Cooperation after War: International Development in Bosnia, 1995 to 1999

This paper discusses how predispositions, incentives, the number and heterogeneity of participants, and leadership (Faerman et al. 2001) jointly influenced the international effort to develop Bosnia and Herzegovina. International coalitions, task forces, and advisory groups are increasingly charged with implementing reforms following civil conflict. This requires a complex web of interorganizational relationships among NGOS, donors and host nations at both global and ‘ground’ levels. To better understand development assistance, attention must be paid to the relationships between these varied players. We find that four factors influenced relationships between policy, donor, and implementing organizations; and those strained relationships, in turn, affected development success. The paper draws on interviews, conducted in Bosnia, with 43 development professionals, observation of development meetings in Tuzla and Sarajevo, and review of related documents from international development programs.international development, interorganizational relationships and cooperation

Murine terminal deoxynucleotidyl transferase: cellular distribution and response to cortisone

The mouse thymus contains two forms of terminal deoxynucleotidyl transferase (TdT) which are distinguishable by the salt concentration necessary to elute them from a phosphocellulose column, by their distrubtion among the thymocyte subpopulations, and by their sensitivity to cortisone treatment. In the whole thymus the later eluting peak (peak II) is the predominant one with about 3-10% of the total activity appearing in peak I. Both peak I and peak II activities are most sensitively assayed by the polymerization of dGMP onto an oligo(dA) primer. The minor population of thymocytes which is less dense and cortisone-resistant contains a higher specific activity of peak I TdT. The majority of TdT activity is, however, found in the major population of thymocytes which occurs in the center region of a bovine serum albumin gradient and is cortisone-sensitive. A very low level of an activity indistinguishable from peak II TdT activity is also detected in the mouse bone marrow. Other tissues, such as spleen, liver, heart, and brain lack detectable amounts of TdT activity

Cooperation after war

This paper discusses how predispositions, incentives, the number and heterogeneity of participants, and leadership (Faerman et al. 2001) jointly influenced the international effort to develop Bosnia and Herzegovina. International coalitions, task forces, and advisory groups are increasingly charged with implementing reforms following civil conflict. This requires a complex web of interorganizational relationships among NGOS, donors and host nations at both global and "ground" levels. To better understand development assistance, attention must be paid to the relationships between these varied players. We find that four factors influenced relationships between policy, donor, and implementing organizationsand those strained relationships, in turn, affected development success. The paper draws on interviews, conducted in Bosnia, with 43 development professionals, observation of development meetings in Tuzla and Sarajevo, and review of related documents from international development programs

"Isn't All of Oncology Hermeneutic?"

In this paper, we describe an event during a pediatric oncology research meeting that prompted the discussion of the ways in which hermeneutics brings a different kind of understanding to both research and practice. We claim that oncology is the practical science of handling natural science research and as such practice in oncology is deeply hermeneutic in character in its recognition of the importance, vitality, and generativity of the “individual case†even in the face of amassed, verified, and aggregate knowledge that is given from the natural science research. Oncology is always contingent, next case handling, and is not identifiable simply as something determined and guided by natural sciences alone. In the face of this, we propose that there is an obvious, profound, and natural fit of hermeneutic research in understanding the lives, relationships, suffering, and experiences that are affected by cancer.   Keywords: childhood cancer, Gadamer, hermeneutics, pediatric oncology, Robert Buckman Â

A case study of polar cap sporadic-E layer associated with TEC variations

The Sporadic-E (Es) layer is an often-observed phenomenon at high latitudes; however, our understanding of the polar cap Es layer is severely limited due to the scarce number of measurements. Here, the first comprehensive study of the polar cap Es layer associated with Global Positioning System (GPS) Total Electron Content (TEC) variations and scintillations is presented with multiple measurements at Resolute, Canada (Canadian Advanced Digital Ionosonde (CADI), Northward-looking face of Resolute Incoherent-Scatter Radar (RISR-N), and GPS receiver). According to the joint observations, the polar cap Es layer is a thin patch structure with variously high electron density, which gradually develops into the lower E region (~100 km) and horizontally extends >200 km. Moreover, the TEC variations produced by the polar cap Es layer are pulse-like enhancements with a general amplitude of ~0.5 TECu and are followed by smaller but rapid TEC perturbations. Furthermore, the possible scintillation effects likely associated with the polar cap Es layer are also discussed. As a consequence, the results widely expand our understanding on the polar cap Es layer, in particular on TEC variations

GNSS Differential Code Bias Determination Using Rao‐Blackwellized Particle Filtering

The Assimilative Canadian High Arctic Ionospheric Model (A-CHAIM) is a near-real-time data assimilation model of the high latitude ionosphere, incorporating measurements from many instruments, including slant Total Electron Content measurements from ground-based Global Navigation Satellite System (GNSS) receivers. These measurements have receiver-specific Differential Code Biases (DCB) which must be resolved to produce an absolute measurement, which are resolved simultaneously with the ionospheric state using Rao-Blackwellized particle filtering. These DCBs are compared to published values and to DCBs determined using eight different Global Ionospheric Maps (GIM), which show small but consistent systematic differences. The potential cause of these systematic biases is investigated using multiple experimental A-CHAIM test runs, including the effect of plasmaspheric electron content. By running tests using the GIM-derived DCBs, it is shown that using A-CHAIM DCBs produces the lowest overall error, and that using GIM DCBs causes an overestimation of the topside electron density which can exceed 100% when compared to in situ measurements from DMSP

Double-blind, placebo-controlled, randomized trial of octreotide in malignant bowel obstruction

Context Does octreotide reduce vomiting in cancer-associated bowel obstruction? Objectives To evaluate the net effect of adding octreotide or placebo to standardized therapies on the number of days free of vomiting for populations presenting with vomiting and inoperable bowel obstruction secondary to cancer or its treatment. Methods Twelve services enrolled people with advanced cancer presenting with vomiting secondary to bowel obstruction where surgery or anti-cancer therapies were not indicated immediately. In a double-blind study, participants were randomized to placebo or octreotide (600 μg/24 hours by infusion). Both arms received standardized supportive therapy (infusion of ranitidine [200 mg/24 hours], dexamethasone [8 mg/24 hours], and parenteral hydration [10-20 mL/kg/24 hours]). The primary outcome was patient-reported days free of vomiting at 72 hours. Results In a study that recruited to the numbers identified in its power calculation, 87 participants provided data at 72 hours (45, octreotide arm). Seventeen people (octreotide) and 14 (placebo) were free of vomiting for 72 hours (P = 0.67). Mean days free of vomiting were 1.87 (SD 1.10; octreotide) and 1.69 (SD 1.15; placebo; P = 0.47). An adjusted multivariate regression of the incidence of vomiting over the study showed a reduced number of episodes of vomiting in the octreotide group (incidence rate ratio = 0.40; 95% CI: 0.19-0.86; P = 0.019); however, people in the octreotide arm were 2.02 times more likely to be administered hyoscine butylbromide (P = 0.004), potentially reflecting increased colicky pain. Conclusion Although there was no reduction in the number of days free of vomiting, the multivariate analysis suggests that further study of somatostatin analogues in this setting is warranted