1,884 research outputs found

    Universality in Fluid Domain Coarsening: The case of vapor-liquid transition

    Full text link
    Domain growth during the kinetics of phase separation is studied following vapor-liquid transition in a single component Lennard-Jones fluid. Results are analyzed after appropriately mapping the continuum snapshots obtained from extensive molecular dynamics simulations to a simple cubic lattice. For near critical quench interconnected domain morphology is observed. A brief period of slow diffusive growth is followed by a linear viscous hydrodynamic growth that lasts for an extended period of time. This result is in contradiction with earlier inclusive reports of late time growth exponent 1/2 that questions the uniqueness of the non-equilibrium universality for liquid-liquid and vapor-liquid transitions.Comment: 6 pages, 5 figure

    Impact of transcranial direct current stimulation (tDCS) on neuronal functions

    Get PDF
    Transcranial direct current stimulation (tDCS), a non-invasive brain stimulation technique, modulates neuronal excitability by the application of a small electrical current. The low cost and ease of the technique has driven interest in potential clinical applications. However, outcomes are highly sensitive to stimulation parameters, leading to difficulty maximizing the technique's effectiveness. Although reversing the polarity of stimulation often causes opposite effects, this is not always the case. Effective clinical application will require an understanding of how tDCS works; how it modulates a neuron; how it affects the local network; and how it alters inter-network signaling. We have summarized what is known regarding the mechanisms of tDCS from sub-cellular processing to circuit level communication with a particular focus on what can be learned from the polarity specificity of the effects

    FPGA based Security Login System using GSM with OTP Generation

    Full text link
    Security of system is major concern in this age of high-tech infrastructure. In today\u27s materialistic world, security holds an in dispensable place. Security in every aspect is highly desirable may be at home or at office etc. as thefts and robberies are increasing day by day. To overcome this security threat, a security system has been proposed using GSM technology, by generating One Time Password and implementing in FPGA. As FPGAs offer all of the features needed to implement most complex designs. This security system activates, authenticates and validates the user and then unlocks the system. This project attempts to create security login systemwhere the user is granted access if he enters the correct predefined password and is denied access if he enter the wrong password. When password is entered GSM gets activated and send SMS to user\u27s mobile phone, after authentication random OTP is generated and should be verified such that the system gets accessed. In every 3 minutes this OTP verification code will change and is valid for 3 minutes. The outcome of each and all would be available in the LCD of the Spartan 3E board. VHDL codes are used to design this system using Xilinx ISE 9.2i

    Simulations of a weakly conducting droplet under the influence of an alternating electric field

    Full text link
    We investigate the electrohydrodynamics of an initially spherical droplet under the influence of an external alternating electric field by conducting axisymmetric numerical simulations using a charge-conservative volume-of-fluid based finite volume flow solver. The mean amplitude of shape oscillations of a droplet subjected to an alternating electric field for leaky dielectric fluids is the same as the steady-state deformation under an equivalent root mean squared direct electric field for all possible electrical conductivity ratio (Kr)(K_r) and permittivity ratio (S)(S) of the droplet to the surrounding fluid. In contrast, our simulations for weakly conducting media show that this equivalence between alternating and direct electric fields does not hold for KrSK_r \ne S. Moreover, for a range of parameters, the deformation obtained using the alternating and direct electric fields is qualitatively different, i.e. for low KrK_r and high SS, the droplet becomes prolate under alternating electric field but deforms to an oblate shape in the case of the equivalent direct electric field. A parametric study is conducted by varying the time period of the applied alternating electric field, the permittivity and the electrical conductivity ratios. It is observed that while increasing KrK_r has a negligible effect on the deformation dynamics of the droplet for Kr<SK_r<S, it enhances the deformation of the droplet when Kr>SK_r>S for both alternating and direct electric fields. We believe that our results may be of immense consequence in explaining the morphological evolution of droplets in a plethora of scenarios ranging from nature to biology.Comment: 10 pages, 8 figure

    A Neuroanatomically Grounded Optimal Control Model of the Compensatory Eye Movement System in Mice

    Get PDF
    We present a working model of the compensatory eye movement system in mice. We challenge the model with a data set of eye movements in mice (n =34) recorded in 4 different sinusoidal stimulus conditions with 36 different combinations of frequency (0.1–3.2 Hz) and amplitude (0.5–8°) in each condition. The conditions included vestibular stimulation in the dark (vestibular-ocular reflex, VOR), optokinetic stimulation (optokinetic reflex, OKR), and two combined visual/vestibular conditions (the visual-vestibular ocular reflex, vVOR, and visual suppression of the VOR, sVOR). The model successfully reproduced the eye movements in all conditions, except for minor failures to predict phase when gain was very low. Most importantly, it could explain the interaction of VOR and OKR when the two reflexes are activated simultaneously during vVOR stimulation. In addition to our own data, we also reproduced the behavior of the compensatory eye movement system found in the existing literature. These include its response to sum-of-sines stimuli, its response after lesions of the nucleus prepositus hypoglossi or the flocculus, characteristics of VOR adaptation, and characteristics of drift in the dark. Our model is based on ideas of state prediction and forward modeling that have been widely used in the study of motor control. However, it represents one of the first quantitative efforts to simulate the full range of behaviors of a specific system. The model has two separate processing loops, one for vestibular stimulation and one for visual stimulation. Importantly, state prediction in the visual processing loop depends on a forward model of residual ret

    Influenza A Virus Hemagglutinin Antibody Escape Promotes Neuraminidase Antigenic Variation and Drug Resistance

    Get PDF
    Drugs inhibiting the influenza A virus (IAV) neuraminidase (NA) are the cornerstone of anti-IAV chemotherapy and prophylaxis in man. Drug-resistant mutations in NA arise frequently in human isolates, limiting the therapeutic application of NA inhibitors. Here, we show that antibody-driven antigenic variation in one domain of the H1 hemagglutinin Sa site leads to compensatory mutations in NA, resulting in NA antigenic variation and acquisition of drug resistance. These findings indicate that influenza A virus resistance to NA inhibitors can potentially arise from antibody driven HA escape, confounding analysis of influenza NA evolution in nature

    High photon energy spectroscopy of NiO: experiment and theory

    Get PDF
    We have revisited the valence band electronic structure of NiO by means of hard x-ray photoemission spectroscopy (HAXPES) together with theoretical calculations using both the GW method and the local density approximation + dynamical mean-field theory (LDA+DMFT) approaches. The effective impurity problem in DMFT is solved through the exact diagonalization (ED) method. We show that the LDA+DMFT method alone cannot explain all the observed structures in the HAXPES spectra. GW corrections are required for the O bands and Ni-s and p derived states to properly position their binding energies. Our results establish that a combination of the GW and DMFT methods is necessary for correctly describing the electronic structure of NiO in a proper ab-initio framework. We also demonstrate that the inclusion of photoionization cross section is crucial to interpret the HAXPES spectra of NiO.We argue that our conclusions are general and that the here suggested approach is appropriate for any complex transition metal oxide.Comment: 16 pages, 5 figure
    corecore