About Time: Master Scheduling and Equity

Master schedules are used to structure time, people, resources, and space within a school. This report provides school and district leaders advice about how to use the master schedule to advance equity in their communities. It illuminates ways the schedule can both undermine and advance equity and provides a framework to help schools and districts pivot from technical to strategic scheduling to expand access and opportunity for all student

A molecular atlas of cell types and zonation in the brain vasculature

Cerebrovascular disease is the third most common cause of death in developed countries, but our understanding of the cells that compose the cerebral vasculature is limited. Here, using vascular single-cell transcriptomics, we provide molecular definitions for the principal types of blood vascular and vessel-associated cells in the adult mouse brain. We uncover the transcriptional basis of the gradual phenotypic change (zonation) along the arteriovenous axis and reveal unexpected cell type differences: a seamless continuum for endothelial cells versus a punctuated continuum for mural cells. We also provide insight into pericyte organotypicity and define a population of perivascular fibroblast-like cells that are present on all vessel types except capillaries. Our work illustrates the power of single-cell transcriptomics to decode the higher organizational principles of a tissue and may provide the initial chapter in a molecular encyclopaedia of the mammalian vasculature.Peer reviewe

About Time: Master Scheduling and Equity

Master schedules are used to structure time, people, resources, and space within a school. This report provides school and district leaders advice about how to use the master schedule to advance equity in their communities. It illuminates ways the schedule can both undermine and advance equity and provides a framework to help schools and districts pivot from technical to strategic scheduling to expand access and opportunity for all student

Future Science Prospects for AMI

The Arcminute Microkelvin Imager (AMI) is a telescope specifically designed for high sensitivity measurements of low-surface-brightness features at cm-wavelength and has unique, important capabilities. It consists of two interferometer arrays operating over 13.5-18 GHz that image structures on scales of 0.5-10 arcmin with very low systematics. The Small Array (AMI-SA; ten 3.7-m antennas) couples very well to Sunyaev-Zel'dovich features from galaxy clusters and to many Galactic features. The Large Array (AMI-LA; eight 13-m antennas) has a collecting area ten times that of the AMI-SA and longer baselines, crucially allowing the removal of the effects of confusing radio point sources from regions of low surface-brightness, extended emission. Moreover AMI provides fast, deep object surveying and allows monitoring of large numbers of objects. In this White Paper we review the new science - both Galactic and extragalactic - already achieved with AMI and outline the prospects for much more.Comment: 20 pages, 11 figures; white paper. Revised author list, section IB, section IIIC2, reference