Patient-reported outcomes after lateral wall sinus floor elevation : a systematic review

Objectives: The aim of this systematic review is to assess patient-reported outcome measures (PROMs) after a sinus lift elevation by means of a lateral approach. Material and Methods: An electronic search was performed to search for eligible publications reporting PROMs after a lateral wall sinus lift procedure. Selected articles were further scrutinized and underwent a quality check before inclusion in a final study pool. Results: The electronic search provided us with 2444 articles of which 98 were further examined through a full-text analysis. Of these 98 studies, 11 were selected based on our inclusion and exclusion criteria. Results on a different number of PROMs were examined and compared: pain, edema, ability to eat, ability to work, phonetics, daily activities, bleeding, bruising, ability to sleep, bad breath, patient preference, and Oral Health Impact Profile-14 (OHIP-14). Methods of evaluation were 3-to 5-point scales, visual analog scale scores, and OHIP-14 questionnaires. Evaluation time points differed between 1 single evaluation time to a daily registration during 1 week. Conclusions: A general peak in discomfort could be noticed on day 1 postoperatively with a general decline thereafter. Severe morbidity or discomfort occurred but not in most patients

A 3-year prospective study on a porcine-derived acellular collagen matrix to re-establish convexity at the buccal aspect of single implants in the molar area : a volumetric analysis

Background: Xenogeneic soft tissue substitutes are currently being investigated as an alternative to subepithelial connective tissue grafts (CTG) with the intention to avoid postoperative morbidity associated with autologous grafting. The aim of the present study was to volumetrically evaluate the effectiveness and mid-long-term stability of a porcine-derived collagen matrix (PDCM) (Mucoderm (R), Botiss gmbh, Berlin, Germany) in increasing soft tissue volume at the buccal aspect of molar implant sites. Methods: Periodontally healthy non-smoking patients with a single tooth gap in the molar area were selected for a prospective case series. All sites had a bucco-oral bone dimension of at least 8 mm and demonstrated a horizontal alveolar defect. A wide diameter implant was placed under the elevated buccal flap and a PDCM was applied. The primary outcome was the linear increase in buccal soft tissue profile (BSP) within a well-defined area of interest. This was performed with designated software (SMOP; Swissmeda AG, Zurich, Switzerland) on the basis of superimposed digitalized study casts taken before surgery (T0), immediately after surgery (T1), at three months (T2), one year (T3) and three years (T4). Secondary outcomes were alveolar process deficiency and clinical parameters. Results: Fourteen out of 15 treated patients attended the three-year re-assessment (four females; mean age 51.4 years). Mean linear increase in BSP at T1 was 1.53 mm (p = 0.001). The PDCM showed substantial resorption at T2 (1.02 mm or 66.7%) (p = 0.001). Thereafter, a 0.66 mm volume gain was observed (p = 0.030), possibly due to the installation of a permanent crown displacing the soft tissues to the buccal aspect. This resulted in a linear increase in BSP of 1.17 mm (76.5%) at T4. Alveolar process deficiency significantly reduced over time (p = 0.004). However, 50% of patients still demonstrated a slight (6/14) or obvious (1/14) alveolar process deficiency at study termination. Implants demonstrated healthy clinical conditions. Conclusions: The PDCM demonstrated marked resorption during the early stages of healing. Due to the matrix thickening the tissues, and the permanent crown displacing the tissues, 76.5% of the initial increase in BSP could be maintained over a three-year period. Half of the patients failed to show perfect soft tissue convexity at the buccal aspect

A randomized controlled trial on the efficiency of free-handed, pilot-drill guided and fully guided implant surgery in partially edentulous patients

