Biomarkers identified for TNBC and ER⁺HER2^-BC.

<p>Biomarkers identified for TNBC and ER⁺HER2^-BC.</p

An approach to select DEGs (protein coding genes) identified by UQ-pgQ2* and <i>DESeq2</i>.

<p>An approach to select DEGs (protein coding genes) identified by UQ-pgQ2* and <i>DESeq2</i>.</p

Summary of normalization methods and software packages used.

<p>Summary of normalization methods and software packages used.</p

Determining an optimal |logFC|** by observed FPR.

<p>An observed FPR based on all of 35203 genes is computed given a |logFC| cutoff in parenthesis.</p

Hierarchical clustering heatmaps of BC based on the DESeq-normalized gene expression levels.

<p>The genes with similar expression patterns are clustered together. The up-regulated genes are in red and the down-regulated genes are in green. (A) A heatmap based on gene expression levels of 1,693 DEGs uniquely identified in TNBC data. (B) A heatmap based on gene expression of 2,299 DEGs uniquely identified in ER⁺HER2^-BC data.</p

The DEGs are associated with cancer biology identified by IPA.

<p>The DEGs are associated with cancer biology identified by IPA.</p