Nonhalogenated organic molecules from Laurencia algae

The marine red algae of the genus Laurencia have produced more 700 secondary metabolites and exhibited high molecular diversity and intriguing bioactivity. Since the halogenated structures have been comprehensively reviewed previously, this review, covering up to the end of 2012, mainly focuses on the source, structure elucidation, and bioactivity of nonhalogenated organic molecules from Laurencia spp. as well as the relationship between nonhalogenated and halogenated products. Overall, 173 new or new naturally occurring compounds with 58 skeletons, mainly including sesquiterpenes, diterpenes, triterpenes, and C15-acetogenins, are described.The marine red algae of the genus Laurencia have produced more 700 secondary metabolites and exhibited high molecular diversity and intriguing bioactivity. Since the halogenated structures have been comprehensively reviewed previously, this review, covering up to the end of 2012, mainly focuses on the source, structure elucidation, and bioactivity of nonhalogenated organic molecules from Laurencia spp. as well as the relationship between nonhalogenated and halogenated products. Overall, 173 new or new naturally occurring compounds with 58 skeletons, mainly including sesquiterpenes, diterpenes, triterpenes, and C-15-acetogenins, are described

Giovanni Battista Marini Bettolo: su incidencia en el desarrollo de la química en Uruguay Giovanni Battista Marini Bettolo: his role in the development of chemistry in Uruguay

Uruguay es un pequeño país sudamericano en el cual la enseñanza de la química está centralizada, desde 1929, en la Facultad de Química de la Universidad de la República. Una tradición centrada en la enseñanza de la comunidad académica de esta Facultad comenzó a virar hacia una fuerte importancia de la tarea investigativa en forma coincidente con la llegada del profesor Giovanni Marini Bettolo al país en 1948. En este trabajo se estudia la incidencia del profesor y de los investigadores entrenados por él y sus sucesores. Constituye una aproximación preliminar al estudio de la relevancia cuantitativa y cualitativa de este conjunto de docentes en la producción global de la investigación en química del país, a modo de avance o primer paso que siente las bases de investigaciones futuras sobre la química uruguaya.<br>Uruguay is a small South American country where the teaching of chemistry has been centralized at the Universidad de la República's School of Chemistry since 1929. Traditionally centered on teaching the academic community at this institution, the School began moving towards a heavier emphasis on research when Professor Giovanni Marini Bettolo arrived in Uruguay in 1948. The article examines Bettolo's role and the role of the researchers trained by him and his successors. This is a preliminary approach to the study of the quantitative and qualitative impact that this set of teachers had within overall research production in chemistry in Uruguay; it is meant as a first step that lays a foundation for future studies of the topic