Objectives To compare the effectiveness of free-handed (FH), pilot-drill guided (PG) and fully guided (FG) implant surgery by means of the apical global deviation (AGD) in relation to the additional financial cost and time spent. Materials and methods Thirty-three partially edentulous patients in need of >= 2 implants in the posterior maxilla were randomly allocated to one of the following treatment groups: FH, PG and FG. Eleven patients (mean age 57; eight females; altogether 26 implants) were treated by FH surgery, 11 (mean age 53; seven females; altogether 24 implants) by PG surgery and 10 (mean age 60; six females; altogether 21 implants) by FG surgery. The accuracy in implant positioning was assessed by comparing the actual implant position to its planned position with the AGD as the main measure of effectiveness. Cost analysis included data on time investment (pre- and per-operative) and operational cost. The efficiency of PG and FG surgery was assessed by means of the incremental cost-effectiveness ratio (ICER), defined as the extra investment that is needed per unit reduction in AGD when compared to FH surgery. Results FG surgery was most effective (mean AGD: 0.97 mm) and FH surgery was least effective (mean AGD: 2.11 mm) in terms of surgical accuracy. As a result, 5/26 implants had to be restored with a cement-retained restoration following FH surgery, although screw-retention was planned for all implants in every group. The total time investment did not differ significantly between the 3 groups (p = 0.811). A significant additional cost per implant was found for PG and FG as compared to FH surgery pointing to 8.29% (euro176.54) and 10.45% (euro222.52), respectively (p < 0.001). The ICER revealed an additional cost of euro5.48 and euro4.12 per per cent reduction in AGD for PG and FG surgery, respectively. Conclusion The extra operational cost for guided implant surgery is acceptable and clinically justified since cementation can be avoided. FG surgery is the most efficient surgical approach, even though the absolute operational cost is higher when compared to PG and FH surgery

Long-term follow-up on root coverage with a double pedicle flap and connective tissue graft

Partial-thickness double pedicle flap and connective tissue graft (CTG) is a procedure to treat single gingival recession in the anterior mandible. However, long-term data have not been reported. Patients who had been treated by the same periodontist in a private practice in Belgium between 2002 and 2009 were invited to return for a clinical examination in 2017. Seventeen patients (15 females, 2 males; mean age: 34.6 years) with a total of 23 treated single recessions were reexamined after 8 to 15 years of follow-up. Between 1 and 8 to 15 years of follow-up, mean and complete root coverage did not differ and amounted to 75% and 44% at study termination, respectively (P =.204). The esthetic outcome was mediocre, given a final mean root coverage esthetic score of 6.52. The Mucosal Scarring Index demonstrated a significant reduction in scarring between 1 and 8 to 15 years of follow-up; however, 31% of the cases still demonstrated some scarring in the end. Patients were less critical than clinicians, as they expressed high esthetic (mean: 81) and low scarring (mean 14) scores on visual analog scales. Partial-thickness double pedicle flap and CTG is an effective root-coverage procedure. However, alternative techniques may need to be considered for esthetically demanding patients

Marginal and apical bone stability after staged sinus floor augmentation using bone condensing implants with variable-thread design : a two-dimensional analysis

Studies on the vertical stability of augmented bone after sinus lifting differ substantially. In addition, long healing periods are usually advocated prior to implant installation. The purpose of this case series study was to evaluate the changes in bone height after sinus lifting with a bovine-derived xenograft and to evaluate the clinical outcome of bone condensing implants installed after a short healing period. Patients treated during the years 2010-2013 were re-examined using peri-apical radiographs to evaluate the changes in augmented bone height (BH) and marginal bone loss (BL). Fifty-seven of 70 eligible subjects (28 male and 29 female, mean age 56 years) attended for reassessment. Data were available for 53 sinus lifts and 105 implants installed after a mean healing period of 4.6 +/- 1.5 months. Implant survival was 99% after a mean time in function of 19 9 months. Baseline BH, BH at implant placement, and final BH were on average 3.87 +/- 1.74 mm, 13.75 +/- 2.12 mm, and 13.11 +/- 2.12 mm, respectively (P < 0.001). Mean BL was 0.51 +/- 0.65 mm. Only limited resorption is to be expected after sinus lifting in the short term. A bone condensing implant can be used in the early healing phase with successful outcomes in terms of implant survival and bone adaptation

