Adjusted hazard ratios for all-cause mortality, by self-rated health category, sex and increasing length of follow-up (referent: excellent SRH, n = 7,959).

<p>95% confidence intervals are given for hazard ratios after 10 years, 20 years and maximum follow-up. Adjustment for age, marital status, educational level, smoking status, medical history, medication status, fasting blood glucose and systolic blood pressure.</p

Adjusted hazard ratios for all-cause mortality by self-rated health category and sex, n = 7,959, 5 Swiss towns, 1977–79, ≥16 years at baseline.

<p>*continuous variable.</p><p>Model 1 (basic): age; Model 2 (socio-demographic): basic model + education, marital status; Model 3 (lifestyle): socio-demographic model + smoking status; Model 4 (medical history): lifestyle model + disease and medication status; Model 5 (clinical): medical history model + fasting blood glucose, systolic blood pressure.</p><p>95% Confidence Intervals (95% CI) of all models (including Model 2–4) are given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030795#pone.0030795.s002" target="_blank">Table S2</a> (Supporting Information).</p

NRP 1A participants (by study participation status) vs. general Swiss population, individuals aged 16–69 years.

<p>*N = 8,251; 92 participants with invalid date of birth and 288 participants exceeding the official upper limit of age excluded.</p><p>**figures for the general population are from the 1980 census (Swiss Federal Statistical Office).</p

Characteristics of linked NRP 1A participants by self-rated health category and sex, n = 8,008, 5 Swiss towns, 1977–79, ≥16 years at baseline.

<p>*for the variables marital status, medical history and medication, blood glucose and blood pressure.</p

Lifestyle of obese and/or heavy smokers by sex, multinomial logistic regression: reference group normal-weight never smokers (adjusted for sociodemographic factors, age, and survey), weighted according to the general population of Switzerland.

<p>Lifestyle of obese and/or heavy smokers by sex, multinomial logistic regression: reference group normal-weight never smokers (adjusted for sociodemographic factors, age, and survey), weighted according to the general population of Switzerland.</p

Prevalence of smokers by status additionally stratified by BMI for heavy and never smokers SHS 2012.

<p>Men n = 35,880 (missing n = 2,949) and women n = 44,142 (missing n = 2,604). BMI (Body Mass Index, kg/m²): underweight <18.5, normal-weight ≥18.5–<25, overweight ≥25–<30, obesity ≥30; Smoking status: never, former, light (1–9 cigarettes per day), moderate (10–19), heavy smoker (>19); SHS: Swiss Health Survey; Results are weighted according to the general population of Switzerland.</p

Demographic characteristic, BMI category, smoking status, and survey.

<p>Demographic characteristic, BMI category, smoking status, and survey.</p

Survival of men and women by self-rated health category, Switzerland 1977–1979, followed up until 2008: Kaplan-Meier curves by sex (N = 8,008).

<p>Number of persons at risk is shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030795#pone.0030795.s003" target="_blank">Table S3</a> (Supporting Information).</p

Estimated absolute numbers (N) and proportions (%^*) for smoking status, BMI, and selected smoking-BMI-combinations in Switzerland 2012.

<p>Estimated absolute numbers (N) and proportions (%^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0148563#t002fn002" target="_blank">*</a>}) for smoking status, BMI, and selected smoking-BMI-combinations in Switzerland 2012.</p

Chart for absolute 10-year risk of fatal cardiovascular disease based on the new model using total cholesterol.

<p>9,446 participants of the Swiss MONICA study conducted 1983–92, ages 25–74 years at baseline. MONICA: MONItoring of trends and determinants in CArdiovascular disease, entire population with full follow-up Each risk percentage is calculated using a combination of given risk factor values. E.g., a man aged 65, smoker, with a systolic blood pressure of 180 and a total cholesterol of 6 mmol/L has an absolute risk (within the next 10 years) of fatal CVD of 14%.</p