Demographic Characteristics and Baseline Values.

<p>Values are mean ± SD except otherwise stated.</p

30- and 60-Minute Massage Protocols.

<p>*Accounting for time spent in transition including the welcome, transition to the massage room, taking off jewelry, and other preparatory activities.</p

Improvement in WOMAC-Global Scores at Assigned Doses of Massage.

<p>Improvement in WOMAC-Global Scores at Assigned Doses of Massage.</p

Mean change (95% CI) in outcomes at 8-weeks post-baseline (primary endpoint).

<p>Values are mean with 95% confidence intervals; negative values indicate improvement;</p>†<p>Significant (non-overlap) compared to Usual Care;</p>‡<p>Significant (non-overlap) compared to Group 1.</p

Dose-Response Curve.

<p>Dose-response curve plotting dose (total minutes over the course of 8-weeks of massage) (x-axis) vs. improvement (change in WOMAC Global scores after 8-weeks). Dose-response effects plateaued at 480-minutes (Group 3), with no significant improvements noted in the 720-minute (Group 4) dose.</p