Openness in Scientific Research: A Historical and Philosophical Perspective

Openness is widely regarded as a pillar of scientific ethics because it promotes reproducibility and progress in science and benefits society. However, the sharing of scientific information can sometimes adversely impact the interests of human research participants, human communities or populations, scientists, and private research sponsors; and may threaten national security. Because openness may conflict with other important social values, solutions to ethical and policy dilemmas should include meaningful input from those who are impacted by the sharing and use of scientific information, including research participants, communities, and the public. Data sharing and use policies should be reviewed and revised periodically to account for ongoing changes in science, technology, and society

Environmental Health Research Involving Human Subjects: Ethical Issues

This article reviews some of the ethical issues that arise in environmental health research with human subjects, such as minimizing risks to subjects, balancing benefits and risks in research, intentional exposure studies with human subjects, protecting third parties in research, informing subjects about environmental hazards, communicating health information to subjects, and protecting privacy and confidentiality

The clinical investigator-subject relationship: a contextual approach

Abstract Background The nature of the relationship between a clinical investigator and a research subject has generated considerable debate because the investigator occupies two distinct roles: clinician and scientist. As a clinician, the investigator has duties to provide the patient with optimal care and undivided loyalty. As a scientist, the investigator has duties to follow the rules, procedures and methods described in the protocol. Results and conclusion In this article, I present a contextual approach to the investigator-subject relationship. The extent of the investigator's duty to provide the patient/subject with clinical care can vary from one situation to the next, as a function of several factors, including: the research design, benefits and risks of the research; the subject's reasonable expectations, motivations, and vulnerabilities; the investigator's ability to benefit the subject; and the investigator's prior relationship with the subject. These and other factors need to be considered when determining the clinical investigator's obligations to provide clinical care to human research subjects. In some research contexts, the investigator has extensive clinical obligations to the patient/subject; in others, the investigator has minimal ones.</p

Managing Peanut Allergies In Schools: Ethical And Policy Issues

Protecting children with peanut allergies from harm poses difficult ethical dilemmas for school administrators. Some schools have responded to the peanut allergy problem by implementing bans on peanuts and peanut products, thereby sparking outrage and protests from some parents. School administrators should carefully consider how best to protect allergic children while taking into consideration the interests of non-allergic children, their parents and practical considerations. While it is not realistic to expect that a school setting can be risk-free, every reasonable effort should be made to protect allergic children from harm in order to promote their health and educational attainment

Genetic modification and genetic determinism

In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument. We then demonstrate that each of these arguments against genetic modification assumes a strong version of genetic determinism. Since these strong deterministic assumptions are false, the arguments against genetic modification, which assume and depend upon these assumptions, are therefore unsound. Serious discussion of the morality of genetic modification, and the development of sound science policy, should be driven by arguments that address the actual consequences of genetic modification for individuals and society, not by ones propped up by false or misleading biological assumptions

The acute effects of various types of stretching (static, dynamic, ballistic, and no stretch) of the iliopsoas on 40-yard sprint times in non-athletes

The purpose of this study was to determine the effect of static, ballistic, dynamic, and no stretching immediately prior to a 40-yard sprint in college students. There were 35 healthy subjects (22 male and 13 female) between the ages of 24 and 37 (Mean = 26.46 yrs, SD = 2.99 yrs) who participated. The experiment consisted of running 4, 40-yard sprint trials immediately following 1 of 4 different stretching protocols. Prior to each 40- yard sprint trial, a 5-minute warm up was performed at 3.5 mph on a treadmill. Each subject received each of the four techniques in a randomized order and ran a baseline sprint prior to each stretching protocol. In each protocol, subjects received one of four stretching techniques: ballistic, dynamic, static, no stretch and immediately ran a timed 40-yard sprint post stretch. The trials were completed within a 2 week time period allowing 48-72 hours between each trial. In the no stretch condition, subjects improved significantly from pre to post sprint times (