315 research outputs found

    Numerical aspects of spatio-temporal current density reconstruction from EEG-/MEG-data

    Full text link

    From Labyrinth to Piano Key Weirs – A historical review

    Get PDF
    Free crest spillways are hydraulically efficient and safe in operation. Since their discharge capacity is directly proportional to the crest length several types have been developed with the purpose to increase the length of the latter. Among these types traditional labyrinth weir spillways have been studied and used for a long time. Their hydraulic performance and the effect of the involved geometrical parameters are well known. Nevertheless, their design still has to be based on experimentally derived and generalized performance curves. The recently introduced Piano Key weirs present clear advantages regarding hydraulic performance and construction costs compared to classical labyrinth weirs. Especially its small footprint makes the PK weir an efficient and cost effective solution for the increase of the flood releasing capacity at existing concrete gravity dams. Until today only preliminary design procedures are available which cannot yet be generalized. The still ongoing research on this complex hydraulic structure is a challenge for many scientists all over the world. Despite of this, several prototypes have been installed successfully over the last years on existing dams which enhance efficiently the flood release capacity

    Floating Patches of HCN at the Surface of Their Aqueous Solutions - Can They Make "HCN World" Plausible?

    Get PDF
    The liquid/vapor interface of the aqueous solutions of HCN of different concentrations has been investigated using molecular dynamics simulation and intrinsic surface analysis. Although HCN is fully miscible with water, strong interfacial adsorption of HCN is observed at the surface of its aqueous solutions, and, at the liquid surface, the HCN molecules tend to be located even at the outer edge of the surface layer. It turns out that in dilute systems the HCN concentration can be about an order of magnitude larger in the surface layer than in the bulk liquid phase. Furthermore, HCN molecules show a strong lateral self-association behavior at the liquid surface, forming thus floating HCN patches at the surface of their aqueous solutions. Moreover, HCN molecules are staying, on average, an order of magnitude longer at the liquid surface than water molecules, and this behavior is more pronounced at smaller HCN concentrations. Because of this enhanced dynamical stability, the floating HCN patches can provide excellent spots for polymerization of HCN, which can be the key step in the prebiotic synthesis of partially water-soluble adenine. All of these findings make the hypothesis of "HCN world" more plausible

    Long-Term Memory for Pavlovian Fear Conditioning Requires Dopamine in the Nucleus Accumbens and Basolateral Amygdala

    Get PDF
    The neurotransmitter dopamine (DA) is essential for learning in a Pavlovian fear conditioning paradigm known as fear-potentiated startle (FPS). Mice lacking the ability to synthesize DA fail to learn the association between the conditioned stimulus and the fear-inducing footshock. Previously, we demonstrated that restoration of DA synthesis to neurons of the ventral tegmental area (VTA) was sufficient to restore FPS. Here, we used a target-selective viral restoration approach to determine which mesocorticolimbic brain regions receiving DA signaling from the VTA require DA for FPS. We demonstrate that restoration of DA synthesis to both the basolateral amygdala (BLA) and nucleus accumbens (NAc) is required for long-term memory of FPS. These data provide crucial insight into the dopamine-dependent circuitry involved in the formation of fear-related memory

    Financial Integration in Emerging Europe: An Enviable Development Opportunity with Tail Risks

    Full text link
    This paper draws on the experience of emerging Europe and argues that foreign capital is an enviable development opportunity with tail risks. Financial integration and foreign savings supported growth in the EU12 and EU candidate countries. We argue that this was possible because of EU membership (actual or potential) and its role as an anchor for expectations. In contrast, the eastern partnership states did not benefit from the foreign savings-growth link. But financial integration also led to a buildup of vulnerabilities and now exposes emerging Europe to prolonged uncertainty and financial deleveraging due to eurozone developments. Nonetheless, we believe that external imbalances should not be eradicated-nor should emerging Europe pursue a policy of self-insurance. Instead, what we refer to as an acyclical fiscal policy stance could serve to counterbalance private sector behavior. Going forward, a more proactive macroprudential policy will also be needed to limit financial system vulnerabilities when external imbalances are large
    • …
    corecore