The distribution of percent of CMV-specific T cells in CMV-seronegative and CMV-seropositive, HIV-uninfected subjects.

<p>The distribution of percent of CMV-specific T cells in CMV-seronegative and CMV-seropositive, HIV-uninfected subjects.</p

Percentage of pp65-specific interferon-γ+ CD4+ T cells in antiretroviral treated subjects with undetectable viral loads and in untreated HIV infected subjects.

<p>Percentage of pp65-specific interferon-γ+ CD4+ T cells in antiretroviral treated subjects with undetectable viral loads and in untreated HIV infected subjects.</p

Percentage of pp65-specific interferon-γ + CD4+ T cells in antiretroviral treated subjects with undetectable viral loads and HIV seronegative subjects.

<p>Percentage of pp65-specific interferon-γ + CD4+ T cells in antiretroviral treated subjects with undetectable viral loads and HIV seronegative subjects.</p

CMV-specific T cell responses in HIV uninfected and infected adults.

<p>NOTE. Median values and interquartile ranges are shown. All subjects contributed pp65-specific IFN-γ-bright data (n = 685), while only a subset contributed pp65 and IE data (see text). IE data were not available from the recently infected subjects. The combined pp65 and IE interferon-γ/IL2 data reflect the sum of all possible response (IFN-γ alone, IL2 alone and IFN-γ/IL2) to each of the CMV protein.</p

Baseline characteristics.

<p><b>NOTE.</b> Median values and interquartile ranges are shown unless otherwise noted.</p

The distribution of the CMV-specific CD4+ and CD8+ T cell responses (background corrected) in three unique groups: (1) HIV-seronegative, CMV-seropositive, (2) established chronic untreated HIV infection, and (3) antiretroviral-treated infection with undetectable plasma HIV RNA levels.

<p>The IE IFN-γ-bright levels are shown in panel A (CD4+ T cells) and panel B (CD8+ T cells). The combined pp65 and IE IFN-γ/IL2 data are shown in panels C (CD4+ T cells) and panel D (CD8+ T cells). The data in panels C and D reflect the sum of all possible response (IFN-γ alone, IL2 alone, or IFN-γ/IL2) to each of the CMV proteins. Standard gating was used for dual cytokine data.</p

The distribution of pp65 IFN-γ-bright CD4+ and CD8+ T cell responses (background corrected) in four unique groups: (1) HIV-seronegative, CMV-seropositive, (2) acute and recent untreated HIV infection, (3) established chronic untreated HIV infection, and (4) antiretroviral-treated infection with undetectable plasma HIV RNA levels.

<p>The distribution of pp65 IFN-γ-bright CD4+ and CD8+ T cell responses (background corrected) in four unique groups: (1) HIV-seronegative, CMV-seropositive, (2) acute and recent untreated HIV infection, (3) established chronic untreated HIV infection, and (4) antiretroviral-treated infection with undetectable plasma HIV RNA levels.</p