1,333 research outputs found
Análise do N-terminal da proteÃna capsidial de SCMV infectando milho e sorgo no Brasil.
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Pré-melhoramento de milho quanto à resistência a enfezamentos.
O objetivo deste trabalho foi selecionar famÃlias de milho derivadas do retrocruzamento entre o composto "NAP Corn Stunt" (genitor doador) e linhagens?elite (genitores recorrentes), quanto à produtividade de grãos e à resistência a enfezamentos, e avaliar a eficiência do emprego de marcadores moleculares para avaliação fenotÃpica na seleção de genótipos com alta produtividade de grãos. Foram avaliados 100 genótipos, em cinco condições ambientais, na safra agrÃcola 2009/2010. Foram selecionadas famÃlias RC1F2, que aliam a alta produtividade dos genitores recorrentes à resistência aos enfezamentos, presente no genitor doador. As famÃlias selecionadas quanto ao desempenho agronômico e à resistência aos enfezamentos foram: L228?3?324?S, L228?3?237?R, L228?3?109?R, que foram indicadas para cruzamentos com linhagens do grupo heterótico duro; e L3?422?R e L3?586?R, que foram indicadas para cruzamentos com linhagens do grupo heterótico dentado. Na seleção de genótipos de alta produtividade de grãos, a seleção assistida por marcadores moleculares não é eficiente para a recuperação do genótipo do pai recorrente, em comparação à avaliação fenotÃpica
Possible human-to-dog transmission of SARS-CoV-2, Italy, 2020
We detected severe acute respiratory syndrome coronavirus 2 in an otherwise healthy poodle living with 4 family members who had coronavirus disease. We observed antibodies in serum samples taken from the dog, indicating seroconversion. Full-length genome sequencing showed that the canine and human viruses were identical, suggesting human-to-animal transmission
Hypoglycemia Assessed by Continuous Glucose Monitoring Is Associated with Preclinical Atherosclerosis in Individuals with Impaired Glucose Tolerance
Hypoglycemia is associated with increased risk of cardiovascular adverse clinical outcomes. There is evidence that impaired glucose tolerance (IGT) is associated with cardiovascular morbidity and mortality. Whether IGT individuals have asymptomatic hypoglycemia under real-life conditions that are related to early atherosclerosis is unknown. To this aim, we measured episodes of hypoglycemia during continuous interstitial glucose monitoring (CGM) and evaluated their relationship with early manifestation of vascular atherosclerosis in glucose tolerant and intolerant individuals. An oral glucose tolerance test (OGTT) was performed in 79 non-diabetic subjects. Each individual underwent continuous glucose monitoring for 72 h. Cardiovascular risk factors and ultrasound measurement of carotid intima-media thickness (IMT) were evaluated. IGT individuals had a worse cardiovascular risk profile, including higher IMT, and spent significantly more time in hypoglycemia than glucose-tolerant individuals. IMT was significantly correlated with systolic (r = 0.22; P = 0.05) and diastolic blood pressure (r = 0.28; P = 0.01), total (r = 0.26; P = 0.02) and LDL cholesterol (r = 0.27; P = 0.01), 2-h glucose (r = 0.39; P<0.0001), insulin sensitivity (r = −0.26; P = 0.03), and minutes spent in hypoglycemia (r = 0.45; P<0.0001). In univariate analyses adjusted for gender, minutes spent in hypoglycemia were significantly correlated with age (r = 0.26; P = 0.01), waist circumference (r = 0.33; P = 0.003), 2-h glucose (r = 0.58; P<0.0001), and 2-h insulin (r = 0.27; P = 0.02). In a stepwise multivariate regression analysis, the variables significantly associated with IMT were minutes spent in hypoglycemia (r2 = 0.252; P<0.0001), and ISI index (r2 = 0.089; P = 0.004), accounting for 34.1% of the variation. Episodes of hypoglycemia may be considered as a new potential cardiovascular risk factor for IGT individuals
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