30 research outputs found
Are pre-compiled citation indexes of peer-reviewed journals an adequate control for research quality? A case study of library and information science
Looks at the South African Department of Educationâs new recommendations for the evaluation of higher education research in South Africa, and examines two primary aspects: the use of pre-compiled journal lists from overseas, and the apparent reliance on peer review as a guarantee of quality. Pointing out that these are tried and tested standards of quality, the authors argue that there are nonetheless disciplinary differences between experimental sciences â such as physics or chemistry â and other disciplines that make these measures difficult to apply across the spectrum. They present an analysis of library and information science publications in the chosen lists and point to the weakness of the selection of titles in this discipline. In addition, there are extra difficulties for scientists from South Africa and the developing world in securing publication in premier international library and information science journals. The authors conclude by calling for the employment of other, additional evaluation measures in an integrated system
The Research Commons: a new creature in the library?
This is a post-print/preprint of an article published by Emerald in Performance Measurement and Metrics, VOL 11, available: http://dx.doi.org/10.1108/14678041011064043.Purpose â The purpose of this paper is to explore the use made of the Research Commons during its first year of operation in an attempt to establish whether it actually provides a genuinely new and different service from the point of view of the endâusers, and whether a facility such as this could indeed be presumed to support research and enhance research output at the university. Design/methodology/approach â Using Lippincott's assessment grid, an attempt was made to assess activities in the Research Commons according to the dimensions of extensiveness, efficiency, effectiveness, service quality and usefulness. Methodology was mixed, with quantitative and qualitative components that logged the extent and nature of the use of the various facilities in the Research Commons and sought to establish from stakeholder perceptions whether the services on offer are regarded as substantially different from those in the undergraduate Knowledge Commons and whether they are indeed seen to be supporting research activities. Findings â It was found that a combination of numerical and qualitative measurements has yielded sufficient evidence for the drawing of preliminary conclusions. The evidence gathered demonstrates that the Research Commons, designed primarily as a site for the creation of new knowledge in the form of original writing by researchers at postgraduate and academic level, is indeed an advance on the wellâestablished "library commons" concept, and that its creation represents an instance of "parallel invention" â the "new creature" that the title refers to. Originality/value â This paper provides a multifaceted perspective on the activities taking place in a new library facility and should provide librarians and researchers with evidenceâbased insight into how meaningful research support may be provided to young researchers from diverse linguistic and cultural backgrounds as part of an academic library service in a middle income country
El dossier copia/sur: problemas econĂłmicos, polĂticos, e ideolĂłgicos del copyright (derecho de autor) en el sur global
In 2005, a group of scholars and activists, mostly from the global South, created the Copy/South Research Group to analyse, criticise, and confront the oppressive nature of current global copyright regimes, such as those
defended by the World Intellectual Property Organisation, and similar ones around the globe. In May 2006, 22 of us, including 15 people from the global South, published THE COPY/SOUTH DOSSIER: Issues in the economics, politics, and ideology of copyright in the global South.
The aim of the Dossier was to open up a critical and radical debate on the real impact of copyright laws and how they affect the daily lives of people living in more than 150 developing countries of the global South. We also highlighted issues that are not unique to the Global South, but also affect both sides of the North-South divide. This publication of more than 50 articles was addressed to researchers, educators, librarians, musicians, activists, organizations concerned about access to knowledge, and all of those who want to learn more about the oppressive global role of copyright laws and, in particular, their largely negative role in the developing countries of the global South.
Given the democratic objectives of the Copy/South Research Group, the Dossier was not restricted by copyright. Therefore, it has been accessed openly and freely in both electronic and paper formats by thousands of readers from around the world in English. But English is not spoken by all citizens in the global South. With this in mind, the entire 200-page Dossier was translated into Spanish in late 2007 by an enthusiastic team of voluntary translators from Argentina, Bolivia, Cuba, Mexico, Spain, and Venezuela.
As for this Spanish version, made with the support of the Intellectual Property Automous Service (SAPI), from the Bolivarian Republic of Venezuela, we must acknowledge the prior SAPI's General Director Eduardo SamĂĄn for promoting the making of this translation. Besides the general revision of Gerardo CĂĄrdenas and his labor as main translator, some other volunteers translated or revised important sections of the Spanish edition: MarĂa JesĂșs
Morillo (Spain), Oscar PĂ©rez Peña and Gilda Gil (Cuba), Edgardo Civallero (Argentina) and Rafael Carreño (Venezuela), who coordinated the process of translation in 2007. Also it is worth to mention the additional colaboration of Ana LĂa LĂłpez (Bolivia), Richard Castro, Rafael Bellota and Carmen Chirinos (Venezuela), Zapopan Muela and Gonzalo Lara (Mexico), and Lilian Ălvarez (Cuba).
