283 research outputs found
Profiling Chemicals Based on Chronic Toxicity Results from the U.S. EPA ToxRef Database
Attribute filters allow enhancement and extraction of features without distorting their borders, and never introduce new image features. These are highly desirable properties in biomedical imaging, where accurate shape analysis is paramount. However, setting the attribute-threshold parameters has to date only been done manually. This paper explores simple, fast and automated methods of computing attribute threshold parameters based on image segmentation, thresholding and data clustering techniques. Though several techniques perform well on blood-vessel filtering, the choice of technique appears to depend on the imaging mode.
The effect of RO3201195 and a pyrazolyl ketone P38 MAPK inhibitor library on the proliferation of Werner syndrome cells
No description supplie
Multiple strain-induced phase transitions in LaNiO3 thin films
Weber, M.C. et al.Strain effects on epitaxial thin films of LaNiO3 grown on different single crystalline substrates are studied by Raman scattering and first-principles simulation. New Raman modes, not present in bulk or fully-relaxed films, appear under both compressive and tensile strains, indicating symmetry reductions. Interestingly, the Raman spectra and the underlying crystal symmetry for tensile and compressively strained films are different. Extensive mapping of LaNiO3 phase stability is addressed by simulations, showing that a variety of crystalline phases are indeed stabilized under strain which may impact the electronic orbital hierarchy. The calculated Raman frequencies reproduce the principal features of the experimental spectra, supporting the validity of the multiple strain-driven structural transitions predicted by the simulations.J.K., M.W., M.G., and J.I. acknowledge support from
the National Research Fund, Luxembourg through a Pearl
grant (Grant No. FNR/P12/4853155). ICMAB-CSIC authors
acknowledge financial support from the Spanish Ministry of
Economy and Competitiveness, through the “Severo Ochoa”
Programme for Centres of Excellence in R&D (SEV-2015-
0496) and the MAT2014-56063-C2-1-R and MAT2013-
40581-P projects, and from Generalitat de Catalunya (2014
SGR 734). UB authors acknowledge financial support from the
Spanish Ministry of Economy and Competitiveness, project
MAT2013-41506-P and from Generalitat de Catalunya (2014
SGR 672).Peer reviewe
Informing Selection of Nanomaterial Concentrations for ToxCast in Vitro Testing Based on Occupational Exposure Potential
Background: Little justification is generally provided for selection of in vitro assay testing concentrations for engineered nanomaterials (ENMs). Selection of concentration levels for hazard evaluation based on real-world exposure scenarios is desirable
Environmental Impact on Vascular Development Predicted by High-Throughput Screening
Background: Understanding health risks to embryonic development from exposure to environmental chemicals is a significant challenge given the diverse chemical landscape and paucity of data for most of these compounds. High-throughput screening (HTS) in the U.S. Environmental Protection Agency (EPA) ToxCast™ project provides vast data on an expanding chemical library currently consisting of > 1,000 unique compounds across > 500 in vitro assays in phase I (complete) and Phase II (under way). This public data set can be used to evaluate concentration-dependent effects on many diverse biological targets and build predictive models of prototypical toxicity pathways that can aid decision making for assessments of human developmental health and disease
The Vehicle, 1965, Vol. 7
Vol. 7
Table of Contents
CommentaryElaine Lancepage 3
Lost Island and The Unseen SeaDaun Alan Leggpage 5
ElegyWilliam Mosierpage 6
AwayDavid Dixpage 7
DulceyRoberta Mathewspage 8
Alarum Tuam JonneDavid Walkerpage 11
Little BrotherSteve Gibbspage 13
River RunningDaun Alan Leggpage 15
PortraitRobert D. Thomaspage 16
The RockRoger Lewis Hudsonpage 17
Jarman HospitalElaine Lancepage 18
Of Domes and DiamondsDwight Ashbypage 19
Friday NightRoger J. Barrypage 20
MurderHelen Coxpage 23
Vigil SongDaun Alan Leggpage 24
Had You But Been the OneDavid Helmpage 25
To A Useless WeaponDarlene Brewerpage 25
Out of the NightPat Hartpage 26
La MortAdrian Beardpage 28
Mrs. Milton\u27s LamentBob Millerpage 30
Cockle CoveSusan McCabepage 31
Loss of VirtueJim Rinnertpage 32
The KeepsakeDwight Ashbypage 33
The RuinsRoger Lewis Hudsonpage 35
Ante Major OdysseyDaun Alan Leggpage 38
ReligionAnthony Barrettepage 39
All JoyJim Rinnertpage 40
SesameElaine Lancepage 40
CenterpieceDwight Ashbypage 41
A Great White WaveJohn Rhodespage 42
QueryElaine Lancepage 44
PistachioRita Salyerspage 45
FacadeKathleen McCormackpage 46
Winter Wisp AwaySteve Gibbspage 46
ScenarioDavid Dixpage 47
Damn-GodSteve Gibbspage 48
AccidentElaine Lancepage 48https://thekeep.eiu.edu/vehicle/1013/thumbnail.jp
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