21,168 research outputs found

    On rigidly rotating perfect fluid cylinders

    Full text link
    The gravitational field of a rigidly rotating perfect fluid cylinder with gamma- law equation of state is found analytically. The solution has two parameters and is physically realistic for gamma in the interval (1.41,2]. Closed timelike curves always appear at large distances.Comment: 10 pages, Revtex (galley

    Feasibility model of a high reliability five-year tape transport. Volume 3: Appendices

    Get PDF
    Detailed drawings of the five year tape transport are presented. Analytical tools used in the various analyses are described. These analyses include: tape guidance, tape stress over crowned rollers, tape pack stress program, response (computer) program, and control system electronics description

    Precise Determination of Electroweak Parameters in Neutrino-Nucleon Scattering

    Full text link
    A systematic error in the extraction of sin2θW\sin^2 \theta_W from nuclear deep inelastic scattering of neutrinos and antineutrinos arises from higher-twist effects arising from nuclear shadowing. We explain that these effects cause a correction to the results of the recently reported significant deviation from the Standard Model that is potentially as large as the deviation claimed, and of a sign that cannot be determined without an extremely careful study of the data set used to model the input parton distribution functions.Comment: 3pages, 0 figures, version to be published by IJMP

    Advanced components for spaceborne infrared astronomy

    Get PDF
    The need for improved cryogenic components to be used in future spaceborne infrared astronomy missions was identified. Improved low noise cryogenic amplifiers operated with infrared detectors, and better cryogenic actuators and motors with extremely low power dissipation are needed. The feasibility of achieving technological breakthroughs in both of these areas was studied. An improved silicon junction field effect transistor (JFET) could be developed if: (1) high purity silicon; (2) optimum dopants; and (3) very high doping levels are used. The feasibility of a simple stepper motor equipped with superconducting coils is demonstrated by construction of such a device based on a standard commercial motor. It is found that useful levels of torque at immeasurably low power levels were achieved. It is concluded that with modest development and optimization efforts, significant performance gains is possible for both cryogenic preamplifiers and superconducting motors and actuators

    Regions of beta 2 and beta 4 responsible for differences between the steady state dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors

    Get PDF
    We constructed chimeras of the rat beta 2 and beta 4 neuronal nicotinic subunits to locate the regions that contribute to differences between the acetylcholine (ACh) dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 receptors. Expressed in Xenopus oocytes, the alpha 3 beta 2 receptor displays an EC50 for ACh approximately 20-fold less than the EC50 of the alpha 3 beta 4 receptor. The apparent Hill slope (n(app)) of alpha 3 beta 2 is near one whereas the alpha 3 beta 4 receptor displays an n(app) near two. Substitutions within the first 120 residues convert the EC50 for ACh from one wild-type value to the other. Exchanging just beta 2:104-120 for the corresponding region of beta 4 shifts the EC50 of ACh dose-response relationship in the expected direction but does not completely convert the EC50 of the dose- response relationship from one wild-type value to the other. However, substitutions in the beta 2:104-120 region do account for the relative sensitivity of the alpha 3 beta 2 receptor to cytisine, tetramethylammonium, and ACh. The expression of beta 4-like (strong) cooperativity requires an extensive region of beta 4 (beta 4:1-301). Relatively short beta 2 substitutions (beta 2:104-120) can reduce cooperativity to beta 2-like values. The results suggest that amino acids within the first 120 residues of beta 2 and the corresponding region of beta 4 contribute to an agonist binding site that bridges the alpha and beta subunits in neuronal nicotinic receptors

    Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter

    Get PDF
    We report that activators and inhibitors of protein kinase C (PKC) and protein phosphatases regulate the activity of a cloned rat brain gamma- aminobutyric acid (GABA) transporter (GAT1) expressed in Xenopus oocytes. Four compounds known to activate PKC increased GABA uptake 2- 3.5-fold over basal control levels. Inhibition of PKC by bisindolylmaleimide reduced basal GABA uptake 80% and blocked the phorbol 12-myristate 13-acetate (PMA)-induced stimulation of transport. Okadaic acid, a protein phosphatase inhibitor, stimulated transport 2.5- fold; a 4-fold increase in GABA uptake occurred when oocytes were treated with cyclosporin A, a specific inhibitor of protein phosphatase 2B. Modulation resulted in changes to Vmax but not to Km and was influenced by the functional expression level of the transporter protein; as expression level increased, the ability to up-regulate transporter activity decreased. Down-regulation of transporter activity was independent of expression level. Modulation did not occur through phosphorylation of the three consensus PKC sites predicted by the primary protein sequence since their removal had no effect on the susceptibility of the transporter to modulation by PMA or bisindolylmaleimide. Subcellular fractionation of oocyte membranes demonstrated that under basal level conditions, the majority of GAT1 was targeted to a cytoplasmic compartment corresponding to the trans- Golgi or low density vesicles. Stimulation of PKC with PMA resulted in a translocation of transporters from this compartment to the plasma membrane. At higher expression levels of GAT1 protein, a larger portion of GAT1 was found on the plasma membrane during basal level conditions and treatment with bisindolylmaleimide resulted in removal of these transporters from the plasma membrane. At expression levels demonstrated to be resistant to modulation by PMA, PMA-treatment still resulted in translocation of transporters from the cytoplasm to the plasma membrane. Thus, the inability of PMA to increase uptake at high expression of the GAT1 protein is due to saturation at a step subsequent to translocation. These findings 1) demonstrate the presence of a novel regulated secretory pathway in oocytes and 2) suggest a modulatory mechanism for neurotransmitter transporters that could have significant effects upon synaptic function

    Accomplishments of the NASA Johnson Space Center portion of the soil moisture project in fiscal year 1981

    Get PDF
    The NASA/JSC ground scatterometer system was used in a row structure and row direction effects experiment to understand these effects on radar remote sensing of soil moisture. Also, a modification of the scatterometer system was begun and is continuing, to allow cross-polarization experiments to be conducted in fiscal years 1982 and 1983. Preprocessing of the 1978 agricultural soil moisture experiment (ASME) data was completed. Preparations for analysis of the ASME data is fiscal year 1982 were completed. A radar image simulation procedure developed by the University of Kansas is being improved. Profile soil moisture model outputs were compared quantitatively for the same soil and climate conditions. A new model was developed and tested to predict the soil moisture characteristic (water tension versus volumetric soil moisture content) from particle-size distribution and bulk density data. Relationships between surface-zone soil moisture, surface flux, and subsurface moisture conditions are being studied as well as the ways in which measured soil moisture (as obtained from remote sensing) can be used for agricultural applications

    A predictive formulation of the Nambu--Jona-Lasinio model

    Full text link
    A novel strategy to handle divergences typical of perturbative calculations is implemented for the Nambu--Jona-Lasinio model and its phenomenological consequences investigated. The central idea of the method is to avoid the critical step involved in the regularization process, namely the explicit evaluation of divergent integrals. This goal is achieved by assuming a regularization distribution in an implicit way and making use, in intermediary steps, only of very general properties of such regularization. The finite parts are separated of the divergent ones and integrated free from effects of the regularization. The divergent parts are organized in terms of standard objects which are independent of the (arbitrary) momenta running in internal lines of loop graphs. Through the analysis of symmetry relations, a set of properties for the divergent objects are identified, which we denominate consistency relations, reducing the number of divergent objects to only a few ones. The calculational strategy eliminates unphysical dependencies of the arbitrary choices for the routing of internal momenta, leading to ambiguity-free, and symmetry-preserving physical amplitudes. We show that the imposition of scale properties for the basic divergent objects leads to a critical condition for the constituent quark mass such that the remaining arbitrariness is removed. The model become predictive in the sense that its phenomenological consequences do not depend on possible choices made in intermediary steps. Numerical results are obtained for physical quantities at the one-loop level for the pion and sigma masses and pion-quark and sigma-quark coupling constants.Comment: 38 pages, 1 figure, To appear in Phy.Rev.

    Precision measurement of light shifts at two off-resonant wavelengths in a single trapped Ba+ ion and determination of atomic dipole matrix elements

    Full text link
    We define and measure the ratio (R) of the vector ac-Stark effect (or light shift) in the 6S_1/2 and 5D_3/2 states of a single trapped barium ion to 0.2% accuracy at two different off-resonant wavelengths. We earlier found R = -11.494(13) at 514.531nm and now report the value at 1111.68nm, R = +0.4176(8). These observations together yield a value of the matrix element, previously unknown in the literature. Also, comparison of our results with an ab initio calculation of dynamic polarizability would yield a new test of atomic theory and improve the understanding of atomic structure needed to interpret a proposed atomic parity violation experiment.Comment: 12 pages, 11 figures, in submission to PR
    corecore