Phase transitions and ferroelectric properties in BiScO3-Bi(Zn1/2Ti1/2)O3-BaTiO3 solid solutions

Ceramics solid solutions within the ternary perovskite system Bi(Zn1/2Ti1/2)O3-BiScO3-BaTiO3 were synthesized via solid-state processing techniques. The crystal structure of sintered ceramics was analyzed by x-ray diffraction. A stable perovskite phase was obtained for all compositions with a BaTiO3 content greater than 50 mol %. Furthermore, a change in symmetry from pseudocubic to tetragonal was observed as the mole fraction of BaTiO3 increased. Dielectric measurements show a dielectric anomaly associated with a phase transformation over the temperature range of 30 °C–210 °C for all compositions. Examination of the polarization hysteresis behavior revealed weakly nonlinear hysteresis loops. With these data, ferroelectric phase diagrams were derived showing the transition between the pseudocubic relaxor behavior to the tetragonal normal ferroelectric behavior. This transition was also correlated with changes in the diffuseness parameter

Spike propagation through the dorsal root ganglia in an unmyelinated sensory neuron: a modeling study

Unmyelinated C-fibers are a major type of sensory neurons conveying pain information. Action potential conduction is regulated by the bifurcation (T-junction) of sensory neuron axons within the dorsal root ganglia (DRG). Understanding how C-fiber signaling is influenced by the morphology of the T-junction and the local expression of ion channels is important for understanding pain signaling. In this study we used biophysical computer modeling to investigate the influence of axon morphology within the DRG and various membrane conductances on the reliability of spike propagation. As expected, calculated input impedance and the amplitude of propagating action potentials were both lowest at the T-junction. Propagation reliability for single spikes was highly sensitive to the diameter of the stem axon and the density of voltage-gated Na+ channels. A model containing only fast voltage-gated Na+ and delayed-rectifier K+ channels conducted trains of spikes up to frequencies of 110 Hz. The addition of slowly activating KCNQ channels (i.e., KV7 or M-channels) to the model reduced the following frequency to 30 Hz. Hyperpolarization produced by addition of a much slower conductance, such as a Ca²+-dependent K+ current, was needed to reduce the following frequency to 6 Hz. Attenuation of driving force due to ion accumulation or hyperpolarization produced by a Na+-K+ pump had no effect on following frequency but could influence the reliability of spike propagation mutually with the voltage shift generated by a Ca²+-dependent K+ current. These simulations suggest how specific ion channels within the DRG may contribute toward therapeutic treatments for chronic pain

Innovation as a Nonlinear Process, the Scientometric Perspective, and the Specification of an "Innovation Opportunities Explorer"

The process of innovation follows non-linear patterns across the domains of science, technology, and the economy. Novel bibliometric mapping techniques can be used to investigate and represent distinctive, but complementary perspectives on the innovation process (e.g., "demand" and "supply") as well as the interactions among these perspectives. The perspectives can be represented as "continents" of data related to varying extents over time. For example, the different branches of Medical Subject Headings (MeSH) in the Medline database provide sources of such perspectives (e.g., "Diseases" versus "Drugs and Chemicals"). The multiple-perspective approach enables us to reconstruct facets of the dynamics of innovation, in terms of selection mechanisms shaping localizable trajectories and/or resulting in more globalized regimes. By expanding the data with patents and scholarly publications, we demonstrate the use of this multi-perspective approach in the case of RNA Interference (RNAi). The possibility to develop an "Innovation Opportunities Explorer" is specified.Comment: Technology Analysis and Strategic Management (forthcoming in 2013

Nuclear Shell Model Calculations of Neutralino-Nucleus Cross Sections for Silicon 29 and Germanium 73

We present the results of detailed nuclear shell model calculations of the spin-dependent elastic cross section for neutralinos scattering from \si29 and \ge73. The calculations were performed in large model spaces which adequately describe the configuration mixing in these two nuclei. As tests of the computed nuclear wave functions, we have calculated several nuclear observables and compared them with the measured values and found good agreement. In the limit of zero momentum transfer, we find scattering matrix elements in agreement with previous estimates for \si29 but significantly different than previous work for \ge73. A modest quenching, in accord with shell model studies of other heavy nuclei, has been included to bring agreement between the measured and calculated values of the magnetic moment for \ge73. Even with this quenching, the calculated scattering rate is roughly a factor of 2 higher than the best previous estimates; without quenching, the rate is a factor of 4 higher. This implies a higher sensitivity for germanium dark matter detectors. We also investigate the role of finite momentum transfer upon the scattering response for both nuclei and find that this can significantly change the expected rates. We close with a brief discussion of the effects of some of the non-nuclear uncertainties upon the matrix elements.Comment: 31 pages, figures avaiable on request, UCRL-JC-11408

Empirical Models for Dark Matter Halos. III. The Kormendy relation and the log(rho_e)-log(R_e) relation

We have recently shown that the 3-parameter density-profile model from Prugniel & Simien provides a better fit to simulated, galaxy- and cluster-sized, dark matter halos than an NFW-like model with arbitrary inner profile slope gamma (Paper I). By construction, the parameters of the Prugniel-Simien model equate to those of the Sersic R^{1/n} function fitted to the projected distribution. Using the Prugniel-Simien model, we are therefore able to show that the location of simulated (10^{12} M_sun) galaxy-sized dark matter halos in the _e-log(R_e) diagram coincides with that of brightest cluster galaxies, i.e., the dark matter halos appear consistent with the Kormendy relation defined by luminous elliptical galaxies. These objects are also seen to define the new, and equally strong, relation log(rho_e) = 0.5 - 2.5log(R_e), in which rho_e is the internal density at r=R_e. Simulated (10^{14.5} M_sun) cluster-sized dark matter halos and the gas component of real galaxy clusters follow the relation log(rho_e) = 2.5[1 - log(R_e)]. Given the shapes of the various density profiles, we are able to conclude that while dwarf elliptical galaxies and galaxy clusters can have dark matter halos with effective radii of comparable size to the effective radii of their baryonic component, luminous elliptical galaxies can not. For increasingly large elliptical galaxies, with increasingly large profile shapes `n', to be dark matter dominated at large radii requires dark matter halos with increasingly large effective radii compared to the effective radii of their stellar component.Comment: AJ, in press. (Paper I can be found at astro-ph/0509417