Esterification reactions.

<p>Esterification reactions.</p

Bioassay of magnolol 1 and honokiol 2.

<p>Effect of magnolol <b>1</b> and honokiol <b>2</b> on HepG2 cells (A and B) and HFF1 cells (C and D) at concentrations of 1–80 μM after 24 and 48 h, respectively. *** = <0.001, **** = <0.0001 <i>vs</i>. control.</p

Microwave preparation of biphenyls 5–7.

<p>Microwave preparation of biphenyls 5–7.</p

Revue de l'instruction publique en France et dans les pays étrangers

10 avril 18561856/04/10 (A16,N2)-1856/04/10

Bioassay of compound 12.

<p>Effect of honokiol monobutyrate <b>12</b> on HepG2 cells (A and B) and HFF1 cells (C and D) at concentrations of 1–80 μM after 24 and 48 h, respectively. ** = <0.01,*** = <0.001, **** = <0.0001 <i>vs</i>. control.</p

Esterification reactions.

<p>Esterification reactions.</p

Additional file 1: Table S1. of Protein expression changes induced in a malignant melanoma cell line by the curcumin analogue compound D6

Control MM cells identified proteins. Complete list of proteins identified from the untreated malignant melanoma cells (control). Normalized spectral abundance factor (NSAF) values are reported for each protein. (XLS 160 kb

Additional file 2: Table S2. of Protein expression changes induced in a malignant melanoma cell line by the curcumin analogue compound D6

D6 treated MM cells identified proteins. Complete list of proteins identified from the 10 ΟM D6 treated malignant melanoma cells (treated). Normalized spectral abundance factor (NSAF) values are reported for each protein. (XLS 142 kb

Natural and Natural-like Phenolic Inhibitors of Type B Trichothecene <i>in Vitro</i> Production by the Wheat (Triticum sp.) Pathogen Fusarium culmorum

Fusarium culmorum, a fungal pathogen of small grain cereals, produces 4-deoxynivalenol and its acetylated derivatives that may cause toxicoses on humans or animals consuming contaminated food or feed. Natural and natural-like compounds belonging to phenol and hydroxylated biphenyl structural classes were tested <i>in vitro</i> to determine their activity on vegetative growth and trichothecene biosynthesis by F. culmorum. Most of the compounds tested at 1.5 or 1.0 mM reduced 3-acetyl-4-deoxynivalenol production by over 70% compared to the control, without affecting fungal growth significantly. Furthermore, several compounds retained their ability to inhibit toxin <i>in vitro</i> production at the lowest concentrations of 0.5 and 0.25 mM. Magnolol <b>27</b> showed fungicidal activity even at 0.1 mM. No linear correlation was observed between antioxidant properties of the compounds and their ability to inhibit fungal growth and mycotoxigenic capacity. A guaiacyl unit in the structure may play a key role in trichothecene inhibition