A randomized controlled trial comparing guided bone regeneration to connective tissue graft to re‐establish buccal convexity at dental implant sites : three‐year results

Objectives To compare guided bone regeneration (GBR) to connective tissue graft (CTG) in terms of increase in buccal soft tissue profile (BSP) at three-year follow-up when applied at the buccal aspect of single implant sites demonstrating a minor horizontal alveolar defect. Materials and methods Patients with a single tooth gap in the anterior maxilla and horizontal alveolar defect were enrolled in a single-blind RCT. All sites had a bucco-palatal bone dimension of at least 6 mm, received a single implant at least 3 months after tooth removal and were randomly allocated to the control (GBR) or test group (CTG) to re-establish buccal soft tissue convexity. Primary outcome was linear increase in BSP, meaning increase at the buccal aspect of the implant, based on superimposed digital surface models. Secondary outcomes were buccal bone and buccal soft tissue thickness, aesthetic and clinical parameters. Results Twenty-one patients were included per group at baseline. After three years, three patients in the GBR group and four in the CTG group were not willing to return for re-assessment. Hence, the final sample included 9 females/9 males (mean age 52) in the GBR group and 8 females / 9 males in the CTG group (mean age 49). The changes in BSP over time were not significantly different between GBR and CTG (p = 0.629). At three years, sites treated with GBR demonstrated 1.06 mm (95% CI: 0.83; 1.28) increase in BSP, whereas sites treated with CTG showed 0.99 mm (95% CI: 0.65; 1.35) increase in BSP (p = 0.699) compared to baseline. There were no significant differences between the groups for any of the parameters except for Mucosal Scarring Index, which was 1.63 (95% CI: 0.73; 2.53) lower for CTG (p = 0.002) at study termination. Conclusion There was no significant difference in linear increase in BSP between GBR and CTG after three years. Hence, clinical decision-making should be based on other factors

A one-year prospective study on alveolar ridge preservation using collagen-enriched deproteinized bovine bone mineral and saddle connective tissue graft : a cone beam computed tomography analysis

Background Although there is ample research on alveolar ridge preservation (ARP), changes of the soft tissue profile are seldom reported. In addition, the use of a saddle connective tissue graft (S-CTG) has only been described in one study. Purpose To evaluate changes in bone and external soft tissue profile following ARP of intact and nonintact sockets using collagen-enriched deproteinized bovine bone mineral (C-DBBM) and a S-CTG (a); to assess the need for additional hard and soft tissue grafting after ARP (b). Materials and Methods Patients in need of a single or multiple unit fixed reconstruction in the premaxilla were included in this prospective case series. After tooth extraction, sockets were grafted with C-DBBM and sealed with a S-CTG. Cone beam computed tomography slides taken before tooth extraction and 4 to 6 months after ARP were superimposed to measure changes in bone dimensions and external soft tissue profile. The need for additional hard and soft tissue grafting was registered. Implants were evaluated at 1 year. Patient-reported outcomes were registered on a 100 mm visual analogue scale at suture removal and 1 year following ARP. Results Nineteen teeth (10 with intact sockets, 9 with nonintact sockets) in 14 patients (11 females; mean age 34) were extracted and treated with the abovementioned protocol. Volume loss could not be prevented and mainly occurred at the buccal aspect. Maximum horizontal bone resorption was 1.27 mm and maximum horizontal shrinkage of the soft tissue profile amounted to 0.87 mm, both at the most cervical aspect. Additional GBR was necessary in two sites with a nonintact buccal bone wall. The need for additional soft tissue grafting was moderate in sites with intact (3/10) and high in nonintact sockets (6/9). Implants demonstrated favorable clinical and esthetic outcomes. Pain intensity and patient satisfaction were 17 and 94, respectively. Conclusion Alveolar ridge preservation was not able to prevent relevant tissue changes. However, implants could be installed as planned. Although the application of a S-CTG partly compensated for the buccal bone loss, the need for additional soft tissue grafting was still moderate in intact sockets and high in nonintact sockets

