Number of regulated probe-sets in the endometrial biopsies.

<p>The numbers at the horizontal arrows indicate the quantity of probe-sets significantly regulated between the adjacent stages within either the HR or the LR group, whereas the numbers in the intersections indicate the quantity of probe-sets commonly regulated between day 3 to day 7 (↑ = higher transcript abundance at day 3, ↓ = lower transcript abundance at day 3) in both the HR and the LR group. The numbers at vertical arrows are the number of probe-sets differentially expressed between HR and LR at the same day of estrous cycle (↑ = higher transcript abundance in the HR groups, ↓ = lower transcript abundance in the HR groups).</p

Transcription factors associated with the differential transcript abundance among the experimental groups.

1<p>z-score indications significance of prediction of activation status of the respective transcription factor; it is predicted to be activated at z-score ≥2 or inhibited at z-score ≤−2:</p>2<p>overlap p-value: indicates significance of the association between the respective transcription factor and the predicated target genes showing differential expression in the experiment; threshold p≤5.0E-02.</p

Comparison of microarray data and qRT-PCR of selected transcripts.

<p>Comparison of microarray data and qRT-PCR of selected transcripts.</p

Canonical pathways enriched for transcripts showing different abundance depending on receptivity group and day of estrous cycle.

<p>Pathways showing temporal regulation from day 3 to day 7 are given at the horizontal vectors of either the HR (top part) or the LR group (lower part) (↑ = higher transcript abundance at day 3, ↓ = lower transcript abundance at day 3). Pathways of transcript showing different abundance among the Hr and LR at day 3 (left) or day 7 od estrous cycle are displayed at the vertical vectors (↑ = higher transcript abundance in the HR groups, ↓ = lower transcript abundance in the HR groups).</p

Molecular and cellular functions of transcripts with different abundance in the HR and LR groups at day 3 of the estrous cycle.

<p>Molecular and cellular functions of transcripts with different abundance in the HR and LR groups at day 3 of the estrous cycle.</p

Target genes of TP53 as predicted by IPA.

<p>Target genes of TP53 as predicted by IPA.</p

Molecular and cellular functions of transcripts with different changes of abundance between day 3 and day 7 of the estrous cycle in the HR groups.

<p>Molecular and cellular functions of transcripts with different changes of abundance between day 3 and day 7 of the estrous cycle in the HR groups.</p

Molecular and cellular functions of transcripts with different abundance in the HR and LR groups at day 7 of the estrous cycle.

<p>Molecular and cellular functions of transcripts with different abundance in the HR and LR groups at day 7 of the estrous cycle.</p

Additional file 1: of MicroRNA-424/503 cluster members regulate bovine granulosa cell proliferation and cell cycle progression by targeting SMAD7 gene through activin signalling pathway

Table S1. Sequence specific primers used for pmirGLO and 3´-UTR amplification of the SMAD7 and ACVR2A gene harboring binding site for miR-424-5p and miR-503-5p. Table S2. Sequence specific primers used for analysis of the relative expression of genes. (PDF 83 kb

Additional file 1: of MicroRNA-424/503 cluster members regulate bovine granulosa cell proliferation and cell cycle progression by targeting SMAD7 gene through activin signalling pathway

Table S1. Sequence specific primers used for pmirGLO and 3´-UTR amplification of the SMAD7 and ACVR2A gene harboring binding site for miR-424-5p and miR-503-5p. Table S2. Sequence specific primers used for analysis of the relative expression of genes. (PDF 83 kb