12 research outputs found
S-duality as a beta-deformed Fourier transform
An attempt is made to formulate Gaiotto's S-duality relations in an explicit
quantitative form. Formally the problem is that of evaluation of the Racah
coefficients for the Virasoro algebra, and we approach it with the help of the
matrix model representation of the AGT-related conformal blocks and Nekrasov
functions. In the Seiberg-Witten limit, this S-duality reduces to the Legendre
transformation. In the simplest case, its lifting to the level of Nekrasov
functions is just the Fourier transform, while corrections are related to the
beta-deformation. We calculate them with the help of the matrix model approach
and observe that they vanish for beta=1. Explicit evaluation of the same
corrections from the U_q(sl(2)) infinite-dimensional representation formulas
due to B.Ponsot and J.Teshner remains an open problem.Comment: 21 page
A spontaneously active focus drives a model atrial sheet more easily than a model ventricular sheet
Effects of anisotropy on the development of cardiac arrhythmias associated with focal activity
Electrical interactions between a real ventricular cell and an anisotropic two-dimensional sheet of model cells
Determinants of action potential initiation in isolated rabbit atrial and ventricular myocytes
A new technique for fabricating three-dimensional micro- and nanostructures of various shapes
Role of protein kinase C in anterior pituitary hormone release
The effects of intercellular coupling conductance on the activity of two electrically coupled isolated rabbit sinoatrial nodal cells were investigated. A computer-controlled version of the “coupling clamp” technique was used in which isolated sinoatrial nodal cells, not physically in contact with each other, were electrically coupled at various values of ohmic coupling conductance, mimicking the effects of mutual interaction by electrical coupling through gap junctional channels. We demonstrate the existence of four types of electrical behavior of coupled spontaneously active cells. As the coupling conductance is progressively increased, the cells exhibit: (a) independent pacemaking at low coupling conductances, (b) complex dynamics of activity with mutual interactions, (c) entrainment of action potential frequency at a 1:1 ratio with different action potential waveforms, and (d) entrainment of action potentials at the same frequency of activation and virtually identical action potential waveforms. The critical value of coupling conductance required for 1:1 frequency entrainment was <0.5 nS in each of the five cell pairs studied. The common interbeat interval at a relatively high coupling conductance (10 nS), which is sufficient to produce entrainment of frequency and also identical action potential waveforms, is determined most by the intrinsically faster pacemaker cell and it can be predicted from the diastolic depolarization times of both cells. Evidence is provided that, at low coupling conductances, mutual pacemaker synchronization results mainly from the phase-resetting effects of the action potential of one cell on the depolarization phase of the other. At high coupling conductances, the tonic, diastolic interactions become more important