Evidence for Investigating GSK-3 Inhibitors as Potential Therapeutics for Severe COVID-19

We revealed that SARS-CoV-2 spike protein induces CXCL10 and GSK-3 inhibitors are potential therapeutics for severe COVID-19

Attenuation of SARS-CoV-2-induced Cytokine Expression by GSK-3 Inhibitors

Components of the spike protein of SARS-CoV-2 appear to induce cytokine expression which is attenuated by GSK-3 inhibitors

Effect of precede model-based education on quality of life in patients with type 2 diabetes

The increasing prevalence rate has made diabetes a world epidemic. Considering diabetes complications and associated effects on patients’ quality of life, this interventional study was performed to promote the life quality using education based on the Precede model in the rural areas of Andimeshk. This experimental study was conducted on 120 patients with type II diabetes who were randomly allocated to the experimental and control groups. The data were collected using two questionnaires including the Precede model framework and Short Form health survey (SF-36). The precede model-based intervention composed of six educational sessions (60 to 90 minutes a session). The patients were followed up for three months post-intervention and examined for glycated hemoglobin (Hemoglobin A1c or HbAlc). After educational intervention, the mean score of quality of life had a significant increase in the experimental group compared with the control group.The mean scores of Precede model constructs inpatients of the experimental group increased significantly after the intervention compared with the before intervention. Moreover, the mean score of HbA1c improved significantly in the experimental group compared to the control group. The present study indicated that the educational intervention program based on the Precede model has a positive effect on quality of life among diabetic patients