688 research outputs found
142: Low dose thalidomide maintenance in myeloma patients after autologous stem cell transplantation
Large-scale Oscillation of Structure-Related DNA Sequence Features in Human Chromosome 21
Human chromosome 21 is the only chromosome in human genome that exhibits
oscillation of (G+C)-content of cycle length of hundreds kilobases (500 kb near
the right telomere). We aim at establishing the existence of similar
periodicity in structure-related sequence features in order to relate this
(G+C)% oscillation to other biological phenomena. The following quantities are
shown to oscillate with the same 500kb periodicity in human chromosome 21:
binding energy calculated by two sets of dinucleotide-based thermodynamic
parameters, AA/TT and AAA/TTT bi-/tri-nucleotide density, 5'-TA-3' dinucleotide
density, and signal for 10/11-base periodicity of AA/TT or AAA/TTT. These
intrinsic quantities are related to structural features of the double helix of
DNA molecules, such as base-pair binding, untwisting/unwinding, stiffness, and
a putative tendency for nucleosome formation.Comment: submitted to Physical Review
Two-atom dark states in electromagnetic cavities
The center-of-mass motion of two two-level atoms coupled to a single damped
mode of an electromagnetic resonator is investigated. For the case of one atom
being initially excited and the cavity mode in the vacuum state it is shown
that the atomic time evolution is dominated by the appearance of dark states.
These states, in which the initial excitation is stored in the internal atomic
degrees of freedom and the atoms become quantum mechanically entangled, are
almost immune against photon loss from the cavity. Various properties of the
dark states within and beyond the Raman-Nath approximation of atom optics are
worked out.Comment: 8 pages, 4 figure
Sympathetic Cooling of Trapped Cd+ Isotopes
We sympathetically cool a trapped 112Cd+ ion by directly Doppler-cooling a
114Cd+ ion in the same trap. This is the first demonstration of optically
addressing a single trapped ion being sympathetically cooled by a different
species ion. Notably, the experiment uses a single laser source, and does not
require strong focusing. This paves the way toward reducing decoherence in an
ion trap quantum computer based on Cd+ isotopes.Comment: 4 figure
Cooling the Collective Motion of Trapped Ions to Initialize a Quantum Register
We report preparation in the ground state of collective modes of motion of
two trapped 9Be+ ions. This is a crucial step towards realizing quantum logic
gates which can entangle the ions' internal electronic states. We find that
heating of the modes of relative ion motion is substantially suppressed
relative to that of the center-of-mass modes, suggesting the importance of
these modes in future experiments.Comment: 5 pages, including 3 figures. RevTeX. PDF and PostScript available at
http://www.bldrdoc.gov/timefreq/ion/qucomp/papers.htm . final (published)
version. Eq. 1 and Table 1 slightly different from original submissio
q-Generalization of the inverse Fourier transform
A wide class of physical distributions appears to follow the q-Gaussian form,
which plays the role of attractor according to a Central Limit Theorem
generalized in the presence of specific correlations between the relevant
random variables. In the realm of this theorem, a q-generalized Fourier
transform plays an important role. We introduce here a method which univocally
determines a distribution from the knowledge of its q-Fourier transform and
some supplementary information. This procedure involves a recently
q-generalized Dirac delta and the class of functions on which it acts. The
present method conveniently extends the inverse of the standard Fourier
transform, and is therefore expected to be very useful in the study of many
complex systems.Comment: 6 pages, 3 figures. To appear in Physics Letters
All-optical ion generation for ion trap loading
We have investigated the all-optical generation of ions by photo-ionisation
of atoms generated by pulsed laser ablation. A direct comparison between a
resistively heated oven source and pulsed laser ablation is reported. Pulsed
laser ablation with 10 ns Nd:YAG laser pulses is shown to produce large calcium
flux, corresponding to atomic beams produced with oven temperatures greater
than 650 K. For an equivalent atomic flux, pulsed laser ablation is shown to
produce a thermal load more than one order of magnitude smaller than the oven
source. The atomic beam distributions obey Maxwell-Boltzmann statistics with
most probable speeds corresponding to temperatures greater than 2200 K. Below a
threshold pulse fluence between 280 mJ/cm^2 and 330 mJ/cm^2, the atomic beam is
composed exclusively of ground state atoms. For higher fluences ions and
excited atoms are generated.Comment: 7 pages, 9 figure
Destabilization of dark states and optical spectroscopy in Zeeman-degenerate atomic systems
We present a general discussion of the techniques of destabilizing dark
states in laser-driven atoms with either a magnetic field or modulated laser
polarization. We show that the photon scattering rate is maximized at a
particular evolution rate of the dark state. We also find that the atomic
resonance curve is significantly broadened when the evolution rate is far from
this optimum value. These results are illustrated with detailed examples of
destabilizing dark states in some commonly-trapped ions and supported by
insights derived from numerical calculations and simple theoretical models.Comment: 14 pages, 10 figure
Observation of single collisionally cooled trapped ions in a buffer gas
Individual Ba ions are trapped in a gas-filled linear ion trap and observed
with a high signal-to-noise ratio by resonance fluorescence. Single-ion storage
times of ~5 min (~1 min) are achieved using He (Ar) as a buffer gas at
pressures in the range 8e-5 - 4e-3 torr. Trap dynamics in buffer gases are
experimentally studied in the simple case of single ions. In particular, the
cooling effects of light gases such as He and Ar and the destabilizing
properties of heavier gases such as Xe are studied. A simple model is offered
to explain the observed phenomenology.Comment: 5 pages, 4 figures, accepted for publication in Phys. Rev. A. Minor
text and figure change
- …