But what is still more extraordinary about this Spanish translation is that it was completely coordinated and edited by the Servicio Autonomo de la Propiedad Intelectual (SAPI) of the democratic government of the Venezuelan Bolivarian Republic. The Dossier provides âuseful material to introduce this topic to teachers and studentsâ and does a good job of âsummarizing a complex and conflicting situationâ for developing countries, Jumersi La Rosa, SAPIâs new director, said last week in announcing the release of the Spanish edition. She has written a special
new introduction for the Spanish-language edition.
The Copy South Research Group is very pleased that the radical message of resistance found in the Dossier can now be read by thousands of Spanish-language speakers who are questioning the current copyright regime and who hopefully will be ignited by the ideas in the Dossier to take up
the fight against oppressive regimes based on copyright.
You can get a copy of the Dossier in Spanish and English by downloading it, free of charge, at http://www.copysouth.org . We also still have a limited number of printed and bound copies of the English-language version of the Dossier. If you would to be mailed a copy of the English-language version, which contains eight posters, send us an e-mail ([email protected]) and include your full postal details. COPY/SOUTH RESEARCH GROUP, 28 April 2008
El dossier copia/sur: problemas econĂłmicos, polĂticos, e ideolĂłgicos del copyright (derecho de autor) en el sur global
In 2005, a group of scholars and activists, mostly from the global South, created the Copy/South Research Group to analyse, criticise, and confront the oppressive nature of current global copyright regimes, such as those
defended by the World Intellectual Property Organisation, and similar ones around the globe. In May 2006, 22 of us, including 15 people from the global South, published THE COPY/SOUTH DOSSIER: Issues in the economics, politics, and ideology of copyright in the global South.
The aim of the Dossier was to open up a critical and radical debate on the real impact of copyright laws and how they affect the daily lives of people living in more than 150 developing countries of the global South. We also highlighted issues that are not unique to the Global South, but also affect both sides of the North-South divide. This publication of more than 50 articles was addressed to researchers, educators, librarians, musicians, activists, organizations concerned about access to knowledge, and all of those who want to learn more about the oppressive global role of copyright laws and, in particular, their largely negative role in the developing countries of the global South.
Given the democratic objectives of the Copy/South Research Group, the Dossier was not restricted by copyright. Therefore, it has been accessed openly and freely in both electronic and paper formats by thousands of readers from around the world in English. But English is not spoken by all citizens in the global South. With this in mind, the entire 200-page Dossier was translated into Spanish in late 2007 by an enthusiastic team of voluntary translators from Argentina, Bolivia, Cuba, Mexico, Spain, and Venezuela.
As for this Spanish version, made with the support of the Intellectual Property Automous Service (SAPI), from the Bolivarian Republic of Venezuela, we must acknowledge the prior SAPI's General Director Eduardo SamĂĄn for promoting the making of this translation. Besides the general revision of Gerardo CĂĄrdenas and his labor as main translator, some other volunteers translated or revised important sections of the Spanish edition: MarĂa JesĂșs
Morillo (Spain), Oscar PĂ©rez Peña and Gilda Gil (Cuba), Edgardo Civallero (Argentina) and Rafael Carreño (Venezuela), who coordinated the process of translation in 2007. Also it is worth to mention the additional colaboration of Ana LĂa LĂłpez (Bolivia), Richard Castro, Rafael Bellota and Carmen Chirinos (Venezuela), Zapopan Muela and Gonzalo Lara (Mexico), and Lilian Ălvarez (Cuba).
But what is still more extraordinary about this Spanish translation is that it was completely coordinated and edited by the Servicio Autonomo de la Propiedad Intelectual (SAPI) of the democratic government of the Venezuelan Bolivarian Republic. The Dossier provides âuseful material to introduce this topic to teachers and studentsâ and does a good job of âsummarizing a complex and conflicting situationâ for developing countries, Jumersi La Rosa, SAPIâs new director, said last week in announcing the release of the Spanish edition. She has written a special
new introduction for the Spanish-language edition.
The Copy South Research Group is very pleased that the radical message of resistance found in the Dossier can now be read by thousands of Spanish-language speakers who are questioning the current copyright regime and who hopefully will be ignited by the ideas in the Dossier to take up
the fight against oppressive regimes based on copyright.
You can get a copy of the Dossier in Spanish and English by downloading it, free of charge, at http://www.copysouth.org . We also still have a limited number of printed and bound copies of the English-language version of the Dossier. If you would to be mailed a copy of the English-language version, which contains eight posters, send us an e-mail ([email protected]) and include your full postal details. COPY/SOUTH RESEARCH GROUP, 28 April 2008
Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial
Background
Previous evidence indicates that adjuvant, short-course androgen deprivation therapy (ADT) improves metastasis-free survival when given with primary radiotherapy for intermediate-risk and high-risk localised prostate cancer. However, the value of ADT with postoperative radiotherapy after radical prostatectomy is unclear.
