Càlcul distribuït en BOINC per el trencament de l'algorisme RC5

Aquest projecte té com a objectiu participar en el desafiament d'RSA Laboratories corresponent a trencar el criptosistema RC5-32-12-9 proposat. Per realitzar-ho s'ha triat realitzar un atac per força bruta, mitjançant el càlcul distribuït i, més concretament, utilitzant la Public Resource Computing. La plataforma escollida és la Berkeley Open Infrastructure for Network Computing (BOINC), coneguda per la seva utilització en grans projectes com ara SETI@home. En aquest projecte es posa en funcionament la infraestructura i es desenvolupen les aplicacions necessàries per iniciar els càlculs que haurien de permetre el trencament del criptosistema.Este proyecto tiene como objetivo participar en el desafío de RSA Laboratories correspondiente a romper el criptosistema RC5-32-12-9 propuesto. Para realizarlo se ha escogido realizar un ataque por fuerza bruta, usando el càlculo distribuido y, más concretamente, la Public Resource Computing. La plataforma escogida es la Berkeley Open Infrastructure for Network Computing (BOINC), conocida por ser usada en grandes proyectos como SETI@home. El este proyecto se pone en funcionamiento la infraestructura y se desarrollan las aplicaciones necesarias para iniciar los cálculos que deberían permitir romper el criptosistema.The main objective of this project is to participate in the challenge of RSA Laboratories corresponding to break the cryptosystem RC5-32-12-9. The strategy used to achieve this goal is to use a brute force attack using distributed computing techniques and, more precisely, Public Resource Computing. The chosen platform is the Berkeley Open Infrastructure for Network Computing (BOINC), a well known infrastructure since it has been used in large projects like SETI@home. In this project the BOINC infrastructure has been configured and it has been developed all necessary applications n order to start the computation that should allow breaking the proposed cryptosystem.Nota: Aquest document conté originàriament altre material i/o programari només consultable a la Biblioteca de Ciència i Tecnologia

Surgeon-led 7-INCut Antibiotic Stewardship Intervention Decreases Duration of Treatment and Carbapenem Use in a General Surgery Service

Agents antibacterians; Ús terapèutic; Administració d'antimicrobians; Cirurgia general; EstàndardsAgentes antibacterianos; Uso terapéutico; Administración de antimicrobianos; Cirugía general; NormasAnti-bacterial agents; Therapeutic use; Antimicrobial stewardship; General surgery; StandardsAntibiotic stewardship programs optimize the use of antimicrobials to prevent the development of resistance and improve patient outcomes. In this prospective interventional study, a multidisciplinary team led by surgeons implemented a program aimed at shortening the duration of antibiotic treatment <7 days. The impact of the intervention on antibiotic consumption adjusted to bed-days and discharges, and the isolation of multiresistant bacteria (MRB) was also studied. Furthermore, the surgeons were surveyed regarding their beliefs and feelings about the program. Out of 1409 patients, 40.7% received antibiotic therapy. Treatment continued for over 7 days in 21.5% of cases, and, as can be expected, source control was achieved in only 48.8% of these cases. The recommendations were followed in 90.2% of cases, the most frequent being to withdraw the treatment (55.6%). During the first 16 months of the intervention, a sharp decrease in the percentage of extended treatments, with R2 = 0.111 was observed. The program was very well accepted by surgeons, and achieved a decrease in both the consumption of carbapenems and in the number of MRB isolations. Multidisciplinary stewardship teams led by surgeons seem to be well received and able to better manage antibiotic prescription in surgery