A randomized controlled study on the accuracy of free-handed, pilot-drill guided and fully guided implant surgery in partially edentulous patients

Aim: To compare the accuracy of free-handed (FH), pilot-drill guided (PG) and fully guided (FG) implant surgery. Materials and methods: Partially edentulous patients in need of 2 implants in the posterior maxilla were randomly allocated to one of the following treatment groups: FH, PG and FG. Ideal implant positions were determined in designated software following the fusion of bony information (CBCT data in DICOM format) to the prosthetic wax-up (optical scan data in STL format). The position of every implant as surgically realized was compared to its ideal position. The apical global deviation (AGD) was the primary outcome of the study. Secondary outcome variables were angular deviation (AD), coronal global deviation (CGD), coronal lateral deviation (CLD), coronal vertical deviation (CVD), apical lateral deviation (ALD) and apical vertical deviation (AVD). Results: Eleven patients (mean age 57; three males; eight females; altogether 26 implants) were treated by FH surgery, 11 (mean age 53; four males; seven females; altogether 24 implants) by PG surgery and 10 (mean age 60; four males; six females; altogether 21 implants) by FG surgery. FG surgery was most accurate (mean AGD: 0.97mm; maximum AGD: 1.98mm) followed by PG surgery (mean AGD: 1.43mm; maximum AGD: 2.72mm). FH surgery resulted in huge deviation from the ideal position (mean AGD: 2.11mm; maximum AGD: 4.84mm). The results on most secondary outcome variables followed the same order. Although screw-retained restorations were planned for all implants, five of 26 in the FH group and one of 24 in the PG group had to be restored by means of a cement-retained restoration. Conclusion: When perfect implant positioning is required, FG surgery should be considered the gold standard approach

A multicenter cohort study on the association of the one‐abutment one‐time concept with marginal bone loss around bone level implants

Objectives To investigate the association of the one-abutment one-time concept with marginal bone loss (MBL) around bone-level implants in relation to other factors. Materials and methods Records from patients treated by four experienced implant surgeons between January 2016 and July 2019 were scrutinized. Subjects treated with two bone-level implant types with varying machined collar (subgroups: 0.5 and 0.8 mm) were considered, receiving a healing abutment (HA cohort) or a permanent abutment at the time of surgery (OT cohort). The primary outcome was MBL registered at 3 months and the longest follow-up. A clustered two-part regression model for semicontinuous data was used. Results Data pertaining to 160 patients (92 females, mean age 54) and 344 implants (125 in HA cohort, 219 in OT cohort) were available for evaluation. Mean MBL amounted to 0.52 mm (SD 0.68) after a mean follow-up of 20 (SD 9.2) months, with 33.8% of the implants showing complete bone preservation and 5.0% demonstrating >2mm MBL. OT was not related to the presence of MBL using MBL as dependent binary variable (0: no MBL; 1: MBL irrespective of its magnitude). However, OT significantly reduced the magnitude of MBL with 0.300mm when compared to HA (p = .023) in the cases where MBL was detected. Subgroup (p = .212), smoking (p = .789), history of periodontitis (p = .839), type of edentulism (p = .054), implant surgeon (p = .079), patient compliance (p = .617), and follow-up (p = .443) failed to show a significant association with MBL in the regression model. Ninety-eight % of the implants survived. Conclusion Within the limitations of a cohort study, the one-abutment one-time concept was associated with a decrease in MBL at implant sites with bone loss. Therefore, the placement of a permanent abutment at the time of surgery seems relevant to limit marginal bone-level alterations