Prevalence of pneumococcal carriage by age group in a peri-urban Nigerian Community.

<p>Prevalence of pneumococcal carriage by age group in a peri-urban Nigerian Community.</p

Hazard ratios for first acquisition of selected serotypes and serotype groups in infants from vaccinated and control villages in the main (post-vaccination) study. Comparisons of each arm with the earlier baseline study are also included.

*<p>9 children in the vaccinated villages had serotype 7F isolates, all of these were in the post-vaccination survey. Hazard ratios comparing the hazards for first acquisition of pneumococci with those found in the pre-vaccination survey in each arm of the trial are also shown.</p

Prevalence of nasopharyngeal carriage of pneumococcus by infant age category in a peri urban Nigerian Community.

<p>Prevalence of nasopharyngeal carriage of pneumococcus by infant age category in a peri urban Nigerian Community.</p

Characteristics of infants in the study by village group.

<p>Note:</p>*<p>includes Serere, Manjago and Sarahule groups present in very small numbers in the villages where the study took place.</p>+<p>refers to carriage at any time in infants up to 8 weeks of age. Numbers in parenthesis are percentages except as specified for birth weight.</p

Carriage of selected pneumococcal serotypes isolated at any time during the first 8 weeks of life stratified by study arm.

<p>Note: Figures for vaccine serotypes, NT and the 11 most frequently isolated non-vaccine serotypes are shown.</p

Figure 2

<p>A. Proportion of infants who carried S. pneumoniae at any time in first 8 weeks of life. B. Point prevalence of pneumococcal carriage overall in infants by age and study arm. C. Point prevalence of vaccine serotype carriage by age and study arm. D. Point prevalence of non vaccine serotype carriage by age and study arm.</p

Clustering of STs by use of the minimum spanning tree.

<p>Each circle represents an ST. The area of each circle corresponds to the number of isolates. Thick, short, solid lines connect single locus variants; thin longer solid lines connect double locus variants and broken lines connect three or more locus variants. Texts in red and inside the circles are the serotypes.</p

Multivariable odds ratios determined by logistic regression for pneumococcal carriage and risk factors.

<p>*OR-Odds Ratio from Logistic regression model.</p><p>**Adjusted for clustering.</p

Kaplan-Meier survival curves for time to first acquisition of different serotype groups in the pre-vaccination and post-vaccination surveys by study arm.

<p>Kaplan-Meier survival curves for time to first acquisition of different serotype groups in the pre-vaccination and post-vaccination surveys by study arm.</p

Pneumococcal Carriage and approximate vaccine coverage by age.

<p><b>PCV</b>-pneumococcal conjugate vaccine; <b>NT</b>-Non Typeable; <b>PCV7 serotypes</b>: 4, 6B, 9V, 14, 18C, 19F, 23F; <b>PCV10 serotypes</b>: PCV7+ 1, 5, 7F; <b>PCV13 serotypes</b>: PCV10+ 3, 6A, 19A.</p