541 research outputs found

    Hypermedia computer-based education in social work education

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    Journal ArticleHypermedia computer-based education (CBE) is an emerging information technology that makes possible user-directed, nonsequential exploration of, and interaction with, information presented through a variety of media including text, animation, graphics, sound, and video

    The Emergence of Commercial Scale Offshore Wind: Progress Made and Challenges Ahead

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    This Article examines the offshore wind development process from leasing and permitting to electric power supply and interconnection. Willing developers may divide the process into three discrete, but not necessarily sequential, endeavors. First, the developer must secure a viable purchaser or market for the output. “Offshore wind energy” is a more complex commercial product than one might envision—it includes the actual electric energy produced, the electric generating capacity that is available to serve load, and both the environmental and clean energy attributes of wind energy. The environmental and clean energy attributes may have an economic and regulatory value separate from, or in addition to, the value of the electric energy itself. These separate complexities give rise to several questions: What are the available markets for actual offshore wind energy? How does a developer find a buyer (off-taker) for the offshore wind electric output? How are the markets for the actual energy and the environmental attributes, normally embodied in a “renewable energy certificate” (REC), combined or otherwise related? How much control can individual states exercise over the decisions of an individual utility or other purchasers of offshore wind energy and RECs (or each of them separately)? If the average cost to the developer of electric energy generation from offshore wind per kilowatt-hour (kWh) is substantially higher than the average cost of energy in the onshore markets, what features of state regulation or policy facilitate the sale? Second, the developer must secure, or acquire by sale or assignment, appropriate offshore sites for development of the physical resource. Most available offshore wind resources are located in the OCS and will be under federal control for leasing. Developers must secure OCS leases either through successful bids in the initial offering or through a later acquisition or assignment from winning bidders. Offshore wind development requires large areas within which to erect the number of turbines needed, as well as a gathering system of cables and substations, to collect and deliver the output of all the turbines via transmission lines to interconnections with the existing mainland grid. The developer also must obtain rights-of-way to lay cable for its gathering and transmission facilities—on the OCS and across state submerged lands and coastal areas. In the alternative, a new offshore wind transmission system may be built by a third party to connect with multiple wind farms and deliver energy to an onshore point of interconnection. These leasing and project configuration scenarios present many questions. If the offshore wind developer and the transmission facility developer are separate entities, how much coordination is required? What is the appropriate scope of environmental impact studies needed in connection with the OCS leasing process? What are the mechanics for acquiring the necessary property rights and leases between winning bidders and other interested developers? Third, the offshore wind developer, alone or with a third-party transmission developer, must be concerned about the interconnection of the offshore cable to the onshore transmission grid. Most onshore transmission and distribution grids were planned, constructed and operated on the assumption that electricity consumers on the coast are the end of the delivery line. While transmission grids are somewhat more robust at these isolated coastal locations—particularly when large nuclear and fossil generation exists at water’s edge—these more robust coastal grid systems are limited and may be neither geographically nor electrically proximate to offshore wind generation locations. With advances in turbine technology and the overall economics of offshore wind farm development most proposed commercial-scale projects are likely to have generation capacity in the hundreds of megawatts (MWs). Typically, interconnection of offshore wind and related transmission delivery facilities require not only reconfiguration and enlargement of the receiving onshore transmission grid to accept the input of such electric capacity at water’s edge, but also delivery to load centers that may be located a substantial distance inland. Owners of the onshore grid may not be the same as the utility purchaser or other off-taker of the offshore electric energy. The complexities of onshore interconnection raise vexing questions, such as: (i) how to reconfigure and enlarge the grid to interconnect with offshore generation, accept the energy output, and deliver to load centers; and (ii) who should bear the costs of that reconfiguration and enlargement. This Article is intended to provide a helpful roadmap or guidance for major issues in three principal areas—securing a viable purchaser, siting the offshore development farm, and onshore interconnection of the offshore cable. To date, most offshore wind development efforts in the United States occur off the Northeast and Mid-Atlantic coast. This Article highlights the emerging federal-state dynamic in the development of offshore wind generation and illuminates several key uncertainties developers face today

    What more can we learn from PISA tests? A comparative Analysis of the Long-term Dynamics of the Israeli International Educational Achievements

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    One of the most prominent comparative international tests in recent years is conducted by the Programme for International Student Assessment (PISA), which is used to assess students' knowledge of reading comprehension, mathematics, and science. PISA is most known for its goal to compare nations according to a league table ranking system. Israel has taken part in these assessments from its conception and since then it has been gradually decreasing in the world ranking. By 2015 the Israeli students are located between 37-40 out of 70 countries, down from 31-33 in 2000. Using Israel's data throughout the PISA cycles, we aim to offer an alternative comparative view for these international results, based on measures of self-change. These measures show a consistent and significant system-wide improvement of the Israeli educational performance in all three PISA tests since 2000. Not only does this contrast with its downward trend in the international ranking which is biased due to inclusion of more countries, the rate of change was consistently positive over time and surpassing that of its European and American counterparts. Indeed, these measures of change show a general growth of about 23 points over 15 years, which reflects a consistent improvement of 6 to 9 points in average per cycle since 2000 results. In light of these findings, the paper discusses the significance of measurements of change in comparative international tests.

