11 research outputs found

    Top five GO annotations whose UTRs are significantly shorter than average

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    <p>Biological process (BP), molecular function (MF), and cellular component (CC).</p

    Relationship between ORF length and transcript length.

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    <p>Refseq length in nucleotides is plotted against ORF length in nucleotides. The black line is the linear least squares fit. It has the parameters mRNA = 1.03 (ORF)+1263 (R<sup>2</sup> = 0.74).</p

    Association between cDNA clones and human genes

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    <p>Since these microarrays contained duplicated spots, the parentheses represent clones after averaging.</p

    Calibration between bootstrap value and true positive rate.

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    <p>The bootstrap value is plotted against the true positive rate for bootstrap values from 0 to 0.6. The least squares fit to a sigmoidal equation is shown by a solid line with the parameters y = −0.07563+1.09892/(1+e <sup>(0.15928−x)/0.08257</sup>).</p

    Solute carrier family 2 (facilitated glucose transporter), member 1 (<i>SLC2A1</i>) gene.

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    <p>The <i>SLC2A1</i> gene is pictured schematically. The transcribed portion of the gene is shown with the filled boxes representing exons. The ORF is represented by the taller boxes. The genomic positions of four cDNA clones that map only to the <i>SLC2A1</i> gene, and a proposed novel <i>SLC2A1</i> transcript, are shown relative to the <i>SLC2A1</i> gene. The transcript length measured for each clone is shown in parentheses.</p

    Deconvolution kernel.

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    <p>The stereotypical peak used as the deconvolution kernel to identify potential peaks is shown.</p

    Example length profile with deconvolution results.

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    <p>An example length profile is shown in blue. The normalized ratio from each length fraction is plotted against the length fractions in order, where the first length fraction is the one with the highest gel mobility. The rolling baseline is shown in green, and the deconvolution result is shown in red.</p

    Calibrating the relationship between gel mobility and transcript length.

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    <p>The precise gel mobilities of all peaks from gold standard genes are plotted against the natural log of the sum of their matching Refseq length and an estimated poly(A) tail length of 225 nucleotides. The least squares fit to a line is shown by a black line with the parameters y = 0.054731 x+5.997276 (R<sup>2</sup> = 0.99). Closed circles represent points used to determine the calibration line. Points shown by open circles were excluded from the least squares calculation.</p
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