An Analysis of Air Mobility Express Requirements Operating Within a Lean Logistics Wartime Environment

Lean Logistics was developed in response to budget cuts, force reductions, and a new political world order. The primary objective of Lean Logistics is to minimize the total system wide costs of the Air Force organization. Currently, the Air Force is seeking to cut costs by reducing inventories, improving repair processes, and employing faster transportation where possible. The purpose of this thesis is to determine if the Air Mobility Express (AMX) current sizing plan is capable of supporting the retrograde assets generated during the sustainment portion of a war. The Dyna-METRIC version 6.4 simulation program is employed to analyze the effect of varying such parameters as flying hours and retrograde shipment time on the weight and space required to move retrograde assets. Analysis of the results was accomplished using a Small Sample Test of Hypothesis. The results indicated that the current sizing plan is capable of handling the retrograde cargo generated by four F-16C squadrons for the six scenarios evaluated. This research also hints that while the current plan is capable of supporting four F-16C squadrons, it should be increased to support the transportation of reparables for all weapon systems involved in the war effort

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead