Mechanical Stress as a Cause of Hidradenitis Suppurativa: A Lesson from a Patient with a Monster Hernia

No abstract available </p

Misdiagnosed atopic dermatitis: Case report

We report a case of a healthy 12-year-old female, who presented a large eczema of the face for more than 2 months. After microbiologic examination a diagnosis of atopic dermatitis with Staphylococcus aureus colonization was done. A combined topical corticosteroid- oral antibiotics therapy allowed to obtain a good clinical response. There was no recurrence 6 months after the treatment. Our case highlights that sometimes staphylococcal skin infections affecting atopic dermatitis can lead to misdiagnosis

Mechanical Stress as a Cause of Hidradenitis Suppurativa: A Lesson from a Patient with a Monster Hernia

No abstract available </p

Salicylic acid for the treatment of melasma: new acquisitions for monitoring the clinical improvement.

OBJECTIVE: The Melasma Area and Severity Index (MASI) and the Melasma Severity Score (MSS) are calculated on the basis of only a subjective clinical assessment. This raises the need to have an objective score, uniform in the evaluation by different clinicians. The purpose of this study was to establish if the images by Canfield Reveal Imager can be correlated to MASI score to better evaluate the clinical efficacy of salicylic acid 33% peeling in the treatment of melasma respect to the clinical observation. METHODS: The study was a voluntary observational study. Twenty female patients affected with melasma, aged between 30 and 60 years, were included in the study. Treatment with salicylic acid 33% was performed once a month, for a total of four times. The dermatologist (Doc A) examined each patient's melasma areas using MASI score, at the face-to-face observation and at Reveal images evaluation during the first (T0) and the end point time (T4). Digital photographs were also evaluated by another experienced dermatologist (Doc B), who has never seen clinically the patients before and who evaluated MASI score by Reveal images at time T0 and T4. RESULTS: Student's t-test and linear regression test were performed, showing statistically significant values comparing MASI score obtained by digital photo and MASI score obtained clinically. CONCLUSION: The monitoring of the improvement by Reveal images can optimize the treatment approach and the efficacy of same dermocosmetics procedures can be revised following standard criteria

CITTÀ INCLUSIVE PER COMUNITÀ INTERCULTURALI. ESPERIENZE EUROPEE

The multicultural city is one of the major issues within the political Agenda as well as one of the prominent research topics, also due to the recent increasing of migratory flows throughout Europe. Within this framework, urban policies have been included in decisionmaking processes regarding cultural inclusion and social cohesion: cities have been considered the outpost of cultural diversities and dialogues. According to this scenario, the research focuses on European initiatives at urban level oriented at increasing the cultural inclusiveness. Challenges, issues and opportunities have been explored from a specific perspective: how local authorities and communities deal with this challenge in terms of spatial and social equity. By applying a case study approach, bottom up experiences, social innovation practices, community-led initiatives as well as traditional top down projects dedicated to the multicultural city have been collected and analyzed. The results of the survey show a scenario in which both bottom up initiatives and community engagement processes can be catalyst of a self-sustaining intercultural development.DOI: http://dx.medra.org/10.19254/LaborEst.14.0

Natural Commercial Centers: Regeneration Opportunities and Urban Challenges

In the history of European cities, public spaces always played a pivotal role, representing key places for developing social interactions and for enhancing the sense of community. Squares, commercial streets, market places as well as traditional retail and art-and-crafts areas can be considered the core of the city. The social, economic and demographic crisis and the loss of cultural identity has affected the capacity of attraction of local small retailers, giving the floor to the aggressive strategies of suburban shopping malls, centers, arcades or precinct, forming a complex of shops, movie theaters, restaurants and food courts with interconnecting walkways [. Typical expressions of a globalized economy, the different categories of suburban shopping mall have transformed behaviors and paths at a large scale [. One consequences can be identified in the loss of traditional commercial activities within the city centre, producing a situation of urban decline, mirrored by the impoverishment of public spaces [[. This paper suggests that, by activating the existing cultural and socio-economic capital it is possible to undertake a successful regeneration process based on a participative approach and on public and private integrated tools. By focussing on the experience of the Centri Commerciali Naturali (Natural Commercial Centres) established in Italy as partnership between Municipalities, cultural operators, public services providers and associations of shops owners to exploit the commercial activities in the historical centers the ongoing research is oriented to explore successful experiences of private-public partnership to be implemented in a regeneration process of areas traditionally dedicated to retail and art-and-craft small enterprises. The paper discusses the potentiality and the criticism of the NCC as engine for the redevelopment and regeneration of the inner city abandoned retail areas. In so doing, the experience developed in Campania (Southern Italy) will be analyzed in order to show how the activation of the social capital within the framework of the CCN could contribute in renovating the traditional commercial identity of the area, supporting the public spaces regeneration process. This paper aspires to offer useful insights to all those policy makers, city managers and planners who seek to revitalise traditional market areas in European city centres

