The gravity dual of supersymmetric gauge theories on a squashed S1×S3S^1 \times S^3

We present a new one-parameter family of supersymmetric solutions deforming AdS_5. This is constructed as an asymptotically locally anti de Sitter (AlAdS) solution of five-dimensional minimal gauged supergravity, with topology R x R^4 and a non-trivial graviphoton field, and can be uplifted to ten or eleven dimensional supergravities. An analytic continuation of this solution yields the gravity dual to a class of four-dimensional N=1 supersymmetric gauge theories on a curved manifold with topology S^1 x S^3, comprising an SU(2) x U(1)-symmetric squashed three-sphere, with a non-trivial background gauge field coupling to the R-symmetry current. We compute the holographically renormalised on-shell action and interpret it in terms of the Casimir energy of the dual field theory. We also determine the holographic conserved charges of the solution and discuss relations between them.Comment: 57 pages, 5 figures. v4: version published in JHE

Localization on Hopf surfaces

We discuss localization of the path integral for supersymmetric gauge theories with an R-symmetry on Hermitian four-manifolds. After presenting the localization locus equations for the general case, we focus on backgrounds with S^1 x S^3 topology, admitting two supercharges of opposite R-charge. These are Hopf surfaces, with two complex structure moduli p,q. We compute the localized partition function on such Hopf surfaces, allowing for a very large class of Hermitian metrics, and prove that this is proportional to the supersymmetric index with fugacities p,q. Using zeta function regularisation, we determine the exact proportionality factor, finding that it depends only on p,q, and on the anomaly coefficients a, c of the field theory. This may be interpreted as a supersymmetric Casimir energy, and provides the leading order contribution to the partition function in a large N expansion.Comment: v2: discussion of background reality conditions modified and other minor changes, references added; v3: further minor corrections, version accepted for publication in JHE

Microscopic origin of the Bekenstein-Hawking entropy of supersymmetric AdS5_{\bf 5} black holes

We present a holographic derivation of the entropy of supersymmetric asymptotically AdS$_5$ black holes. We define a BPS limit of black hole thermodynamics by first focussing on a supersymmetric family of complexified solutions and then reaching extremality. We show that in this limit the black hole entropy is the Legendre transform of the on-shell gravitational action with respect to three chemical potentials subject to a constraint. This constraint follows from supersymmetry and regularity in the Euclidean bulk geometry. Further, we calculate, using localization, the exact partition function of the dual $\mathcal{N}=1$ SCFT on a twisted $S^1\times S^3$ with complexified chemical potentials obeying this constraint. This defines a generalization of the supersymmetric Casimir energy, whose Legendre transform at large $N$ exactly reproduces the Bekenstein-Hawking entropy of the black hole.Comment: v4: minor changes, version published in JHE

The large-NN limit of the 4d N=1\mathcal{N}=1 superconformal index

We systematically analyze the large-$N$ limit of the superconformal index of $\mathcal{N}=1$ superconformal theories having a quiver description. The index of these theories is known in terms of unitary matrix integrals, which we calculate using the recently-developed technique of elliptic extension. This technique allows us to easily evaluate the integral as a sum over saddle points of an effective action in the limit where the rank of the gauge group is infinite. For a generic quiver theory under consideration, we find a special family of saddles whose effective action takes a universal form controlled by the anomaly coefficients of the theory. This family includes the known supersymmetric black hole solution in the holographically dual AdS$_5$ theories. We then analyze the index refined by turning on flavor chemical potentials. We show that, for a certain range of chemical potentials, the effective action again takes a universal cubic form that is controlled by the anomaly coefficients of the theory. Finally, we present a large class of solutions to the saddle-point equations which are labelled by group homomorphisms of finite abelian groups of order $N$ into the torus.Comment: 58 pages; v2: minor changes, published versio

Leptin Increases: Physiological Roles in the Control of Sympathetic Nerve Activity, Energy Balance, and the Hypothalamic-Pituitary-Thyroid Axis

: It is well established that decreases in plasma leptin levels, as with fasting, signal starvation and elicit appropriate physiological responses, such as increasing the drive to eat and decreasing energy expenditure. These responses are mediated largely by suppression of the actions of leptin in the hypothalamus, most notably on arcuate nucleus (ArcN) orexigenic neuropeptide Y neurons and anorexic pro-opiomelanocortin neurons. However, the question addressed in this review is whether the effects of increased leptin levels are also significant on the long-term control of energy balance, despite conventional wisdom to the contrary. We focus on leptin's actions (in both lean and obese individuals) to decrease food intake, increase sympathetic nerve activity, and support the hypothalamic-pituitary-thyroid axis, with particular attention to sex differences. We also elaborate on obesity-induced inflammation and its role in the altered actions of leptin during obesity

The Casimir Energy in Curved Space and its Supersymmetric Counterpart

We study $d$-dimensional Conformal Field Theories (CFTs) on the cylinder, $S^{d-1}\times \mathbb{R}$, and its deformations. In $d=2$ the Casimir energy (i.e. the vacuum energy) is universal and is related to the central charge $c$. In $d=4$ the vacuum energy depends on the regularization scheme and has no intrinsic value. We show that this property extends to infinitesimally deformed cylinders and support this conclusion with a holographic check. However, for $\mathcal{N}=1$ supersymmetric CFTs, a natural analog of the Casimir energy turns out to be scheme independent and thus intrinsic. We give two proofs of this result. We compute the Casimir energy for such theories by reducing to a problem in supersymmetric quantum mechanics. For the round cylinder the vacuum energy is proportional to $a+3c$. We also compute the dependence of the Casimir energy on the squashing parameter of the cylinder. Finally, we revisit the problem of supersymmetric regularization of the path integral on Hopf surfaces.Comment: 53 pages; v2: minor changes, references added, version published in JHE

Supersymmetric counterterms from new minimal supergravity

We present a systematic classification of counterterms of four-dimensional supersymmetric field theories on curved space, obtained as the rigid limit of new minimal supergravity. These are supergravity invariants constructed using the field theory background fields. We demonstrate that if the background preserves two supercharges of opposite chirality, then all dimensionless counterterms vanish, implying that in this case the supersymmetric partition function is free of ambiguities. When only one Euclidean supercharge is preserved, we describe the ambiguities that appear in the partition function, in particular in the dependence on marginal couplings.Comment: 42 pages; v2: minor corrections, references adde

Comments on supersymmetric solutions of minimal gauged supergravity in five dimensions

We investigate supersymmetric solutions of minimal gauged supergravity in five dimensions, in the timelike class. We propose an ansatz based on a four-dimensional local orthotoric Kähler metric and reduce the problem to a single sixth-order equation for two functions, each of one variable. We find an analytic, asymptotically locally AdS solution comprising five parameters. For a conformally flat boundary, this reduces to a previously known solution with three parameters, representing the most general solution of this type known in the minimal theory. We discuss the possible relevance of certain topological solitons contained in the latter to account for the supersymmetric Casimir energy of dual superconformal field theories on ${S}^{3}\times {\mathbb{R}}$. Although we obtain a negative response, our analysis clarifies several aspects of these solutions. In particular, we show that there exists a unique regular topological soliton in this family