    The Role of Reactive Oxygen Species in Diabetes-Induced Anomalies in Embryos of Cohen Diabetic Rats

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    The role of the antioxidant defense mechanism in diabetesinduced anomalies was studied in the Cohen diabetes-sensitive (CDs) and -resistant (CDr) rats, a genetic model of nutritionally induced type 2 diabetes mellitus. Embryos, 12.5-day-old, of CDs and CDr rats fed regular diet (RD) or a diabetogenic high-sucrose diet (HSD) were monitored for growth retardation and congenital anomalies. Activity of superoxide dismutase (SOD) and catalaselike enzymes and levels of ascorbic acid (AA), uric acid (UA), and dehydroascorbic acid (DHAA) were measured in embryonic homogenates. When fed RD, CDs rats had a decreased rate of pregnancy, and an increased embryonic resorption. CDs embryos were smaller than CDr embryos; 46% were maldeveloped and 7% exhibited neural tube defects (NTDs). When fed HSD, rate of pregnancy was reduced, resorption rate was greatly increased (56%; P < .001), 47.6% of the embryos were retrieved without heart beats, and 27% exhibited NTD. In contrast, all the CDr embryos were normal when fed RD or HSD. Activity of SOD and catalase was not different in embryos of CDs and CDr rats fedRD. When fed HSD, levels of AA were significantly reduced, the ratio DHAA/AA was significantly increased, and SOD activity was not sufficiently increased when compared to embryos of CDr. The reduced fertility of the CDs rats, the growth retardation, and NTD seem to be genetically determined. Maternal hyperglycemia seems to result in environmentally induced embryonic oxidative stress, resulting in further embryonic damage

    Cloned Myogenic Cells Can Transdifferentiate In Vivo into Neuron-Like Cells

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    Background: The question of whether intact somatic cells committed to a specific differentiation fate, can be reprogrammed in vivo by exposing them to a different host microenvironment is a matter of controversy. Many reports on transdifferentiation could be explained by fusion with host cells or reflect intrinsic heterogeneity of the donor cell population. Methodology/Principal Findings: We have tested the capacity of cloned populations of mouse and human muscle progenitor cells, committed to the myogenic pathway, to transdifferentiate to neurons, following their inoculation into the developing brain of newborn mice. Both cell types migrated into various brain regions, and a fraction of them gained a neuronal morphology and expressed neuronal or glial markers. Likewise, inoculated cloned human myogenic cells expressed a human specific neurofilament protein. Brain injected donor cells that expressed a YFP transgene controlled by a neuronal specific promoter, were isolated by FACS. The isolated cells had a wild-type diploid DNA content. Conclusions: These and other results indicate a genuine transdifferentiation phenomenon induced by the host brain microenvironment and not by fusion with host cells. The results may potentially be relevant to the prospect of autologous cell therapy approach for CNS diseases

    Charge transport across metal/molecular (alkyl) monolayer-Si junctions is dominated by the LUMO level

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    We compare the charge transport characteristics of heavy doped p- and n-Si-alkyl chain/Hg junctions. Photoelectron spectroscopy (UPS, IPES and XPS) results for the molecule-Si band alignment at equilibrium show the Fermi level to LUMO energy difference to be much smaller than the corresponding Fermi level to HOMO one. This result supports the conclusion we reach, based on negative differential resistance in an analogous semiconductor-inorganic insulator/metal junction, that for both p- and n-type junctions the energy difference between the Fermi level and LUMO, i.e., electron tunneling, controls charge transport. The Fermi level-LUMO energy difference, experimentally determined by IPES, agrees with the non-resonant tunneling barrier height deduced from the exponential length-attenuation of the current

    Improving the Management of Late-Life Depression in Primary Care: Barriers and Facilitators

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    The objectives of this study were to elicit Canadian health professionals' views on the barriers to identifying and treating late-life depression in primary care settings and on the solutions felt to be most important and feasible to implement. A consensus development process was used to generate, rank, and discuss solutions. Twenty-three health professionals participated in the consensus process. Results were analysed using quantitative and qualitative methods. Participants generated 12 solutions. One solution, developing mechanisms to increase family physicians' awareness of resources, was highly ranked for importance and feasibility by most participants. Another solution, providing family physicians with direct mental health support, was highly ranked as important but not as feasible by most participants. Deliberations emphasized the importance of case specific, as needed support based on the principles of shared care. The results suggest that practitioners highly value collaborative care but question the feasibility of implementing these principles in current Canadian primary care contexts
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