Methods
RADICALS-HD was an international randomised controlled trial to test the efficacy of ADT used in combination with postoperative radiotherapy for prostate cancer. Key eligibility criteria were indication for radiotherapy after radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to radiotherapy alone (no ADT) or radiotherapy with 6 months of ADT (short-course ADT), using monthly subcutaneous gonadotropin-releasing hormone analogue injections, daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as distant metastasis arising from prostate cancer or death from any cause. Standard survival analysis methods were used, accounting for randomisation stratification factors. The trial had 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 80% to 86% (hazard ratio [HR] 0·67). Analyses followed the intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and ClinicalTrials.gov, NCT00541047.
Findings
Between Nov 22, 2007, and June 29, 2015, 1480 patients (median age 66 years [IQR 61â69]) were randomly assigned to receive no ADT (n=737) or short-course ADT (n=743) in addition to postoperative radiotherapy at 121 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 9·0 years (IQR 7·1â10·1), metastasis-free survival events were reported for 268 participants (142 in the no ADT group and 126 in the short-course ADT group; HR 0·886 [95% CI 0·688â1·140], p=0·35). 10-year metastasis-free survival was 79·2% (95% CI 75·4â82·5) in the no ADT group and 80·4% (76·6â83·6) in the short-course ADT group. Toxicity of grade 3 or higher was reported for 121 (17%) of 737 participants in the no ADT group and 100 (14%) of 743 in the short-course ADT group (p=0·15), with no treatment-related deaths.
Interpretation
Metastatic disease is uncommon following postoperative bed radiotherapy after radical prostatectomy. Adding 6 months of ADT to this radiotherapy did not improve metastasis-free survival compared with no ADT. These findings do not support the use of short-course ADT with postoperative radiotherapy in this patient population
Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial
Background
Previous evidence supports androgen deprivation therapy (ADT) with primary radiotherapy as initial treatment for intermediate-risk and high-risk localised prostate cancer. However, the use and optimal duration of ADT with postoperative radiotherapy after radical prostatectomy remains uncertain.
Methods
RADICALS-HD was a randomised controlled trial of ADT duration within the RADICALS protocol. Here, we report on the comparison of short-course versus long-course ADT. Key eligibility criteria were indication for radiotherapy after previous radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to add 6 months of ADT (short-course ADT) or 24 months of ADT (long-course ADT) to radiotherapy, using subcutaneous gonadotrophin-releasing hormone analogue (monthly in the short-course ADT group and 3-monthly in the long-course ADT group), daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as metastasis arising from prostate cancer or death from any cause. The comparison had more than 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 75% to 81% (hazard ratio [HR] 0·72). Standard time-to-event analyses were used. Analyses followed intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and
ClinicalTrials.gov
,
NCT00541047
.
Findings
Between Jan 30, 2008, and July 7, 2015, 1523 patients (median age 65 years, IQR 60â69) were randomly assigned to receive short-course ADT (n=761) or long-course ADT (n=762) in addition to postoperative radiotherapy at 138 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 8·9 years (7·0â10·0), 313 metastasis-free survival events were reported overall (174 in the short-course ADT group and 139 in the long-course ADT group; HR 0·773 [95% CI 0·612â0·975]; p=0·029). 10-year metastasis-free survival was 71·9% (95% CI 67·6â75·7) in the short-course ADT group and 78·1% (74·2â81·5) in the long-course ADT group. Toxicity of grade 3 or higher was reported for 105 (14%) of 753 participants in the short-course ADT group and 142 (19%) of 757 participants in the long-course ADT group (p=0·025), with no treatment-related deaths.
Interpretation
Compared with adding 6 months of ADT, adding 24 months of ADT improved metastasis-free survival in people receiving postoperative radiotherapy. For individuals who can accept the additional duration of adverse effects, long-course ADT should be offered with postoperative radiotherapy.
Funding
Cancer Research UK, UK Research and Innovation (formerly Medical Research Council), and Canadian Cancer Society
Recommended from our members
The Research Libraries Consortium: a Project funded by the Carnegie Corporation of New York
'A New Model for Research Support: Integrating Skills, Scholarship, and Technology in a South African Library Consortium' Poster presentation from the Living the Future 7 Conference, April 30-May 3, 2008, University of Arizona Libraries, Tucson, AZ.The project - A New Model for Research Support: Integrating Skills, Scholarship, and Technology in a South African Library Consortium - aims to model the transformation and enrichment of support to researchers offered by South African academic libraries. The guiding premise of this project is that the three institutions should take advantage of existing strengths as South Africaâs leading academic libraries to sustain, improve, and consolidate the troubled research enterprise in South Africa. Funded by the Carnegie Corporation this innovative program seeks to achieve its objectives through a multi-pronged project with three closely interrelated components: 1. Building a sophisticated Web-based shared portal which will provide access to a wide range of international and local electronic content for postgraduate students and academics; 2. Enhancing the skills of existing library staff in order to create a critical mass of support for research to be offered by librarians with real subject expertise (the South African Library Academy at the Mortenson Center and observation at a major US research library). 3. Creating a technologically sophisticated physical space - a 'one-stop shop' - for postgraduates and academic staff who need assistance with research.This item is part of the Living the Future collection. For more information about items in this collection, please email [email protected]