Statistical image processing for the detection of dermoscopic criteria

An image based system implementing a well-known diagnostic method is disclosed for the automatic detection of melanomas as support to clinicians. The software procedure is able to recognize automatically the skin lesion within the digital image, measure morphological and chromatic feature, carry out a suitable classification for the detection of structural dermoscopic criteria provided by the 7-Point Check List. Experimental results about the adoption of statistical techniques applied to the border detection, feature extraction and classification as well as the resulting diagnostic score are described with reference to a large image set. Copyright © 2011 by the International Measurement Confederation (IMEKO) All rights reserved

The effect of aminolevulinic acid photodynamic therapy on microcomedones and macrocomedones

Background: Photodynamic therapy (PDT) with aminolevulinic acid (ALA) has been shown to be an effective treatment for acne. However, the effect of ALA PDT on comedo formation has never been objectively evaluated. Cyanoacrylate follicular biopsy (CFB), a noninvasive procedure, has been proposed as the most reliable tool for studying follicular casts. Objective: To determine the possible effect of ALA and red light (550-700 nm) on macro- and microcomedones in acne patients. Patients and Methods: 10 patients with mild-to-moderate facial and/or chest/back acne resistant to conventional therapies received ALA PDT at 2-week intervals in 3 sessions. The severity of acne had been estimated by a system of points, the Global Acne Grading System. The patients underwent PDT utilizing ALA 10% (face) or 15% (back/chest) and red light (15 J/cm2 each session). CFBs were performed. Results: Four weeks after their last PDT session, the patients showed an average global score reduction of 50%. CFBs demonstrated a reduction in the total area, the average area and the density of macrocomedones. Conclusion: The results obtained in this study using CFB evaluation demonstrate that ALA PDT exerts an action on the comedogenic phase as well

Langerhans' cell histiocytosis of the vulva: The use of photodynamic therapy

Background: The evaluation of possible efficacy of Photodynamic Therapy (PDT) in a rare condition of vulvar Langerhans' cell histiocytosis (LCH), in a 43-years-old women with one year history of pruritic vulvar lesions. Main observations: After a cycle of 5 sessions of PDT, with aminolevulinic acid (ALA) in low percentage (5%), the patient reported an improvement of lesions, and an high improvement of local symptoms, with a significant reduction of itch and pain. Conclusions: Our case confirms this single experience of literature for the treatment of vulvar LCH by PDT, with an improvement of disease's symptoms, and can suggest the use of PDT for this rare and untreated disease

Percutaneous collagen induction: An effective and safe treatment for post-acne scarring in different skin phototypes

Background: Atrophic scars can complicate moderate and severe acne. There are, at present, several modalities of treatment with different results. Percutaneous collagen induction (PCI) has recently been proposed as a simple and effective therapeutic option for the management of atrophic scars. Objective:The aim of our study was to analyze the efficacy and safety of percutaneous collagen induction for the treatment of acne scarring in different skin phototypes. Methods & materials: A total of 60 patients of skin types phototype I to VI were included in the study. They were divided into three groups before beginning treatment: Group A (phototypes I to II), Group B (phototypes III to V), and Group C (phototypes VI). Each patient had three treatments at monthly intervals. The aesthetic improvement was evaluated by using a Global Aesthetic Improvement Scale (GAIS), and analyzed statistically by computerized image analysis of the patients' photographs. The differences in the GAIS scores in the different time-points of each group were found using the Wilcoxon's test for nonparametric-dependent continuous variables. Computerized image analysis of silicone replicas was used to quantify the irregularity of the surface micro-relief with Fast Fourier Transformation (FFT); average values of gray were obtained along the x- and y-axes. The calculated indexes were the integrals of areas arising from the distribution of pixels along the axes. Results:All patients completed the study. The Wilcoxon's test for nonparametric-dependent continuous variables showed a statistically significant (p < 0.05) reduction in severity grade of acne scars at T5 compared to baseline (T1). The analysis of the surface micro-relief performed on skin replicas showed a decrease in the degree of irregularity of skin texture in all three groups of patients, with an average reduction of 31% in both axes after three sessions. No short- or long-term dyschromia was observed. Conclusion: PCI offers a simple and safe modality to improve the appearance of acne scars without risk of dyspigmentation in patient of all skin types. © 2014 Informa Healthcare USA on behalf of Informa UK Ltd