Ataques Especulativos: Un Enfoque de Incertidumbre e Información

Durante la década pasada hemos presenciado una proliferación de crisis cambiarias, tanto en Asia como en Europa y Latinoamérica, acompañada de abundante literatura acerca del tema. Es aceptado que, cuando las políticas monetaria y fiscal no son congruentes entre sí, habrá una crisis de balanza de pagos. La literatura reciente ha avanzado en varias direcciones para explicar los mecanismos de propagación de una crisis, que aplican aún cuando la política del gobierno es sostenible. No obstante, este tipo de modelos explica escasamente la iniciación de un ataque. El objetivo de este artículo es dar una explicación tentativa a esa iniciación. Se presenta un modelo donde la obtención de información es crucial para el inversionista y ésta se deteriora con el tiempo; en este marco, el ataque especulativo es un comportamiento óptimo para un inversionista que tenga la capacidad de llevarlo a cabo. Del modelo puede concluirse, entre otras cosas, que existe una relación inversa entre la frecuencia y la profundidad de los ataques. Además, el tamaño del agente relativo a la economía y la fuerza del efecto manada afectan de manera importante los costos del ataque y, de esta forma, afectan también la vulnerabilidad de cada economía a sufrir ataques especulativos.

Assessing Child Obesity and Physical Activity in a Hard-to-Reach Population in California's Central Valley, 2012-2013.

IntroductionIn California's agricultural Central Valley, the rate of childhood obesity is higher than the national average. Adequate physical activity contributes to obesity prevention and its assessment is useful to evaluate the impact of interventions.MethodsNiños Sanos, Familia Sana (Healthy Children, Healthy Family [NSFS]) uses community-based participatory research to implement an intervention program to reduce childhood obesity among people of Mexican origin in the Central Valley. Anthropometric measurements were conducted on more than 650 children enrolled in NSFS. Physical activity data from a subgroup of children aged 4 to 7 years (n = 134) were collected via a wearable accelerometer.ResultsChildren were classified on the basis of age and sex-adjusted body mass index as healthy weight (57.7%); overweight (19.3%), or obese (23%). Logistic regression showed that moderate to vigorous physical activity (MVPA) was associated with a child's likelihood of having a healthy BMI (odds ratio: 1.03; 95% CI, 1.01-1.05; P = .017).ConclusionNSFS's community-based participatory approach resulted in successful use of a commercial electronic device to measure physical activity quantity and quality in this hard-to-reach population. Promotion of adequate daily MVPA is an appropriate and necessary component of NSFS's childhood obesity prevention strategy

Ensuring image integrity in the digital age

FEBS Open Bio and our fellow FEBS Press journals have a strong commitment to maintaining the integrity of the scientific literature. The life sciences, in particular, are suffering from an ongoing reproducibility crisis, and this may in part be fuelled by mistakes, manipulation or outright fabrication of the presented data. We were recently made aware of several articles published in FEBS Open Bio that appear to contain full or partial duplications of images from other published articles in a different scientific context. In most of these cases, the duplications were taken from previously published papers. After thorough investigation and subsequent discussion within FEBS Press and with Wiley's Integrity in Publishing Group, we have retracted most of these articles

Ten years of FEBS Open Bio

This month, FEBS Open Bio celebrates its 10th birthday. To celebrate the journal's first decade, we present this special anniversary issue, comprised of editorials, reviews, and research articles especially commissioned for the occasion. In this introductory editorial, we invite the reader to join us as we reminisce over the journal's past, celebrate its present, and look forward to its future

Entering the second decade: FEBS Open Bio in 2022

FEBS Open Bio continues to go from strength to strength, with 2021 perhaps marking its most exciting year. In this Editorial, the Editor-in-Chief Miguel A. De la Rosa looks back at all the new developments of 2021 and forecasts the outlook for 2022

PND30 Cost Analysis of Glatiramer Acetate Versus Fingolimod for the Treatment of Patients With Relapsing-Remitting Multiple Sclerosis in Spain

BACKGROUND: Fingolimod is an innovative drug with a significant budget impact in the treatment of MS in Spain. The aim of this study was to calculate the direct cost comparison of glatiramer acetate and fingolimod for the treatment of patients with relapsing-remitting multiple sclerosis (RRMS) in Spain. METHODS: A cost analysis model was developed to compare glatiramer acetate and fingolimod, based on a 1-year time horizon. In addition to the pharmacological costs, resource use was estimated for glatiramer acetate (1 hour of training with nursing staff in self-injection techniques for subcutaneous administration) and fingolimod (vaccination for varicella-zoster virus in 5% of patients, 3 complete blood counts per year, 3 ophthalmology visits for prevention of macular edema, 3 transaminase tests to monitor liver function, and cardiovascular monitoring consisting of 1 ECG before the first fingolimod dose and at 6 hours; 1 day outpatients-hospital visit for cardiological monitoring during 6 hours on the day of the first fingolimod dose, with follow-up of blood pressure and heart rate every hour). The pharmacological costs were calculated based on the ex-factory price of the drugs evaluated, using the doses recommended in the respective Summary of Products Characteristics (SmPC). Total invoicing volume was discounted by 7.5%, as laid down in Spanish Royal Decree 8/2010. Unit costs were obtained from the e-Salud database and the drug catalog. Costs in the model are expressed in €2012. RESULTS: The cost of annual treatment was €9,439.42 for glatiramer acetate and €19,602.18 for fingolimod, yielding a cost difference of €10,162.76. Assuming a fixed budget of €100,000.00, approximately 10 patients could be treated with glatiramer acetate, compared to 5 with fingolimod. CONCLUSIONS: Fingolimod therapy requires twice the investment as glatiramer acetate

Switching of Magnetic Moments of Nanoparticles by Surface Acoustic Waves

We report evidence of the magnetization reversal in nanoparticles by surface acoustic waves (SAWs). The experimental system consists of isolated magnetite nanoparticles dispersed on a piezoelectric substrate. Magnetic relaxation from a saturated state becomes significantly enhanced in the presence of the SAW at a constant temperature of the substrate. The dependence of the relaxation on SAW power and frequency has been investigated. The effect is explained by the effective ac magnetic field generated by the SAW in the nanoparticles.Comment: Accepted in Europhysics Letter

Contribución al estudio del citodiagnóstico y tratamiento de la tuberculosis pulmonar

El verso de las h. en blanco. Tesis de doctorado leída en la Universidad Central el 6 de abril de 1904.Universidad Central (Madrid)TRUEProQuestpu