Flowchart demonstrating the screening process of papers in the systematic review.

<p>Inclusions and exclusions are shown at each stage.</p

Conceptual model of stroke treatment burden.

<p>The arrows represent the possible pathways between components that stroke patients may follow. The ‘enacting management strategies’ component has four subcomponents.</p

A summary of the quality appraisal of included studies [50].

<p>Each study was appraised using the questions shown in the table. The number of studies with the answers ‘yes’, ‘no’, or ‘unclear’ are shown for each question.</p

Treatment burden identified from the literature.

<p>A taxonomy of treatment burden in stroke, grouped within categories that correspond to the conceptual model of treatment burden shown in <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001473#pmed-1001473-g002" target="_blank">Figure 2</a>.</p