless Multichannel Multipoint Broadcast Service for Mobile Stations

In wireless Multicast Broadcast Service (MBS), the common channel is used to multicast the MBS content to the Mobile Stations (MSs) on the MBS calls within the coverage area of a Base Station (BS), which causes interference to the dedicated channels serving the traditional calls, and degrades the system capacity. The MBS zone technology is proposed in Mobile Communications Network (MCN) standards to improve system capacity and reduce the handoff delay for the wireless MBS calls. In the MBS zone technology, a group of BSs form an MBS zone, where the macro diversity is applied in the MS, the BSs synchronize to transmit the MBS content on the same common channel, interference caused by the common channel is reduced, and the MBS MSs need not perform handoff while moving between the BSs in the same MBS zone. However, when there is no MBS MS in a BS with the MBS zone technology, the transmission on the common channel wastes the bandwidth of the BS. It is an important issue to determine the condition for the MBS Controller (MBSC) to enable the MBS zone technology by considering the Quality of Services (QoS) for traditional calls and MBS calls are used to reduce the dependency over the common channel and also it is going to reduce the delay over the network. By enabling Dynamic Channel Allocation (DCA) and Enhance Dynamic Channel Allocation (EDCA) we are going to overcome these problems

Abiotrophia Endocarditis in Children with No Underlying Heart Disease: A Rare but a Virulent Organism

Infective endocarditis is extremely rare in children with structurally normal hearts. The most common etiological agents are staphylococcal and streptococcal species. Nutritionally variant streptococci also classified as A biotrophia species are a group of fastidious organisms that account for only 5% to 6% of all cases of culture‐negative infective endocarditis. Only seven cases of A biotrophia infective endocarditis have been previously reported in children with no underlying structural heart disease. We report two cases of A biotrophia infective endocarditis in children without any predisposing factors. Both patients presented with nonspecific symptoms leading to delay in diagnosis. While bacteriological clearance was achieved in both cases, both had a complicated course including development of brain mycotic aneurysms, splenic infarction, renal failure, and irreversible damage to the mitral valve. Both patients required surgical removal of the native mitral valve and replacement. We also present review of seven cases with similar diagnosis published previously in literature and highlight important differences. Our cases highlight special challenges in management of A biotrophia endocarditis in pediatric patients. As the organism may not be isolated in routine culture media, may present with atypical clinical symptoms and may have a complicated course even without antibiotic failure, a high index of suspicion should be maintained in children with subacute symptoms even with no underlying structural cardiac disease.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108296/1/chd12095.pd

PROTEINACEOUS COMPOUNDS FROM FRAGARIA ANANASSA FRUIT ATTENUATES PARAQUAT INDUCED PARKINSON LIKE LOCOMOTOR AND MITOCHONDRIAL ALTERATIONS IN ZEBRAFISH

Objectives: To assess the Parkinson like locomotor and mitochondrial alterations, associated with the exposure of paraquat (PQ), in vivo preventive effect of proteinaceous compounds extracted from Fragaria ananassa fruit (FA-D) against mitochondrial dysfunction induced by paraquat in zebra fish using brain mitochondria.Methods: Parkinson like locomotor and mitochondrial alterations were resulted by intra peritoneal administration of 55 mM PQ alternatively for a period of 7 days. The water soluble proteinaceous compounds from Fragaria ananassa fruit were obtained by Ammonium sulphate fractionation. The molecular weight of FA-D fraction was determined by SDS-PAGE and we found three distinct bands at 20.0 kDa, 17.0 kDa and 14.4.0 kDa bands respectively. The in vitro antioxidant activity and the in vivo preventive effect of FA-D against PQ induced Parkinsonian symptoms was evaluated by different assay systems viz., in vitro: radical scavenging activity by DPPH reaction and in vivo: locomotion, dopamine levels, complex-I activity, mitochondrial ROS levels, cytochrome c release and mitochondrial morphology.Results: The results show that paraquat altered locomotor activity and increased dopamine levels. Mitochondria isolated from paraquat treated zebrafish showed a marked inhibition of complex-I activity, increase in mitochondrial reactive oxygen species (mt ROS) and cytochrome c release and disintegration of mitochondrial structure. Treatment of 0.25 mg/kg body weight of FA-D fraction once in alternative days, for 5 days subsequent to the administration of PQ alternatively for a period of 7days, substantially reduced mt ROS levels and markedly restored the complex-I activity, cytochrome c release and mitochondrial morphology.Conclusion: The results strongly suggest that proteinaceous compounds from Fragaria ananassa fruit recuperate paraquat induced Parkinsonian like symptoms by protecting the mitochondria.Â

Effect of antenatal corticosteroids on neonatal outcome in term elective caesarean section: a randomised controlled trial

Background: Infants born at term by elective caesarean section are more likely to develop respiratory morbidity than infants born vaginally. Prophylactic corticosteroids in singleton preterm pregnancies accelerate lung maturation and reduce the incidence of respiratory complications. Thus, the aim of this randomized controlled trial was to assess the effect of antenatal corticosteroids on neonatal outcome among term pregnant women undergoing elective caesarean section.Methods: It was an open labelled randomized controlled trial conducted among women with term pregnancy of 37-38+6 weeks and planned for caesarean section at term and who were willing to participate in the study. We randomized 50 pregnant women into intervention group which received antenatal corticosteroids in the form of injection dexamethasone 12 mg IM, 4 doses at 12 hourly intervals before term elective caesarean section and 50 pregnant women into control group which did not receive antenatal corticosteroid. Fetal outcomes were compared in both groups after caesarean section. Data were analysed using SPSS vs.20.Results: Nearly half (54%) of pregnant women belonged age group of 21-25 years and majority (58%) of pregnant women belonged to 38-39 weeks of gestation. Out of 50 pregnant women in intervention group, only two percent neonates developed RDS, four percent neonates developed transient tachypnea of neonate (TTN) and six percent neonates required NICU admission which was lower than control group. However, difference between fetal outcomes in intervention and control group was not statistically significant (p>0.05).Conclusions: Administration of prophylactic antenatal corticosteroids before 48 hours of elective term caesarean section does not have impact on fetal outcome in our study