14 research outputs found

    Prototyping an Egyptian revival. Laser scanning, 3D prints and sculpture to support the Echoes of Egypt exhibition

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    This paper aims to highlight the importance of 3D printing to support Cultural Heritage and related activities. We will demonstrate the advantages that a conscious employment of techniques and methods, together with the right expertise, could offer to an exhibition. We will detail the steps we took to produce a 1:1 copy of a medieval sphinx for the exhibition Echoes of Egypt: Conjuring the Land of the Pharaohs which took place at the Yale Peabody Museum of Natural History (USA). This paper highlights the project’s workflow, from the digital 3D scan, data processing, 3D printing, to the artistic finishing to prepare the object for display

    Stat3 activation is required for cellular transformation by v-src

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    Stat3 activation has been associated with cytokine-induced proliferation, anti-apoptosis, and transformation. Constitutively activated Stat3 has been found in many human tumors as well as v-abl- and v-src-transformed cell lines. Because of these correlations, we examined directly the relationship of activated Stat3 to cellular transformation and found that wild-type Stat3 enhances the transforming potential of v-src while three dominant negative Stat3 mutants inhibit v-src transformation. Stat3 wild-type or mutant proteins did not affect v-ras transformation. We conclude that Stat3 has a necessary role in v-src transformation

    STAT3: A Potential Drug Target for Tumor and Inflammation

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    Targeting Immune Signaling Pathways in Clonal Hematopoiesis

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