Effects of dietary vitamin C supplementation on some oxidative status biomarkers in erythrocytes of common carp (Cyprinus carpio)

Regarding to the high content of polyunsaturated fatty acids in fish tissues, improving the fish antioxidant status seems to be necessary and may be associated with beneficial effects on fish health. The present study aimed to investigate the effects of dietary vitamin C supplementation (20 mg/kg body weight, 4 weeks) on some oxidative status biomarkers in RBC of common carp (Cyprinus carpio). The results showed that the activities of antioxidant enzymes including catalase (CAT), glutathione peroxidase (GPx) and superoxide dismutase (SOD) were not changed significantly following dietary vitamin C supplementation in comparison to the control group. Moreover, dietary vitamin C supplementation for 28 days significantly lowered malondialdehyde (MDA) concentration in erythrocyte haemolysate by approximately 26% compared to that of the control group. In conclusion, dietary vitamin C supplementation appears to be able to protect carp erythrocytes against oxidative stress by decreasing lipid peroxidation

The effects of dietary nucleotide content on the growth performance, digestibility and immune responses of juvenile narrow clawed crayfish, Astacus leptodactylus leptodactylus Eschscholtz, 1823

A 126-day experiment was carried out under controlled conditions to compare the effects of five levels (0.5, 1.0, 1.5, 2.0 and 2.5 g kg � 1 ) of dietar

The Effect of Vitamin C on Lead-induced Plasma BiochemicalAlterations in Fish, Cyprinus carpio

Background: This study was conducted to investigate whether vitamin C can protect against plasma biochemical changes induced by lead poisoning in Cyprinus carpio. Methods: Three groups of common carp (n=30/group) were used in this study. Group 1 served as control, Group 2 was exposed to lead acetate (5 mg/L) for 15 days, and Group 3 received vitamin C (500 mg/kg) during the same duration of lead exposure. Results: The blood lead concentrations in Groups 2 and 3 showed a significant rise as compared to that in the control group (p<0.05). Also, the plasma malondialdehyde (MDA) concentration increased considerably following in groups exposed to lead acetate, compared to that in controls. Vitamin C supplementation decreased the rise in plasma MDA insignificantly, compared that in Group 2. The plasma values of creatinine and alanine aminotransferase (ALT) increased in Group 2 compared to that in controls. Also, vitamin C treatment significantly decreased plasma ALT and creatinine concentrations, compared to those in Group 2. Values of other plasma parameters including aspartate aminotransferase, alkaline phosphatase, lactate dehydrogenase, gammaglutamyl transferase, albumin, glucose, total protein, cholesterol, urea, uric acid and triglyceride showed no significant alterations among the treatment groups. Conclusion: The results suggest that vitamin C have some beneficial effects against lead toxicity in common carp. However, elucidation of the precise mechanism of the protective effects of vitamin C against lead toxicity warrants further investigations